Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alexander, Gräwe"'
Autor:
Alexander Gräwe, Maarten Merkx
Publikováno v:
ACS Sensors, 7(12), 3800-3808. American Chemical Society
Bioluminescent sensor proteins have recently gained popularity in both basic research and point-of-care diagnostics. Sensor proteins based on intramolecular complementation of split NanoLuc are particularly attractive because their intrinsic modular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7300edf27324578634dc234586a6d1b2
https://doi.org/10.1021/acssensors.2c01726
https://doi.org/10.1021/acssensors.2c01726
Publikováno v:
Bioconjugate Chemistry, 33(7), 1415-1421. American Chemical Society
Linker engineering is rapidly gaining prominence as protein engineers and synthetic biologists construct increasingly sophisticated protein assemblies capable of executing complex molecular functions in the context of biosensing, biocatalysis, or bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c290b3ffb7c5c5b7f6de498d9042fb
http://www.scopus.com/inward/record.url?scp=85134720450&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85134720450&partnerID=8YFLogxK
Autor:
Alexander Gräwe, Anna Dreyer, Tobias Vornholt, Ursela Barteczko, Luzia Buchholz, Gila Drews, Uyen Linh Ho, Marta Eva Jackowski, Melissa Kracht, Janina Lüders, Tore Bleckwehl, Lukas Rositzka, Matthias Ruwe, Manuel Wittchen, Petra Lutter, Kristian Müller, Jörn Kalinowski
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0210940 (2019)
Biosensors have emerged as a valuable tool with high specificity and sensitivity for fast and reliable detection of hazardous substances in drinking water. Numerous substances have been addressed using synthetic biology approaches. However, many prop
Externí odkaz:
https://doaj.org/article/ded62c19d1814ee4853fd59f84eba526
Autor:
Viktor Stein, Alexander Gräwe
Publikováno v:
Trends in Biotechnology. 39:731-744
Linkers play critical roles in the construction of synthetic protein switches and sensors as they functionally couple a receptor with an actuator. With an increasing number of molecular toolboxes and experimental strategies becoming available that ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea35c517deabc0e18956d47ac5ce61ef
https://doi.org/10.1016/j.tibtech.2020.11.007
https://doi.org/10.1016/j.tibtech.2020.11.007
Publikováno v:
Methods in enzymology. 647
Linker engineering constitutes a critical, yet frequently underestimated aspect in the construction of synthetic protein switches and sensors. Notably, systematic strategies to engineer linkers by predictive means remain largely elusive to date. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5631f8f9bcb4a6b217f57208e85665f
https://pubmed.ncbi.nlm.nih.gov/33482991
https://pubmed.ncbi.nlm.nih.gov/33482991
Autor:
Wolfgang Ensinger, Lena K. Müller, Mubarak Ali, Ivana Duznovic, Alesia A. Tietze, Viktor Stein, Alexander Gräwe, Wadim Weber
Publikováno v:
Small 17(33), 2101066 (2021). doi:10.1002/smll.202101066
Small 17(33), 2101066 (2021). doi:10.1002/smll.202101066
Published by Wiley-VCH, Weinheim
Published by Wiley-VCH, Weinheim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0dc9d8b95e95eb07f12a5e3a956351
Publikováno v:
Linkers in Biomacromolecules ISBN: 9780128208182
Linker engineering constitutes a critical, yet frequently underestimated aspect in the construction of synthetic protein switches and sensors. Notably, systematic strategies to engineer linkers by predictive means remain largely elusive to date. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56cec0c81cb5617f168a73b56d6c6cdb
https://doi.org/10.1016/bs.mie.2020.09.009
https://doi.org/10.1016/bs.mie.2020.09.009
Publikováno v:
Current opinion in biotechnology. 63
Proteases have emerged as a promising class of enzymes to build post-translationally regulated signalling functions in diverse organisms and cell types ranging from simple prokaryotes to higher eukaryotes and in reconstituted systems in vitro. An exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b699102173396145b20dd8ed45b448
https://pubmed.ncbi.nlm.nih.gov/31698156
https://pubmed.ncbi.nlm.nih.gov/31698156
Publikováno v:
Neuroradiol J
We present the case of a 49-year-old woman with sudden onset of severe headaches and a ruptured aneurysm located inside the fenestration of the infraclinoid part of the internal carotid artery in the segments C4 and C5 distal to the origin of the oph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed617be78ac1813467005f35b2fa3e25
https://europepmc.org/articles/PMC6728702/
https://europepmc.org/articles/PMC6728702/
Publikováno v:
Journal of Neurosciences in Rural Practice, Vol 7, Iss 01, Pp 48-54 (2016)
Journal of Neurosciences in Rural Practice
67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCP 088 /20160608/
Journal of Neurosciences in Rural Practice
67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCP 088 /20160608/
Objective: Sophisticated shunt valves provide the possibility of pressure adjustment and antisiphon control but have a higher probability of valve dysfunction especially in a posthemorrhagic setting. The aim of the present study is to analyze the cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5445e483ee7062e08e29f9071090873c
http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.172159
http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.172159