Zobrazeno 1 - 10
of 572
pro vyhledávání: '"Alexandar Tzankov"'
Autor:
Sandra Pinton, Elena Vacchi, Giacomo Chiaro, Andrea Raimondi, Alexandar Tzankov, Bernhard Gerber, Claudio Gobbi, Alain Kaelin‐Lang, Giorgia Melli
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 12, Pp 2347-2359 (2023)
Abstract Objective Disease‐modifying therapies are available for amyloidosis but are ineffective if end‐organ damage is severe. As small fiber neuropathy is an early and common feature of amyloidosis, we assessed detection and typing yield of ski
Externí odkaz:
https://doaj.org/article/e6dc7f2519654a5da7e84dcf5fc5eff2
Autor:
Barbara Bassani, Giorgia Simonetti, Valeria Cancila, Antonio Fiorino, Marilena Ciciarello, Annamaria Piva, Arman Mandegar Khorasani, Claudia Chiodoni, Daniele Lecis, Alessandro Gulino, Eugenio Fonzi, Laura Botti, Paola Portararo, Massimo Costanza, Marta Brambilla, Giorgia Colombo, Juerg Schwaller, Alexandar Tzankov, Maurilio Ponzoni, Fabio Ciceri, Niccolò Bolli, Antonio Curti, Claudio Tripodo, Mario P. Colombo, Sabina Sangaletti
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113794- (2024)
Summary: Acute myeloid leukemia (AML) progression is influenced by immune suppression induced by leukemia cells. ZEB1, a critical transcription factor in epithelial-to-mesenchymal transition, demonstrates immune regulatory functions in AML. Silencing
Externí odkaz:
https://doaj.org/article/da7ae959a4304ef9b858b1b572ed0a44
Autor:
Sabina Sahanic, Richard Hilbe, Christina Dünser, Piotr Tymoszuk, Judith Löffler-Ragg, Dietmar Rieder, Zlatko Trajanoski, Anne Krogsdam, Egon Demetz, Maria Yurchenko, Christine Fischer, Michael Schirmer, Markus Theurl, Daniela Lener, Jakob Hirsch, Johannes Holfeld, Can Gollmann-Tepeköylü, Carl P. Zinner, Alexandar Tzankov, Shen-Ying Zhang, Jean-Laurent Casanova, Wilfried Posch, Doris Wilflingseder, Guenter Weiss, Ivan Tancevski
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21893- (2023)
Background: Toll-like receptors (TLRs) play a pivotal role in the immunologic response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Exaggerated inflammatory response of innate immune cells, however, may drive morbidity a
Externí odkaz:
https://doaj.org/article/b479cdcafed844cf82d56244de04c06b
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
mRNA-based vaccines against SARS-CoV-2 have been proven to be very efficient in preventing severe COVID-19. Temporary lymphadenopathy (LA) has been observed as a common adverse event following immunization. Here we describe a case series of three fem
Externí odkaz:
https://doaj.org/article/a223154a4fea4290b1e87ae3f8464393
Autor:
Christoph Mamot, Andreas Wicki, Ursula Hasler-Strub, Salome Riniker, Qiyu Li, Lisa Holer, Daniela Bärtschi, Khalil Zaman, Roger von Moos, Konstantin J. Dedes, Laura A. Boos, Urban Novak, Alexandre Bodmer, Reto Ritschard, Ellen C. Obermann, Alexandar Tzankov, Christoph Ackermann, Véronique Membrez-Antonioli, Ursina Zürrer-Härdi, Clemens B. Caspar, Stefanie Deuster, Martin Senn, Ralph Winterhalder, Christoph Rochlitz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Advanced triple negative breast cancer (TNBC) is an aggressive, but initially chemo-sensitive disease. The prognosis is poor and more than three quarters of patients experience progression 12 months after the initiation of conventional first
Externí odkaz:
https://doaj.org/article/1eb3fffffd304a00942ffdd17ebd7e8a
Autor:
Mohamed S. Sarhan, Christina Wurst, Alexandar Tzankov, Andreas J. Bircher, Holger Wittig, Thomas Briellmann, Marc Augsburger, Gerhard Hotz, Albert Zink, Frank Maixner
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background In 1975, the mummified body of a female has been found in the Franciscan church in Basel, Switzerland. Molecular and genealogic analyses unveiled her identity as Anna Catharina Bischoff (ACB), a member of the upper class of post-r
Externí odkaz:
https://doaj.org/article/22f84288cdaf4229a2389ce37c2a102e
Autor:
Felix Nägele, Michael Graber, Jakob Hirsch, Leo Pölzl, Sabina Sahanic, Manuel Fiegl, Dominik Hau, Clemens Engler, Sophia Lechner, Anna Katharina Stalder, Kirsten D. Mertz, Jasmin D. Haslbauer, Alexandar Tzankov, Michael Grimm, Ivan Tancevski, Johannes Holfeld, Can Gollmann-Tepeköylü
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-8 (2022)
Nägele, Graber et al. evaluate cardiac manifestations of SARS-CoV-2 in patients with structural heart disease. The authors find that detection of SARS-CoV-2 in heart tissue is associated with poorer survival.
