Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexander, Broadhead"'
Autor:
Daniel S. Lorrain, Ariana O Lorenzana, Alexander Broadhead, Christopher Baccei, Xiong Yifeng, Thomas O. Schrader, Michael M Poon, Karin J. Stebbins
Publikováno v:
ACS Medicinal Chemistry Letters. 12:155-161
The discovery of PIPE-359, a brain-penetrant and selective antagonist of the muscarinic acetylcholine receptor subtype 1 is described. Starting from a literature-reported M1 antagonist, linker replacement and structure-activity relationship investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430b568160efae9b410358b8f2bedc3b
https://doi.org/10.1021/acsmedchemlett.0c00626
https://doi.org/10.1021/acsmedchemlett.0c00626
Autor:
Thomas O, Schrader, Yifeng, Xiong, Ariana O, Lorenzana, Alexander, Broadhead, Karin J, Stebbins, Michael M, Poon, Christopher, Baccei, Daniel S, Lorrain
Publikováno v:
ACS Med Chem Lett
[Image: see text] The discovery of PIPE-359, a brain-penetrant and selective antagonist of the muscarinic acetylcholine receptor subtype 1 is described. Starting from a literature-reported M(1) antagonist, linker replacement and structure–activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fa8ec81843f4909dda2e384fce0b703
https://pubmed.ncbi.nlm.nih.gov/33488977
https://pubmed.ncbi.nlm.nih.gov/33488977
Autor:
Daniel S. Lorrain, Yen Pham Truong, Sailen Barik, Brian Andrew Stearns, Jill Melissa Scott, Karin J. Stebbins, Hutchinson John H, Alexander Broadhead, Alla Musiyenko, Jilly F. Evans, Peppi Prasit
Publikováno v:
International archives of allergy and immunology. 157(3)
Background: Allergic conjunctivitis is characterized by itchy, watery and swollen eyes which occur in response to exposure to seasonal or environmental allergens. The early phase reaction of allergic conjunctivitis is primarily mediated by mast cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99956515091317d39d9367e48ba616be
https://pubmed.ncbi.nlm.nih.gov/22042170
https://pubmed.ncbi.nlm.nih.gov/22042170
Autor:
Daniel S. Lorrain, Nicholas Simon Stock, Jilly F. Evans, Alexander Broadhead, Heather Coate, Karin J. Stebbins
Publikováno v:
C21. MECHANISMS OF TH2 INFLAMMATION IN THE LUNG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d2c31e92997b1c43522ff130eb3989
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4047
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4047
Autor:
Gretchen Bain, Jilly F. Evans, P Fagan, Angelina M. Santini, Alexander Broadhead, B Stearns, P Prodonovich, Christopher Baccei, Y Troung, Daniel S. Lorrain, Christopher D. King, J Scott, Karin J. Stebbins
Publikováno v:
D30. THE ROLE OF INFLAMMATION IN CHRONIC INTERSTITIAL LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4bbeae092f1a26dbbefb95877d9c09
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5658
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5658
Publikováno v:
ACM Multimedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99dbad40b932e034fa14065879d342e7
https://doi.org/10.1145/217279.215314
https://doi.org/10.1145/217279.215314