Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Alexander, Deev"'
1
Akademický článek
Abnormal EEG Effects of Acute Apomorphine Injection in 5xFAD Transgenic Mice Are Partially Normalized in Those Chronically Pretreated with Apomorphine: The Time–Frequency Clustering of EEG Spectra
Autor: Vasily Vorobyov, Alexander Deev
Publikováno v: Biomedicines, Vol 12, Iss 11, p 2433 (2024)
Background: In experimental and clinical studies of pharmacological treatments for Alzheimer’s disease (AD), the electroencephalogram (EEG) frequency spectrum approach has demonstrated its efficacy in determining the characteristics of pathological
Externí odkaz: https://doaj.org/article/164b64441cd04a36b57d574cf4cc1f2c
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2
Akademický článek
Disruption of Electroencephalogram Coherence between Cortex/Striatum and Midbrain Dopaminergic Regions in the Knock-Out Mice with Combined Loss of Alpha, Beta, and Gamma Synucleins
Autor: Vasily Vorobyov, Alexander Deev, Kirill Chaprov, Natalia Ninkina
Publikováno v: Biomedicines, Vol 12, Iss 4, p 881 (2024)
The malfunctioning of the brain synucleins is associated with pathogenesis of Parkinson’s disease. Synucleins’ ability to modulate various pre-synaptic processes suggests their modifying effects on the electroencephalogram (EEG) recorded from dif
Externí odkaz: https://doaj.org/article/cd85c9eae82b4e6dafcd5148a7aa986f
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3
Akademický článek
Early Effects of Alpha-Synuclein Depletion by Pan-Neuronal Inactivation of Encoding Gene on Electroencephalogram Coherence between Different Brain Regions in Mice
Autor: Vasily Vorobyov, Alexander Deev, Olga Morozova, Zoya Oganesyan, Anastasia M. Krayushkina, Tamara A. Ivanova, Kirill Chaprov
Publikováno v: Biomedicines, Vol 11, Iss 12, p 3282 (2023)
Inactivation of the Snca gene in young mice by chronic injections of tamoxifen (TAM), a selective estrogen receptor modifier, has been shown to decrease the level of alpha-synuclein, a key peptide in the pathogenesis of Parkinson’s disease. In youn
Externí odkaz: https://doaj.org/article/9aed2367433d495f861423801131acfe
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4
Akademický článek
Age-Related Modifications of Electroencephalogram Coherence in Mice Models of Alzheimer’s Disease and Amyotrophic Lateral Sclerosis
Autor: Vasily Vorobyov, Alexander Deev, Kirill Chaprov, Aleksey A. Ustyugov, Ekaterina Lysikova
Publikováno v: Biomedicines, Vol 11, Iss 4, p 1151 (2023)
Evident similarities in pathological features in aging and Alzheimer’s disease (AD) raise the question of a role for natural age-related adaptive mechanisms in the prevention/elimination of disturbances in interrelations between different brain are
Externí odkaz: https://doaj.org/article/acde5994bffc4b6c86d6534f816bd697
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5
Akademický článek
Loss of the Synuclein Family Members Differentially Affects Baseline- and Apomorphine-Associated EEG Determinants in Single-, Double- and Triple-Knockout Mice
Autor: Vasily Vorobyov, Alexander Deev, Iuliia Sukhanova, Olga Morozova, Zoya Oganesyan, Kirill Chaprov, Vladimir L. Buchman
Publikováno v: Biomedicines, Vol 10, Iss 12, p 3128 (2022)
Synucleins comprise a family of small proteins highly expressed in the nervous system of vertebrates and involved in various intraneuronal processes. The malfunction of alpha-synuclein is one of the key events in pathogenesis of Parkinson disease and
Externí odkaz: https://doaj.org/article/924cb432252141c9a9fb269cec4024de
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6
Baseline Electroencephalogram and Its Evolution after Activation of Dopaminergic System by Apomorphine in Middle-Aged 5XFAD Transgenic Mice, a Model of Alzheimer’s Disease
Autor: Vasily Vorobyov, Alexander Deev, Zoya Oganesyan, Frank Sengpiel, Aleksey A. Ustyugov
Publikováno v: Dynamics; Volume 2; Issue 4; Pages: 356-366
Aging and Alzheimer’s disease (AD) are characterized by common pathological features associated with alterations in neuronal connections. These inevitably affect the functioning of specific brain areas and their interrelations, leading to questions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c5983426c103edc2f53c54bd495931
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7
Cortical and Striatal Electroencephalograms and Apomorphine Effects in the FUS Mouse Model of Amyotrophic Lateral Sclerosis
Autor: Vladimir O. Nebogatikov, Frank Sengpiel, Alexander Deev, Vasily Vorobyov, Aleksey A. Ustyugov
Publikováno v: Journal of Alzheimer's disease : JAD. 81(4)
Background: Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motor neurons resulting in muscle atrophy. In contrast to the lower motor neurons, the role of upper (cortical) neurons in ALS is yet unclear. Maturation of locomotor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e22df2f24f61ef90776f1b79d7324a
https://pubmed.ncbi.nlm.nih.gov/33935079
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9
Intrahippocampal Pathways Involved in Learning/Memory Mechanisms are Affected by Intracerebral Infusions of Amyloid-β25-35 Peptide and Hydrated Fullerene C60 in Rats
Autor: Ekaterina A. Mugantseva, Rita Ya. Gordon, Vasily Vorobyov, Sergey Khutsyan, Igor Podolski, Frank Sengpiel, Arkady N. Murashev, Alexander Deev, E. I. Makarova
Publikováno v: Journal of Alzheimer's Disease. 58:711-724
Primary memory impairments associated with increased level of amyloid-beta (Аβ) in the\ud brain have been shown to be linked, partially, with early pathological changes in the\ud entorhinal cortex (EC) which spread on the whole limbic system. While
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16aedc2dc0a263b92f380f60f3733e65
https://doi.org/10.3233/jad-161182
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