Externí odkaz:
https://doaj.org/article/33ebeb2a21ee4478ab65a2417832bd4d
Autor:
Manina M. Etter, Tomás A. Martins, Laila Kulsvehagen, Elisabeth Pössnecker, Wandrille Duchemin, Sabrina Hogan, Gretel Sanabria-Diaz, Jannis Müller, Alessio Chiappini, Jonathan Rychen, Noëmi Eberhard, Raphael Guzman, Luigi Mariani, Lester Melie-Garcia, Emanuela Keller, Ilijas Jelcic, Hans Pargger, Martin Siegemund, Jens Kuhle, Johanna Oechtering, Caroline Eich, Alexandar Tzankov, Matthias S. Matter, Sarp Uzun, Özgür Yaldizli, Johanna M. Lieb, Marios-Nikos Psychogios, Karoline Leuzinger, Hans H. Hirsch, Cristina Granziera, Anne-Katrin Pröbstel, Gregor Hutter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Both acute and chronic COVID-19 disease (also known as long-COVID) may affect the central nervous system. Here authors characterize the immunological profile of peripheral blood and cerebrospinal fluid of COVID-19 patients in order to identify the ma
Externí odkaz:
https://doaj.org/article/f0470cc90c504832a493429d193b5b41
Autor:
Michael Medinger, Till Junker, Dominik Heim, Alexandar Tzankov, Philip M. Jermann, Maria Bobadilla, Michele Vigolo, Rajwinder Lehal, Florian D. Vogl, Michael Bauer, Jakob Passweg
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 1009-1012 (2022)
Abstract Relapsed T cell acute lymphoblastic leukaemia (T‐ALL) has a very poor prognosis. A 24‐year‐old patient with relapsed high‐risk T‐ALL (PTEN gene deletion; NOTCH1 mutation), was treated with the NOTCH inhibitor CB‐103. Within 1 wee
Externí odkaz:
https://doaj.org/article/06e153db5bae43668267f8a8964d3c11
Autor:
Birgit Burkhardt, Ulf Michgehl, Jonas Rohde, Tabea Erdmann, Philipp Berning, Katrin Reutter, Marius Rohde, Arndt Borkhardt, Thomas Burmeister, Sandeep Dave, Alexandar Tzankov, Martin Dugas, Sarah Sandmann, Falko Fend, Jasmin Finger, Stephanie Mueller, Nicola Gökbuget, Torsten Haferlach, Wolfgang Kern, Wolfgang Hartmann, Wolfram Klapper, Ilske Oschlies, Julia Richter, Udo Kontny, Mathias Lutz, Britta Maecker-Kolhoff, German Ott, Andreas Rosenwald, Reiner Siebert, Arend von Stackelberg, Brigitte Strahm, Wilhelm Woessmann, Martin Zimmermann, Myroslav Zapukhlyak, Michael Grau, Georg Lenz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Survival outcomes in Burkitt lymphoma differ between adult and paediatric patients. Here, the authors show differences in mutational frequencies between age groups, and a transition between mutational profiles which occurs between 25 and 40 years.
Externí odkaz:
https://doaj.org/article/23e93bbbffce48e295f023de9062df49