Zobrazeno 1 - 10
of 569
pro vyhledávání: '"Alexander, Enk"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Monoclonal antibodies, such as PD-1 inhibitors, are increasingly used in various cancers. Acute low back pain as infusion-related reaction (IRR) to monoclonal antibodies is poorly described. We report a bicentric series of 10 cases of acute low back
Externí odkaz:
https://doaj.org/article/bc9be32746094726bca763ff1eccc7bb
Autor:
Kaan Yilmaz, Stefanie Haeberle, Yong Ook Kim, Marvin J. Fritzler, Shih-Yen Weng, Benjamin Goeppert, Verena K. Raker, Kerstin Steinbrink, Detlef Schuppan, Alexander Enk, Eva N. Hadaschik
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionScurfy mice have a complete deficiency of functional regulatory T cells (Treg) due to a frameshift mutation in the Foxp3 gene. The impaired immune homeostasis results in a lethal lymphoproliferative disorder affecting multiple organs, inc
Externí odkaz:
https://doaj.org/article/a696944eb6ae4402b9488c883c8f0378
Publikováno v:
Case Reports in Dermatology, Vol 13, Iss 3, Pp 553-557 (2021)
We report on a 69-year-old man who presented with itching and erythematous papules on his torso and extremities, which were resistant to topical therapy with antibiotics and steroids. Physical examination revealed multiple erythematous papules on his
Externí odkaz:
https://doaj.org/article/4c54bedda83f4d448d61d986fa379fa4
Autor:
Jessica C. Hassel, Timo E. Schank, Heiko Smetak, Jasmin Mühlbauer, Martin Salzmann, Devayani Machiraju, Christian Menzer, Kristin Lang, Laila König, Matthias F. Haefner, Ingrid Hülsmeyer, Christian Kohler, Rainer Spang, Alexander Enk, Jürgen Debus, Philipp Beckhove
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
In patients with melanoma brain metastases (MBM), a combination of radiotherapy (RT) with immune checkpoint inhibitors (ICI) is routinely used. However, the best sequence of radio-immunotherapy (RIT) remains unclear. In an exploratory phase 2 trial,
Externí odkaz:
https://doaj.org/article/5c11e7dab9974230b5dc3d9f87c8177f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adenosine (Ado) has been shown to have immunosuppressive effects in a variety of diseases. It can either be released directly into the extracellular environment by cells, or it can be produced by degradation of ATP within the extracellular spaces. Th
Externí odkaz:
https://doaj.org/article/319e86370aea403e8d62839255f7d29c
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 9, p adv00537 (2021)
Externí odkaz:
https://doaj.org/article/3b764d32dfb14bbeb75848f55155f6e4
Autor:
Ferdinand Toberer, Holger A. Haenssle, Arno Rütten, Dmitry Kazakov, Liubov Kastnerova, Alexander Enk, Wolfgang Hartschuh, Ines Bertlich, Julia Hartmann, Martin Laimer, Wolfgang Weyers, Peter Helmbold, Heinz Kutzner
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 13, Pp 1270-1274 (2019)
To shed more light on the pathogenesis of sebaceous carcinoma, we analysed the expression of proteins related to angiogenesis in 18 ocular and 22 extraocular sebaceous carcinomas using a broad panel of immunohistochemical markers. To quantify the exp
Externí odkaz:
https://doaj.org/article/de6da8be1b7b43f48aae46a677e65739
Autor:
Katharina S. Kommoss, Julia K. Winkler, Christine Mueller-Christmann, Felicitas Bardehle, Ferdinand Toberer, Wilhelm Stolz, Teresa Kraenke, Rainer Hofmann-Wellenhof, Andreas Blum, Alexander Enk, Albert Rosenberger, Holger A. Haenssle
Publikováno v:
European Journal of Cancer. 185:53-60
Autor:
Devayani Machiraju, Melanie Wiecken, Nina Lang, Ingrid Hülsmeyer, Jasmin Roth, Timo E. Schank, Rosa Eurich, Niels Halama, Alexander Enk, Jessica C. Hassel
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Different mechanisms lead to immune checkpoint inhibitor (ICI) resistance. Identifying clinically useful biomarkers might improve drug selection and patients’ therapy. We analyzed the soluble immune checkpoints sPD1, sPDL1, sLAG3, and sTIM3 using E
Externí odkaz:
https://doaj.org/article/e6ad7a1313874ac4a737a25d7de643ea
Autor:
Ferdinand Toberer, Holger A. Haenssle, Martin Laimer, Monika Heinzel-Gutenbrunner, Alexander Enk, Wolfgang Hartschuh, Peter Helmbold, Heinz Kutzner
Publikováno v:
Acta Dermato-Venereologica, Vol 100, Iss 15, p adv00235 (2020)
This study analysed the expression of vascular endothelial growth factor-A (VEGF), VEGFR-2, and VEGFR-3 in primary cutaneous melanomas with positive and negative sentinel node status (SLN) (a total of 58 specimens divided into 2 groups of 29 for each
Externí odkaz:
https://doaj.org/article/070d2263a0c9415085176cf9b189645e