Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Alexander, Wilmer"'
Autor:
Jan Gunst, Liese Mebis, Pieter J. Wouters, Greet Hermans, Jasperina Dubois, Alexander Wilmer, Eric Hoste, Dominique Benoit, Greet Van den Berghe
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background It remains controversial whether critical illness-related hyperglycemia should be treated or not, since randomized controlled trials (RCTs) have shown context-dependent outcome effects. Whereas pioneer RCTs found improved outcome
Externí odkaz:
https://doaj.org/article/73eef13820f941ffbbe6373e077360a8
Autor:
Matthias M. Engelen, Quentin Van Thillo, Albrecht Betrains, Iwein Gyselinck, Caroline P. Martens, Valérie Spalart, Anna Ockerman, Caroline Devooght, Joost Wauters, Jan Gunst, Carine Wouters, Christophe Vandenbriele, Steffen Rex, Laurens Liesenborghs, Alexander Wilmer, Philippe Meersseman, Greet Van den Berghe, Dieter Dauwe, Ann Belmans, Michiel Thomeer, Tom Fivez, Dieter Mesotten, David Ruttens, Luc Heytens, Ilse Dapper, Sebastiaan Tuyls, Brecht De Tavernier, Peter Verhamme, Thomas Vanassche, DAWn Consortium Members
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 7, Pp n/a-n/a (2022)
Abstract Background Thromboinflammation plays a central role in severe COVID‐19. The kallikrein pathway activates both inflammatory pathways and contact‐mediated coagulation. We investigated if modulation of the thromboinflammatory response impro
Externí odkaz:
https://doaj.org/article/0b44d597e02c4aa1ae0a47b3c5ef8724
Autor:
Bert Malengier-Devlies, Jessica Filtjens, Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Greet Hermans, Philippe Meersseman, Alexander Wilmer, Mieke Gouwy, Abhishek D. Garg, Stephanie Humblet-Baron, Frederik De Smet, Kimberly Martinod, Els Wauters, Paul Proost, Carine Wouters, Georges Leclercq, Diether Lambrechts, Joost Wauters, Patrick Matthys
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we analysed the phenotype and activity of NK cells in the bloo
Externí odkaz:
https://doaj.org/article/13d4db38766a497bbdb3b0ba63a9215a
Autor:
Dominique D. Benoit, Esther N. van der Zee, Michael Darmon, An K. L. Reyners, Victoria Metaxa, Djamel Mokart, Alexander Wilmer, Pieter Depuydt, Andreas Hvarfner, Katerina Rusinova, Jan G.Zijlstra, François Vincent, Dimitrios Lathyris, Anne-Pascale Meert, Jacques Devriendt, Emma Uyttersprot, Erwin J. O. Kompanje, Ruth Piers, Elie Azoulay
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background Whether Intensive Care Unit (ICU) clinicians display unconscious bias towards cancer patients is unknown. The aim of this study was to compare the outcomes of critically ill patients with and without perceptions of excessive care
Externí odkaz:
https://doaj.org/article/da59897d16dc495ebbf35a7f7966af07
Autor:
Caroline P. Martens, Pierre Van Mol, Joost Wauters, Els Wauters, Tanja Gangnus, Bernard Noppen, Hanne Callewaert, Jean H.M. Feyen, Laurens Liesenborghs, Elisabeth Heylen, Sander Jansen, Leydi Carolina Velásquez Pereira, Sirima Kraisin, Ipek Guler, Matthias M. Engelen, Anna Ockerman, Anke Van Herck, Robin Vos, Christophe Vandenbriele, Philippe Meersseman, Greet Hermans, Alexander Wilmer, Kimberly Martinod, Bjoern B. Burckhardt, Marc Vanhove, Marc Jacquemin, Peter Verhamme, Johan Neyts, Thomas Vanassche
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104195- (2022)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-converting enzyme 2 (ACE2) receptor, a critical component of the kallikrein-kinin system. Its dysregulation may lead to increased vascular perm
Externí odkaz:
https://doaj.org/article/e22bccf7e13b4f4e9d17aa33606b5009
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/73230dc89fc840f1942c3e8317edeb19
Autor:
Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald, Alexander Wilmer, Jan Wernerman, Carina Benstoem, Michael P. Casaer, Joel Starkopf, Arthur van Zanten, Olav Rooyackers, Stephan M. Jakob, Cecilia I. Loudet, Danielle E. Bear, Gunnar Elke, Matthias Kott, Ingmar Lautenschläger, Jörn Schäper, Jan Gunst, Christian Stoppe, Leda Nobile, Valentin Fuhrmann, Mette M. Berger, Heleen M. Oudemans-van Straaten, Yaseen M. Arabi, Adam M. Deane, on behalf of the Working Group on Gastrointestinal Function within the Section of Metabolism, Endocrinology and Nutrition (MEN Section) of ESICM
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-17 (2020)
Abstract Background Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and therapeutic approaches. We aimed to develop a research agenda for GI dysfun
Externí odkaz:
https://doaj.org/article/d628f55091f4435a84157bd898e79494
Autor:
Lisa Van Dyck, Ilse Vanhorebeek, Alexander Wilmer, An Schrijvers, Inge Derese, Liese Mebis, Pieter J. Wouters, Greet Van den Berghe, Jan Gunst, Michaël P. Casaer
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background In two recent randomized controlled trials, withholding parenteral nutrition early in critical illness improved outcome as compared to early up-to-calculated-target nutrition, which may be explained by beneficial effects of fastin
Externí odkaz:
https://doaj.org/article/809d963eec3044768c225b8bb3f2f107
Autor:
Matthias M. Engelen, Christophe Vandenbriele, Valérie Spalart, Caroline P. Martens, Bert Vandenberk, Pieter Sinonquel, Natalie Lorent, Paul De Munter, Rik Willems, Joost Wauters, Alexander Wilmer, Dieter Dauwe, Jan Gunst, Ipek Guler, Stefan Janssens, Kimberly Martinod, Griet Pieters, Kathelijne Peerlinck, Peter Verhamme, Thomas Vanassche
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 3, Pp n/a-n/a (2022)
Abstract Background Venous thromboembolism (VTE) frequently occurs in hospitalized patients with coronavirus disease 2019 (COVID‐19). The optimal dose of anticoagulation for thromboprophylaxis in COVID‐19 is unknown. Aims To report VTE incidence
Externí odkaz:
https://doaj.org/article/2c1238428a3c4e769f7bde88fe726124
Autor:
Seppe Cambier, Mieke Metzemaekers, Ana Carolina de Carvalho, Amber Nooyens, Cato Jacobs, Lore Vanderbeke, Bert Malengier-Devlies, Mieke Gouwy, Elisabeth Heylen, Philippe Meersseman, Greet Hermans, Els Wauters, Alexander Wilmer, the CONTAGIOUS Consortium, Dominique Schols, Patrick Matthys, Ghislain Opdenakker, Rafael Elias Marques, Joost Wauters, Jennifer Vandooren, Paul Proost
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Neutrophils are recognized as important circulating effector cells in the pathophysiology of severe coronavirus disease 2019 (COVID-19). However, their role within the inflamed lungs is incompletely understood. Here, we collected bronchoalveolar lava
Externí odkaz:
https://doaj.org/article/827151a3853f4fa29df87b693838bc11