Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alexander, Patrician"'
Autor:
Prajan Subedi, Christopher Gasho, Michael Stembridge, Alexandra M. Williams, Alexander Patrician, Philip N. Ainslie, James D. Anholm
Publikováno v:
Experimental Physiology, Vol 108, Iss 1, Pp 111-122 (2023)
Abstract Prolonged alveolar hypoxia leads to pulmonary vascular remodelling. We examined the time course at altitude, over which hypoxic pulmonary vasoconstriction goes from being acutely reversible to potentially irreversible. Study subjects were lo
Externí odkaz:
https://doaj.org/article/14c45d9702594740a9d007e981f1c48d
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Breath-hold diving (freediving) is an underwater sport that is associated with elevated hydrostatic pressure, which has a compressive effect on the lungs that can lead to the development of pulmonary edema. Pulmonary edema reduces oxygen uptake and t
Externí odkaz:
https://doaj.org/article/52ab40ece67c49748447310ae40f35e3
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Breath-hold diving involves highly integrative physiology and extreme responses to both exercise and asphyxia during progressive elevations in hydrostatic pressure. With astonishing depth records exceeding 100 m, and up to 214 m on a single breath, t
Externí odkaz:
https://doaj.org/article/c1030261d1fd40d797490f93a4dadbeb
Autor:
Jay MJR Carr, Philip N Ainslie, David B MacLeod, Joshua C Tremblay, Daniela Nowak-Flück, Connor A Howe, Mike Stembridge, Alexander Patrician, Geoff B Coombs, Benjamin S Stacey, Damian M Bailey, Daniel J Green, Ryan L Hoiland
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 43:99-114
This study investigated the influence of acute reductions in arterial O2 content (CaO2) via isovolumic haemodilution on global cerebral blood flow (gCBF) and cerebrovascular CO2 reactivity (CVR) in 11 healthy males (age; 28 ± 7 years: body mass inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e240a0f8e294cee21d2691e7c6f9b6b
https://doi.org/10.1177/0271678x221119442
https://doi.org/10.1177/0271678x221119442
Autor:
Tyler Kelly, Alexander Patrician, Mohini Bryant-Ekstrand, Courtney Brown, Christopher Gasho, Hannah G. Caldwell, Rachel N. Lord, Tony Dawkins, Aimee Drane, Michael Stembridge, Tanja Dragun, Otto Barak, Boris Spajić, Ivan Drviš, Joseph W. Duke, Glen E. Foster, Philip N. Ainslie, Željko Dujić, Andrew T. Lovering
Publikováno v:
Journal of Science and Medicine in Sport. 25:553-556
Objectives: During apnea diving, a patent foramen ovale may function as a pressure relief valve under conditions of high pulmonary pressure, preserving left-ventricular output. Patent foramen ovale prevalence in apneic divers has not been previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d6ab6005cab04fc7f19ec157ddeb7d
https://doi.org/10.1016/j.jsams.2022.03.014
https://doi.org/10.1016/j.jsams.2022.03.014
Autor:
Rita Sjöström, Lars Söderström, Carolina Klockmo, Alexander Patrician, Thomas Sandström, Glenn Björklund, Helen Hanstock, Nikolai Stenfors
Publikováno v:
International Journal of Circumpolar Health, Vol 78, Iss 1 (2019)
Background: Exposure to cold air is associated with increased morbidity and mortality in the general population. It is difficult to study the effects of whole-body exposure to cold air under controlled conditions in real life. Objectives: The aim of
Externí odkaz:
https://doaj.org/article/d3d341c407324437b3fd91ba949df084
Autor:
Gustavo Vizcardo-Galindo, Ryan L. Hoiland, Christopher Gasho, Francisco C. Villafuerte, Kaitlyn Tymko, Courtney Tymko, James D. Anholm, John D. Akins, Philip N. Ainslie, Michael M. Tymko, Travis D. Gibbons, Rachel Stone, Geoff B. Coombs, Mike Stembridge, Connor A. Howe, Damian M. Bailey, Joshua C. Tremblay, Tony G. Dawkins, Alexander Patrician, Benjamin S. Stacey, Rómulo Figueroa-Mujíca
Publikováno v:
Chest. 161:1022-1035
BACKGROUND: Increasing iron bioavailability attenuates hypoxic pulmonary vasoconstriction in both lowlanders and Sherpas at high altitude. In contrast, the pulmonary vasculature of Andeans with chronic mountain sickness (CMS) is resistant to iron adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b782c7ad08d714e67219d696a015ac2c
https://doi.org/10.1016/j.chest.2021.08.075
https://doi.org/10.1016/j.chest.2021.08.075
Autor:
Christopher K Willie, Michael Stembridge, Ryan L Hoiland, Michael M Tymko, Joshua C Tremblay, Alexander Patrician, Craig Steinback, Jonathan Moore, James Anholm, Prajan Subedi, Shailesh Niroula, Chris J McNeil, Ali McManus, David B MacLeod, Philip N Ainslie
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204660 (2018)
The University of British Columbia Nepal Expedition took place over several months in the fall of 2016 and was comprised of an international team of 37 researchers. This paper describes the objectives, study characteristics, organization and manageme
Externí odkaz:
https://doaj.org/article/4cca0ba07d064427bc8c651c3a6e9de1
Autor:
Jay Mjr, Carr, Philip N, Ainslie, David B, MacLeod, Joshua C, Tremblay, Daniela, Nowak-Flück, Connor A, Howe, Mike, Stembridge, Alexander, Patrician, Geoff B, Coombs, Benjamin S, Stacey, Damian M, Bailey, Daniel J, Green, Ryan L, Hoiland
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 43(1)
This study investigated the influence of acute reductions in arterial O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e80277b5f7462c3088f6f14cb604df6
https://pubmed.ncbi.nlm.nih.gov/36131560
https://pubmed.ncbi.nlm.nih.gov/36131560
Autor:
Thompson G. Robinson, Connor A. Howe, Philip N. Ainslie, Courtney V. Brown, Jay M. J. R. Carr, Alexander Patrician, Jatinder S. Minhas, Ronney B. Panerai, Hannah G. Caldwell, Carter J. Chalifoux, Joshua C. Tremblay, Ryan L. Hoiland
Publikováno v:
The Journal of Physiology. 599:3663-3676
KEY POINTS We investigated the influence of arterial PCO2 ( PaCO2 ) with and without acute experimental metabolic alkalosis on neurovascular coupling (NVC). We assessed stepwise iso-oxic alterations in PaCO2 prior to and following intravenous NaHCO3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f844a71e8783cb033ea71d4def2306ac
https://doi.org/10.1113/jp281615
https://doi.org/10.1113/jp281615