Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexa Price-Whelan"'
Autor:
Lindsey C. Florek, Xi Lin, Yu-Cheng Lin, Min-Han Lin, Arijit Chakraborty, Alexa Price-Whelan, Liang Tong, Laurence Rahme, Lars E. P. Dietrich
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that thrives in environments associated with human activity, including soil and water altered by agriculture or pollution. Because L-lactate is a significant product of plant and animal met
Externí odkaz:
https://doaj.org/article/f74e82df9c1749108a18d44213d969b4
Autor:
Hannah Dayton, Julie Kiss, Mian Wei, Shradha Chauhan, Emily LaMarre, William Cole Cornell, Chase J Morgan, Anuradha Janakiraman, Wei Min, Raju Tomer, Alexa Price-Whelan, Jasmine A Nirody, Lars E P Dietrich
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002205 (2024)
Cells must access resources to survive, and the anatomy of multicellular structures influences this access. In diverse multicellular eukaryotes, resources are provided by internal conduits that allow substances to travel more readily through tissue t
Externí odkaz:
https://doaj.org/article/140612b2aa004b1588d5a48fc35156a8
Autor:
Marina K. Smiley, Doran C. Sekaran, Farhad Forouhar, Erica Wolin, Marko Jovanovic, Alexa Price-Whelan, Lars E. P. Dietrich
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTPseudomonas aeruginosa is a common, biofilm-forming pathogen that exhibits complex pathways of redox metabolism. It produces four different types of terminal oxidases for aerobic respiration, and for one of these, the cbb3-type terminal oxida
Externí odkaz:
https://doaj.org/article/4a07177092234f258dfdd440a564d381
Autor:
Lisa Juliane Kahl, Kelly N. Eckartt, Diana K. Morales, Alexa Price-Whelan, Lars E. P. Dietrich
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Sunlight drives phototrophic metabolism, which affects redox conditions and produces substrates for nonphototrophs. These environmental parameters fluctuate daily due to Earth’s rotation, and nonphototrophic organisms can therefore benefit
Externí odkaz:
https://doaj.org/article/022fc042e6ef4b0099ebb2eb6fd3a1d7
Autor:
Bryan Wang, Yu-Cheng Lin, Alejandro Vasquez-Rifo, Jeanyoung Jo, Alexa Price-Whelan, Shujuan Tao McDonald, Lewis M. Brown, Christian Sieben, Lars E. P. Dietrich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
R-bodies are long, extendable protein polymers formed in the cytoplasm of some bacteria. Here, Wang et al. show that Pseudomonas aeruginosa produces R-bodies during colonization of plant and nematode hosts, and R-bodies induce ribosome cleavage and t
Externí odkaz:
https://doaj.org/article/e62ad031b3894821b3d96bbb38aba300
Autor:
Francisco Díaz-Pascual, Martin Lempp, Kazuki Nosho, Hannah Jeckel, Jeanyoung K Jo, Konstantin Neuhaus, Raimo Hartmann, Eric Jelli, Mads Frederik Hansen, Alexa Price-Whelan, Lars EP Dietrich, Hannes Link, Knut Drescher
Publikováno v:
eLife, Vol 10 (2021)
Bacteria commonly live in spatially structured biofilm assemblages, which are encased by an extracellular matrix. Metabolic activity of the cells inside biofilms causes gradients in local environmental conditions, which leads to the emergence of phys
Externí odkaz:
https://doaj.org/article/c7189e6f7875449c8818c4fcab0a0457
Autor:
George A. O’Toole, Aurélie Crabbé, Rolf Kümmerli, John J. LiPuma, Jennifer M. Bomberger, Jane C. Davies, Dominique Limoli, Vanessa V. Phelan, James B. Bliska, William H. DePas, Lars E. Dietrich, Thomas H. Hampton, Ryan Hunter, Cezar M. Khursigara, Alexa Price-Whelan, Alix Ashare, Robert A. Cramer, Joanna B. Goldberg, Freya Harrison, Deborah A. Hogan, Michael A. Henson, Dean R. Madden, Jared R. Mayers, Carey Nadell, Dianne Newman, Alice Prince, Damian W. Rivett, Joseph D. Schwartzman, Daniel Schultz, Donald C. