Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexa Torrens"'
Autor:
Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Veronica Elizabeth Slaven, Daniele Piomelli, Michael R Bruchas, Nephi Stella, Benjamin Bruce Land
Publikováno v:
eLife, Vol 12 (2024)
No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ9-tetrahydrocannabinol (THC) and its intoxicating effects, mainly owing to the aversive response of rodents to THC that limits intake. Here,
Externí odkaz:
https://doaj.org/article/9d61c7ccc6e64534a8fdd33d9d8ebddb
Autor:
Hye-Lim Lee, Kwang-Mook Jung, Yannick Fotio, Erica Squire, Francesca Palese, Lin Lin, Alexa Torrens, Faizy Ahmed, Alex Mabou Tagne, Jade Ramirez, Shiqi Su, Christina Renee Wong, Daniel Hojin Jung, Vanessa M. Scarfone, Pauline U. Nguyen, Marcelo Wood, Kim Green, Daniele Piomelli
Publikováno v:
Biological Psychiatry. 92:845-860
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37741734f2bcaf1865c09aeab0f5e6be
https://doi.org/10.1016/j.biopsych.2022.04.017
https://doi.org/10.1016/j.biopsych.2022.04.017
Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats
Autor:
Alexa Torrens, Pritam Roy, Lin Lin, Cindy Vu, Dakota Grimes, Victoria C. Inshishian, Johanna S. Montesinos, Faizy Ahmed, Stephen V. Mahler, Marylin A. Huestis, Aditi Das, Daniele Piomelli
Publikováno v:
Cannabis and Cannabinoid Research. 7:814-826
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ad06c4e13225b47dd013221e6741b62
https://doi.org/10.1089/can.2021.0205
https://doi.org/10.1089/can.2021.0205
Autor:
Lin Lin, Alex Mabou Tagne, Erica N. Squire, Hye-Lim Lee, Yannick Fotio, Jade Ramirez, Mimi Zheng, Alexa Torrens, Faizy Ahmed, Raul Ramos, Maksim V. Plikus, Daniele Piomelli
Publikováno v:
Pharmacology. 107:423-432
Introduction: Previous work suggests the existence of a paracrine signaling mechanism in which histamine released from visceral mast cells into the portal circulation contributes to fasting-induced ketogenesis by stimulating biosynthesis of the endog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc6881a1fcaf0d7614e54aaef77d2b0
https://doi.org/10.1159/000524753
https://doi.org/10.1159/000524753
Autor:
Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Slaven, Danielle Piomelli, Michael Bruchas, Nephi Stella, Benjamin Land
BackgroundNo preclinical approach enables the study of voluntary oral consumption of high dose Δ9-tetrahydrocannabinol (THC) and its intoxicating effects, mainly owing to the aversive response of rodents to THC that limits intake. Here we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadb71f2e776011e94f5e96164bafcf1
https://doi.org/10.1101/2022.11.23.517743
https://doi.org/10.1101/2022.11.23.517743
Autor:
Faizy Ahmed, Alexa Torrens, Stephen V. Mahler, Francesca Ferlenghi, Marilyn A. Huestis, Daniele Piomelli
Publikováno v:
Cannabis and cannabinoid research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56981187cb88355f81f3976748827f8
https://pubmed.ncbi.nlm.nih.gov/36367975
https://pubmed.ncbi.nlm.nih.gov/36367975
Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism
Autor:
Francesca Palese, Silvia Pontis, Natalia Realini, Alexa Torrens, Faizy Ahmed, Francesca Assogna, Clelia Pellicano, Paola Bossù, Gianfranco Spalletta, Kim Green, Daniele Piomelli
The lysosomal cysteine hydrolase N-acylethanolamine acid amidase (NAAA) deactivates palmitoylethanolamide (PEA), a lipid-derived PPAR-α agonist that is critically involved in the control of pain and inflammation. In this study, we asked whether NAAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4cf31b9d60651925f999bf11092cf1
https://escholarship.org/uc/item/9jx4m954
https://escholarship.org/uc/item/9jx4m954
Autor:
Lin Lin, Kwang-Mook Jung, Johnny Le, Georgia Colleluori, Courtney Wood, Hye-Lim Lee, Francesca Palese, Erica Squire, Shiqi Su, Alexa Torrens, Yannick Fotio, Lingyi Tang, Clinton Yu, Qin Yang, Lan Huang, Nicholas DiPatrizio, Cholsoon Jang, Saverio Cinti, Daniele Piomelli
SUMMARYOne of cannabis’ most iconic effects is the stimulation of hedonic high-calorie eating – the ‘munchies’ – yet habitual cannabis users are on average leaner than non-users. We asked whether this unexpected phenotype might result from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3143ecc86887dda2d68ce8bafd5936d
https://doi.org/10.1101/2022.07.26.501615
https://doi.org/10.1101/2022.07.26.501615
Autor:
Erik Castillo, Jenny Cevallos, Vivek Swarup, Alexa Torrens, Marilyn A. Huestis, Victoria C. Inshishian, Stephen V. Mahler, Christina R Perrone, Drew N Justeson, Christina M. Ruiz, Daniele Piomelli, Eden V Harder
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 46, iss 5
Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is responsible for the drug's reinforcing effects. Retrospective human studies suggest that cannabis use during adolescence is linked to long-term negative psychological o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7d107fb1708e16517993a1f7ed0013
https://doi.org/10.1038/s41386-020-00839-w
https://doi.org/10.1038/s41386-020-00839-w
Autor:
Brandon McNeil, Hannah C. Huff, Aditi Das, Faizy Ahmed, Marilyn A. Huestis, Stephen V. Mahler, Valentina Vozella, Daniele Piomelli, Alexa Torrens, Andrea Ghidini
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 374:151-160
We investigated the pharmacokinetic properties of Δ9-tetrahydrocannabinol (Δ9-THC), the main psychoactive constituent of cannabis, in adolescent and adult male mice. The drug was administered at logarithmically ascending doses (0.5, 1.6, and 5 mg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd28fd1eabf2e8098d2397f411638bdf
https://doi.org/10.1124/jpet.120.265892
https://doi.org/10.1124/jpet.120.265892