Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Alexander, Burges"'
Autor:
Dhanya Ramachandran, Jonathan P. Tyrer, Stefan Kommoss, Anna DeFazio, Marjorie J. Riggan, AOCS Group, Penelope M. Webb, Peter A. Fasching, Diether Lambrechts, María J. García, Cristina Rodríguez-Antona, Marc T. Goodman, Francesmary Modugno, Kirsten B. Moysich, Beth Y. Karlan, Jenny Lester, Susanne K. Kjaer, Allan Jensen, Estrid Høgdall, Ellen L. Goode, William A. Cliby, Amanika Kumar, Chen Wang, Julie M. Cunningham, Stacey J. Winham, Alvaro N. Monteiro, Joellen M. Schildkraut, Daniel W. Cramer, Kathryn L. Terry, Linda Titus, Line Bjorge, Liv Cecilie Vestrheim Thomsen, OPAL Study Group, Tanja Pejovic, Claus K. Høgdall, Iain A. McNeish, Taymaa May, David G. Huntsman, Jacobus Pfisterer, Ulrich Canzler, Tjoung-Won Park-Simon, Willibald Schröder, Antje Belau, Lars Hanker, Philipp Harter, Jalid Sehouli, Rainer Kimmig, Nikolaus de Gregorio, Barbara Schmalfeldt, Klaus Baumann, Felix Hilpert, Alexander Burges, Boris Winterhoff, Peter Schürmann, Lisa-Marie Speith, Peter Hillemanns, Andrew Berchuck, Sharon E. Johnatty, Susan J. Ramus, Georgia Chenevix-Trench, Paul D. P. Pharoah, Thilo Dörk, Florian Heitz
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Survival from ovarian cancer depends on the resection status after primary surgery. We performed genome-wide association analyses for resection status of 7705 ovarian cancer patients, including 4954 with high-grade serous carcinoma (HGSOC),
Externí odkaz:
https://doaj.org/article/ac0253f401c44385bb41f701da028a0c
Autor:
Christina Buschmann, Laura Unverdorben, Julia Knabl, Stefan Hutter, Sarah Meister, Susanne Beyer, Maximiliane Burgmann, Lucia Keilmann, Alaleh Zati zehni, Elisa Schmoeckel, Mirjana Kessler, Udo Jeschke, Sven Mahner, Thomas Kolben, Franziska Ganster, Alexander Burges
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8840-8851 (2023)
Galectins are known to play an important role in immunoregulatory processes and autoimmune diseases. Galectin-10 is a cytoplasmic protein of human eosinophils and is involved in various eosinophilic diseases. Since increased galectin expression is al
Externí odkaz:
https://doaj.org/article/f3b37256f3df4904be4d65b037dceb5c
Autor:
Susanne Beyer, Maya Wehrmann, Sarah Meister, Fabian Trillsch, Franziska Ganster, Elisa Schmoeckel, Stefanie Corradini, Sven Mahner, Udo Jeschke, Mirjana Kessler, Alexander Burges, Thomas Kolben
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6907 (2024)
Endometrial cancer (EC) is a common gynecological cancer worldwide. Treatment has been improved in recent years; however, in advanced stages, therapeutic options are still limited. The expression of galectins is increased in several tumor types and t
Externí odkaz:
https://doaj.org/article/e35caf3d52954299b8449cde969bc793
Autor:
Fabian Trillsch, Bastian Czogalla, Fabian Kraus, Alexander Burges, Sven Mahner, Mirjana Kessler
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102484- (2023)
Summary: We present a protocol for effective biobanking of epithelial ovarian cancer organoids, considering the heterogeneous clinical presentation and high recurrence rates. Our protocol involves parallel testing of three media to identify patient-s
Externí odkaz:
https://doaj.org/article/f9bb398ae3f54e9f8255e8cc3bb51e66
Autor:
Fabian B. T. Kraus, Elena Sultova, Kathrin Heinrich, Andreas Jung, C. Benedikt Westphalen, Christina V. Tauber, Jörg Kumbrink, Martina Rudelius, Frederick Klauschen, Philipp A. Greif, Alexander König, Anca Chelariu-Raicu, Bastian Czogalla, Alexander Burges, Sven Mahner, Rachel Wuerstlein, Fabian Trillsch
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2345 (2024)
Advances in molecular tumor diagnostics have transformed cancer care. However, it remains unclear whether precision oncology has the same impact and transformative nature across all malignancies. We conducted a retrospective analysis of patients with
Externí odkaz:
https://doaj.org/article/bef91cea36b9475bbf8817dfe82ed9cb
Autor:
Susann Badmann, Doris Mayr, Elisa Schmoeckel, Anna Hester, Christina Buschmann, Susanne Beyer, Thomas Kolben, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, ta
Externí odkaz:
https://doaj.org/article/51dfe0d42da94dd1b154d81478a61c37
Autor:
Marie Forster, Rachel Wuerstlein, Alexander Koenig, Niklas Amann, Susanne Beyer, Till Kaltofen, Tom Degenhardt, Alexander Burges, Fabian Trillsch, Sven Mahner, Nadia Harbeck, Anca Chelariu-Raicu
Publikováno v:
Breast, Vol 60, Iss , Pp 214-222 (2021)
Introduction: The side effects of systemic cancer therapy and the lack of clinical data on safety and efficacy of COVID-19 vaccination in cancer patients cause uncertainty among the patients about whether to get vaccinated or not. Here, we evaluated
Externí odkaz:
https://doaj.org/article/c56b223aaf9545459022a504855c2e26
Autor:
Lisa Hiepp, Doris Mayr, Kathrin Gärtner, Elisa Schmoeckel, Frederick Klauschen, Alexander Burges, Sven Mahner, Reinhard Zeidler, Bastian Czogalla
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271630 (2022)
Targeting the tumor-associated carbonic anhydrase XII (CA XII) is considered a promising strategy to improve cancer treatment. As such progress is highly demanded for ovarian carcinomas, the present study aimed to provide deeper information about the
Externí odkaz:
https://doaj.org/article/58709cbb1658495aa75439d77b1847bb
Autor:
Yue Liao, Susann Badmann, Fabian Kraus, Nicole Elisabeth Topalov, Doris Mayr, Thomas Kolben, Anna Hester, Susanne Beyer, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla, Alexander Burges
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 882 (2023)
Past studies have confirmed that aberrant activation of the Wnt/β-catenin signaling is associated with tumorigenesis and metastasis in breast cancer, while the role of platelet-activating factor acetylhydrolase (PLA2G7/PAF-AH) in this signaling path
Externí odkaz:
https://doaj.org/article/8090015b4301495586f94e0efd72b3f6
Autor:
Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben, Alexander Burges, Sven Mahner, Fabian Trillsch, Udo Jeschke, Bastian Czogalla
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory
Externí odkaz:
https://doaj.org/article/a8ab4bea62a044918dd18ca46829d427