Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Alexander, Schug"'
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Histidine kinases (HK) are one of the main prokaryotic signaling systems. Two structurally conserved catalytic domains inside the HK enable autokinase, phosphotransfer, and phosphatase activities. Here, we focus on a detailed mechanistic und
Externí odkaz:
https://doaj.org/article/0f8ce7285bc84937b7580e205689a34d
Autor:
Oskar Taubert, Fabrice von der Lehr, Alina Bazarova, Christian Faber, Philipp Knechtges, Marie Weiel, Charlotte Debus, Daniel Coquelin, Achim Basermann, Achim Streit, Stefan Kesselheim, Markus Götz, Alexander Schug
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract On the path to full understanding of the structure-function relationship or even design of RNA, structure prediction would offer an intriguing complement to experimental efforts. Any deep learning on RNA structure, however, is hampered by th
Externí odkaz:
https://doaj.org/article/d536d84aae0f4245a6e3998c83d5238a
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 3, p e1010471 (2023)
Progress continues in the field of cancer biology, yet much remains to be unveiled regarding the mechanisms of cancer invasion. In particular, complex biophysical mechanisms enable a tumor to remodel the surrounding extracellular matrix (ECM), allowi
Externí odkaz:
https://doaj.org/article/e6d3df10d1164458bf20e6379cd12935
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Discoveries in cellular dynamics and tissue development constantly reshape our understanding of fundamental biological processes such as embryogenesis, wound-healing, and tumorigenesis. High-quality microscopy data and ever-improv
Externí odkaz:
https://doaj.org/article/0e4cc4c4dac544ed8bc94c05a974c334
Autor:
Jakob Rosenbauer, Chengting Zhang, Benjamin Mattes, Ines Reinartz, Kyle Wedgwood, Simone Schindler, Claude Sinner, Steffen Scholpp, Alexander Schug
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 6, p e1007417 (2020)
During embryogenesis, morphogens form a concentration gradient in responsive tissue, which is then translated into a spatial cellular pattern. The mechanisms by which morphogens spread through a tissue to establish such a morphogenetic field remain e
Externí odkaz:
https://doaj.org/article/e76179fd45ed46c7b909d8a385675fd6
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242072 (2020)
Proteins are complex biomolecules which perform critical tasks in living organisms. Knowledge of a protein's structure is essential for understanding its physiological function in detail. Despite the incredible progress in experimental techniques, pr
Externí odkaz:
https://doaj.org/article/afc4620d22a7437fa5d6f119309f68ac
Autor:
Ines Reinartz, Mona Sarter, Julia Otten, Henning Höfig, Martina Pohl, Alexander Schug, Andreas M. Stadler, Jörg Fitter
Publikováno v:
Sensors, Vol 21, Iss 12, p 4144 (2021)
Inspired by the modular architecture of natural signaling proteins, ligand binding proteins are equipped with two fluorescent proteins (FPs) in order to obtain Förster resonance energy transfer (FRET)-based biosensors. Here, we investigated a glucos
Externí odkaz:
https://doaj.org/article/3d73b935658b4092aef43fd9d3c28351
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006900 (2019)
The fundamental aim of structural analyses in biophysics is to reveal a mutual relation between a molecule's dynamic structure and its physiological function. Small-angle X-ray scattering (SAXS) is an experimental technique for structural characteriz
Externí odkaz:
https://doaj.org/article/3446b919f31949fd83e5622c78299ba4
Autor:
Alix Tröster, Michael DiPrima, Nathalie Jores, Denis Kudlinzki, Sridhar Sreeramulu, Santosh L. Gande, Verena Linhard, Damian Ludig, Alexander Schug, Krishna Saxena, Maria Reinecke, Stephanie Heinzlmeir, Matthias S. Leisegang, Jan Wollenhaupt, Frank Lennartz, Manfred S. Weiss, Bernhard Kuster, Giovanna Tosato, Harald Schwalbe
Publikováno v:
Chemistry – A European Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75f950211da3e2f3b3639be4b10d2350
https://doi.org/10.1002/chem.202300918
https://doi.org/10.1002/chem.202300918
Autor:
Alix Tröster, Michael DiPrima, Nathalie Jores, Denis Kudlinzki, Sridhar Sreeramulu, Santosh L. Gande, Verena Linhard, Damian Ludig, Alexander Schug, Krishna Saxena, Maria Reinecke, Stephanie Heinzlmeir, Matthias S. Leisegang, Jan Wollenhaupt, Frank Lennartz, Manfred S. Weiss, Bernhard Kuster, Giovanna Tosato, Harald Schwalbe
Publikováno v:
Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac07490436f87d653c2cdcf8a5c7701
https://doi.org/10.1002/chem.202203967
https://doi.org/10.1002/chem.202203967