Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alexa S Green"'
Autor:
Nicolas Chapuis, Jérôme Tamburini, Pascale Cornillet-Lefebvre, Lucile Gillot, Valérie Bardet, Lise Willems, Sophie Park, Alexa S Green, Norbert Ifrah, François Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary
Publikováno v:
Haematologica, Vol 95, Iss 3 (2010)
Background Alterations in the PI3K/Akt pathway are found in a wide range of cancers and the development of PI3K inhibitors represents a promising approach to cancer therapy. Constitutive PI3K activation, reflecting an intrinsic oncogenic deregulation
Externí odkaz:
https://doaj.org/article/17b59fa7bac44ca5aee0d8cb24e6b317
Autor:
Didier Bouscary, Patrick Mayeux, Catherine Lacombe, Olivier Herault, François Dreyfus, Norbert Ifrah, Sauveur-Michel Maira, Alexandre Macone, Sophie Park, Lise Willems, Melanie Pannetier, Aymeric Neyret, Valerie Bardet, Christine Vignon, Alexa S. Green, Jerome Tamburini, Nicolas Chapuis
PDF file - 202K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a75bf83c5a432bdf3d9918dbdd1fff
https://doi.org/10.1158/1078-0432.22442987.v1
https://doi.org/10.1158/1078-0432.22442987.v1
Autor:
Didier Bouscary, Patrick Mayeux, Catherine Lacombe, Olivier Herault, François Dreyfus, Norbert Ifrah, Sauveur-Michel Maira, Alexandre Macone, Sophie Park, Lise Willems, Melanie Pannetier, Aymeric Neyret, Valerie Bardet, Christine Vignon, Alexa S. Green, Jerome Tamburini, Nicolas Chapuis
Purpose: The growth and survival of acute myeloid leukemia (AML) cells are enhanced by the deregulation of signaling pathways such as phosphoinositide 3-kinase (PI3K)/Akt and mammalian target of rapamycin (mTOR). Major efforts have thus been made to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24799f586683fe17e00df5e3695874ef
https://doi.org/10.1158/1078-0432.c.6519605
https://doi.org/10.1158/1078-0432.c.6519605
Autor:
Didier Bouscary, Patrick Mayeux, Catherine Lacombe, Olivier Herault, François Dreyfus, Norbert Ifrah, Sauveur-Michel Maira, Alexandre Macone, Sophie Park, Lise Willems, Melanie Pannetier, Aymeric Neyret, Valerie Bardet, Christine Vignon, Alexa S. Green, Jerome Tamburini, Nicolas Chapuis
PDF file - 109K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c898ce38fcd7e7bdc69c1f6e895f1de
https://doi.org/10.1158/1078-0432.22442990.v1
https://doi.org/10.1158/1078-0432.22442990.v1
Autor:
Pierre Sujobert, Laury Poulain, Etienne Paubelle, Florence Zylbersztejn, Adrien Grenier, Mireille Lambert, Elizabeth C. Townsend, Jean-Marie Brusq, Edwige Nicodeme, Justine Decrooqc, Ina Nepstad, Alexa S. Green, Johanna Mondesir, Marie-Anne Hospital, Nathalie Jacque, Alexandra Christodoulou, Tiffany A. Desouza, Olivier Hermine, Marc Foretz, Benoit Viollet, Catherine Lacombe, Patrick Mayeux, David M. Weinstock, Ivan C. Moura, Didier Bouscary, Jerome Tamburini
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1446-1457 (2015)
AMPK is a master regulator of cellular metabolism that exerts either oncogenic or tumor suppressor activity depending on context. Here, we report that the specific AMPK agonist GSK621 selectively kills acute myeloid leukemia (AML) cells but spares no
Externí odkaz:
https://doaj.org/article/9222733afbf84f689b27bbb06ca36d9b
Autor:
Noémie Lang, Alexa S. Green
Publikováno v:
Blood. 138(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b148b06d795387799dfa91212e4cd53b
https://pubmed.ncbi.nlm.nih.gov/34792570
https://pubmed.ncbi.nlm.nih.gov/34792570
Autor:
Didier Bouscary, Charles Dussiau, Sylvain Barreau, Alexa S. Green, Valérie Bardet, Lise Willems, Nicolas Chapuis, Stephanie Mathis, Michaela Fontenay, Anna Raimbault, Anne-Sophie Alary, Olivier Kosmider
Publikováno v:
Cytometry Part B: Clinical Cytometry
Cytometry Part B: Clinical Cytometry, Wiley, 2020, 98 (3), pp.226-237. ⟨10.1002/cyto.b.21843⟩
Cytometry Part B: Clinical Cytometry, Wiley, 2020, 98 (3), pp.226-237. ⟨10.1002/cyto.b.21843⟩
International audience; Background: Multiparametric flow cytometry (MFC) was recently reported to be a helpful additional tool in the diagnosis of myelodysplastic syndromes (MDS). However, numerous aberrancies have been reported that makes their eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c3cb60e7d6df3304081c4a00d1eed2
https://hal.archives-ouvertes.fr/hal-03227850
https://hal.archives-ouvertes.fr/hal-03227850
Autor:
Nicolas Chapuis, Alexa S. Green
Publikováno v:
Blood. 131(4)
[Figure][1] A 44-year-old woman was referred for asthenia. Laboratory evaluation showed normocytic anemia (2.2 g/dL hemoglobin, mean corpuscular volume [MCV] of 82 fL, 9.18 × 109/L reticulocytes) with an increased red cell distribution width (RDW, 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fba08a3ddb6fefa5ff13f73cb4ed18
https://pubmed.ncbi.nlm.nih.gov/29371209
https://pubmed.ncbi.nlm.nih.gov/29371209
Autor:
Marie-Anne Hospital, Alexa S Green, Thiago T Maciel, Ivan C Moura, Anskar Y Leung, Didier Bouscary, Jerome Tamburini
Publikováno v:
OncoTargets and therapy
Acute myeloid leukemia (AML) is an aggressive hematopoietic malignancy that is cured in as few as 15%-40% of cases. Tremendous improvements in AML prognostication arose from a comprehensive analysis of leukemia cell genomes. Among normal karyotype AM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed29577a1d4776edf65f3a99c8961428
https://pubmed.ncbi.nlm.nih.gov/28223820
https://pubmed.ncbi.nlm.nih.gov/28223820
Autor:
Christian Recher, Christine Dozier, L L Yuan, Alexa S. Green, Stéphane Manenti, F Grimal, Christine Didier, V Mansat-De Mas, Jerome Tamburini, Sarah Bertoli
Publikováno v:
Leukemia. 28:293-301
Phosphorylation by Akt on Ser 280 was reported to induce cytoplasmic retention and inactivation of CHK1 with consequent genetic instability in PTEN-/- cells. In acute myeloid leukemia cells carrying the FLT3-internal tandem duplication (ITD) mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dec4d3f8f33dafbfdaf8822e45acd3
https://doi.org/10.1038/leu.2013.168
https://doi.org/10.1038/leu.2013.168