Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Alexander, Shirokov"'
Autor:
Michel Baudry, Yubin Wang, Xiaoning Bi, Yun Lyna Luo, Zhijun Wang, Zeechan Kamal, Alexander Shirokov, Ed Sullivan, Dennis Lagasca, Hany Khalil, Gary Lee, Kathy Fosnaugh, Philippe Bey, Shujaath Mehdi, Greg Coulter
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 2, Pp n/a-n/a (2024)
Abstract Our laboratory has shown that calpain‐2 activation in the brain following acute injury is directly related to neuronal damage and the long‐term functional consequences of the injury, while calpain‐1 activation is generally neuroprotect
Externí odkaz:
https://doaj.org/article/6f9db8b3fcb74ef09bea457d69a31b76
Autor:
Dongyu Li, Shaojun Liu, Tingting Yu, Zhang Liu, Silin Sun, Denis Bragin, Alexander Shirokov, Nikita Navolokin, Olga Bragina, Zhengwu Hu, Jürgen Kurths, Ivan Fedosov, Inna Blokhina, Alexander Dubrovski, Alexander Khorovodov, Andrey Terskov, Maria Tzoy, Oxana Semyachkina-Glushkovskaya, Dan Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Intraventricular hemorrhage is one of the most fatal forms of brain injury that is a common complication of premature infants. However, the therapy of this type of hemorrhage is limited, and new strategies are needed to reduce hematoma expan
Externí odkaz:
https://doaj.org/article/ff00bc5bdc4147e58a82b336d158ddf1
Autor:
Alexander Shirokov, Inna Blokhina, Ivan Fedosov, Egor Ilyukov, Andrey Terskov, Dmitry Myagkov, Dmitry Tuktarov, Maria Tzoy, Viktoria Adushkina, Daria Zlatogosrkaya, Arina Evsyukova, Valeria Telnova, Alexander Dubrovsky, Alexander Dmitrenko, Maria Manzhaeva, Valeria Krupnova, Matvey Tuzhilkin, Inna Elezarova, Nikita Navolokin, Elena Saranceva, Tatyana Iskra, Ekaterina Lykova, Oxana Semyachkina-Glushkovskaya
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 262 (2024)
There is an association between sleep quality and glioma-specific outcomes, including survival. The critical role of sleep in survival among subjects with glioma may be due to sleep-induced activation of brain drainage (BD), that is dramatically supp
Externí odkaz:
https://doaj.org/article/747d704405f148d4a9423f218e46b300
Autor:
Oxana Semyachkina-Glushkovskaya, Konstantin Sergeev, Nadezhda Semenova, Andrey Slepnev, Anatoly Karavaev, Alexey Hramkov, Mikhail Prokhorov, Ekaterina Borovkova, Inna Blokhina, Ivan Fedosov, Alexander Shirokov, Alexander Dubrovsky, Andrey Terskov, Maria Manzhaeva, Valeria Krupnova, Alexander Dmitrenko, Daria Zlatogorskaya, Viktoria Adushkina, Arina Evsukova, Matvey Tuzhilkin, Inna Elizarova, Egor Ilyukov, Dmitry Myagkov, Dmitry Tuktarov, Jürgen Kurths
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1605 (2023)
Anesthesia enables the painless performance of complex surgical procedures. However, the effects of anesthesia on the brain may not be limited only by its duration. Also, anesthetic agents may cause long-lasting changes in the brain. There is growing
Externí odkaz:
https://doaj.org/article/2b94dcccf58445beaf5446df7294ac82
Autor:
Oxana Semyachkina-Glushkovskaya, Sergey Sokolovski, Ivan Fedosov, Alexander Shirokov, Nikita Navolokin, Alla Bucharskaya, Inna Blokhina, Andrey Terskov, Alexander Dubrovski, Valeria Telnova, Anna Tzven, Maria Tzoy, Arina Evsukova, Daria Zhlatogosrkaya, Viktoria Adushkina, Alexander Dmitrenko, Maria Manzhaeva, Valeria Krupnova, Alessio Noghero, Denis Bragin, Olga Bragina, Ekaterina Borisova, Jürgen Kurths, Edik Rafailov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13696 (2023)
