Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Alexander, Götz"'
Autor:
Darius Hoffmeister, Selina Finger, Lena Fiedler, Tien‐Ching Ma, Andreas Körner, Matej Zlatar, Birk Fritsch, Kerstin Witte Bodnar, Simon Carl, Alexander Götz, Benjamin Apeleo Zubiri, Johannes Will, Erdmann Spiecker, Serhiy Cherevko, Anna T. S. Freiberg, Karl J. J. Mayrhofer, Simon Thiele, Andreas Hutzler, Chuyen van Pham
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract The widespread application of green hydrogen production technologies requires cost reduction of crucial elements. To achieve this, a viable pathway to reduce the iridium loading in proton exchange membrane water electrolysis (PEMWE) is explo
Externí odkaz:
https://doaj.org/article/927b0e3b2c7943cfb24ec6f86d7d4ac1
Autor:
Charlotte Spitz, Christine Schlosser, Nadja Guschtschin-Schmidt, Walter Stelzer, Simon Menig, Alexander Götz, Martina Haug-Kröper, Christina Scharnagl, Dieter Langosch, Claudia Muhle-Goll, Regina Fluhrer
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101775- (2020)
Summary: Ectodomain (EC) shedding defines the proteolytic removal of a membrane protein EC and acts as an important molecular switch in signaling and other cellular processes. Using tumor necrosis factor (TNF)α as a model substrate, we identify a no
Externí odkaz:
https://doaj.org/article/c3b63148f6c64088b959a5bd718b3a1c
Autor:
Martin Schumann, Johannes Munke, Stephan Hachinger, Patrick Hannawald, Inga Beck, Alexander Götz, Oleg Goussev, Jana Handschuh, Helmut Heller, Roland Mair, Till Rehm, Bianca Wittmann, Sabine Wüst, Michael Bittner, Jan Schmidt, Dieter Kranzlmüller
In this poster contribution, we present a scheduling system for automated remote operation of instruments at high-altitude research facilities and similar remote sites. Via web-based interfaces, the system allows instrument owners as well as authoriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4473fe845ac33ae43cd1212463e795
https://doi.org/10.5194/egusphere-egu23-237
https://doi.org/10.5194/egusphere-egu23-237
Autor:
Alexander Götz, Christina Scharnagl
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200077 (2018)
The mechanism by which familial Alzheimer's disease (FAD) mutations within the transmembrane domain (TMD) of the Amyloid Precursor Protein (APP) affect ε-endoproteolysis is only poorly understood. Thereby, mutations in the cleavage domain reduce ε-
Externí odkaz:
https://doaj.org/article/2406f160359f4f96ba627c9b8192655d
Autor:
Umair Sultan, Alexander Götz, Carola Schlumberger, Dominik Drobek, Gudrun Bleyer, Teresa Walter, Erik Löwer, Urs Alexander Peuker, Matthias Thommes, Erdmann Spiecker, Benjamin Apeleo Zubiri, Alexandra Inayat, Nicolas Vogel
Publikováno v:
Small. :2300241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec8d9e62aae38809326b99675fa8f15
https://doi.org/10.1002/smll.202300241
https://doi.org/10.1002/smll.202300241
Autor:
Dieter Langosch, Hannes Heinel, Christina Scharnagl, Claudia Muhle-Goll, Harald Steiner, Philipp Högel, Simon Menig, Daniel Huster, Alexander Götz, Nadine Mylonas, Frits Kamp, Burkhard Luy, Alexander Vogel, Mara Silber, Hannes Feyrer
Publikováno v:
Biophys J
Biophysical journal 116(11), 2103-2120 (2019). doi:10.1016/j.bpj.2019.04.030
Biophysical journal 116(11), 2103-2120 (2019). doi:10.1016/j.bpj.2019.04.030
Intramembrane cleavage of the β-amyloid precursor protein C99 substrate by γ-secretase is implicated in Alzheimer’s disease pathogenesis. Biophysical data have suggested that the N-terminal part of the C99 transmembrane domain (TMD) is separated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43179bc7d9a088e925fbc9d25ec19287
https://doi.org/10.1016/j.bpj.2019.04.030
https://doi.org/10.1016/j.bpj.2019.04.030
Autor:
Christina Scharnagl, Alexander Götz, Claudia Muhle-Goll, Dieter Langosch, Iro Chaitoglou, Philipp Högel, Mara Silber, Burkhard Luy
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Cleavage of the amyloid precursor protein’s (APP) transmembrane domain (TMD) by γ-secretase is a crucial step in the aetiology of Alzheimer’s Disease (AD). Mutations in the APP TMD alter cleavage and lead to familial forms of AD (FAD). The major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fb89a83f0fead6ae98887450db4cfe
http://link.springer.com/article/10.1038/s41598-019-41766-1
http://link.springer.com/article/10.1038/s41598-019-41766-1
Autor:
Sabine M Hölter, Mary Stromberg, Marina Kovalenko, Lillian Garrett, Lisa Glasl, Edith Lopez, Jolene Guide, Alexander Götz, Wolfgang Hans, Lore Becker, Birgit Rathkolb, Jan Rozman, Anja Schrewed, Martin Klingenspor, Thomas Klopstock, Holger Schulz, Eckhard Wolf, Wolfgang Wursta, Tammy Gillis, Hiroko Wakimoto, Jonathan Seidman, Marcy E MacDonald, Susan Cotman, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Jong-Min Lee, Vanessa C Wheeler
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80923 (2013)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in the HTT gene encoding huntingtin. The disease has an insidious course, typically progressing over 10-15 years until
Externí odkaz:
https://doaj.org/article/57b263b8d55c4fe881fd6b6ee0978b4a
Autor:
Jens Weismüller, Stephan Hachinger, Alexander Götz, Tobias Weber, Hai Nguyen, Johannes Munke, Mohamad Hayek
LTDS ("Let the Data Sing") is a lightweight, microservice-based Research Data Management (RDM) architecture which augments previously isolated data stores ("data silos") with FAIR research data repositories. The core components of LTDS include a meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab32c6bb0eb393a54e7cde4997ba85bb
https://doi.org/10.5194/egusphere-egu2020-7937
https://doi.org/10.5194/egusphere-egu2020-7937
Autor:
Johannes Munke, Alexander Götz, Helmut Heller, Stephan Hachinger, Dominik Laux, Oleg Goussev, Jana Handschuh, Sabine Wüst, Michael Bittner, Roland Mair, Bianca Wittmann, Till Rehm, Inga Beck, Markus Neumann
The AlpEnDAC (Alpine Environmental Data Analysis Center) platform (www.alpendac.eu) aims to collect scientific data measured on different high-altitude research stations in the alpine region and beyond. It provides research data management, analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbb4347219b369e0c2d29b67c7363b0
https://doi.org/10.5194/egusphere-egu2020-10660
https://doi.org/10.5194/egusphere-egu2020-10660