Over sixty years, laser technologies have undergone a technological revolution and become one of the main tools in biomedicine, particularly in neuroscience, neurodegenerative diseases and brain tumors. Glioblastoma is the most lethal form of brain c
Externí odkaz:
https://doaj.org/article/3fdec0125dc142889804d264cf8eb998
Autor:
Oxana Semyachkina-Glushkovskaya, Sergey Diduk, Eroshova Anna, Dosadina Elina, Kruglov Artem, Alexander Khorovodov, Alexander Shirokov, Ivan Fedosov, Alexander Dubrovsky, Inna Blokhina, Andrey Terskov, Nikita Navolokin, Arina Evsukova, Daria Elovenko, Viktoria Adushkina, Jürgen Kurths
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe development of new methods for modulation of drug distribution across to the brain is a crucial step in the effective therapies for glioblastoma (GBM). In our previous work, we discovered the phenomenon of music-induced opening of the b
Externí odkaz:
https://doaj.org/article/563ced6a93664ca7a24bef5fc8d04bff
Autor:
Nikita Navolokin, Maria Lomova, Alla Bucharskaya, Olga Godage, Natalya Polukonova, Alexander Shirokov, Vyacheslav Grinev, Galina Maslyakova
Publikováno v:
Materials, Vol 16, Iss 4, p 1470 (2023)
Flavonoid-containing Gratiola officinalis extract has been studied in relation to breast carcinoma and human cervical cancer cells in encapsulated and native form. Encapsulation was realized in polymer shells, which were formed by the layer-by-layer
Externí odkaz:
https://doaj.org/article/293ac23b9df14eccae515a2d1cd9a660
Autor:
Oxana Semyachkina-Glushkovskaya, Denis Bragin, Olga Bragina, Sergey Socolovski, Alexander Shirokov, Ivan Fedosov, Vasily Ageev, Inna Blokhina, Alexander Dubrovsky, Valeria Telnova, Andrey Terskov, Alexander Khorovodov, Daria Elovenko, Arina Evsukova, Maria Zhoy, Ilana Agranovich, Elena Vodovozova, Anna Alekseeva, Jürgen Kurths, Edik Rafailov
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 567 (2023)
The progress in brain diseases treatment is limited by the blood-brain barrier (BBB), which prevents delivery of the vast majority of drugs from the blood into the brain. In this study, we discover unknown phenomenon of opening of the BBBB (BBBO) by
Externí odkaz:
https://doaj.org/article/10d72f388cf4481caafa0aea59328abf
Autor:
Oxana Semyachkina-Glushkovskaya, Alexander Shirokov, Inna Blokhina, Valeria Telnova, Elena Vodovozova, Anna Alekseeva, Ivan Boldyrev, Ivan Fedosov, Alexander Dubrovsky, Alexandr Khorovodov, Andrey Terskov, Arina Evsukova, Daria Elovenko, Viktoria Adushkina, Maria Tzoy, Ilana Agranovich, Jürgen Kurths, Edik Rafailov
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 36 (2022)
The blood–brain barrier (BBB) limits the delivery of majority of cancer drugs and thereby complicates brain tumor treatment. The nasal-brain-lymphatic system is discussed as a pathway for brain drug delivery overcoming the BBB. However, in most cas
Externí odkaz:
https://doaj.org/article/478a46ba376c4e4dab39e1092bc7956d
Autor:
Oxana Semyachkina-Glushkovskaya, Alexander Khorovodov, Ivan Fedosov, Alexey Pavlov, Alexander Shirokov, Ali Esmat Sharif, Alexander Dubrovsky, Inna Blokhina, Andrey Terskov, Nikita Navolokin, Arina Evsukova, Georgy Karandin, Dariya Elovenko, Maria Tzoy, Vasily Ageev, Ilana Agranovich, Valeria Telnova, Anna Tsven, Elena Saranceva, Tatyana Iskra, Jürgen Kurths
Publikováno v:
Applied Sciences, Vol 11, Iss 21, p 10287 (2021)
The lymphatic system of the brain meninges and head plays a crucial role in the clearance of amyloid-β protein (Aβ), a peptide thought to be pathogenic in Alzheimer’s disease (AD), from the brain. The development of methods to modulate lymphatic
Externí odkaz:
https://doaj.org/article/e1ead22a95774fd7809d7e68d9f5eeea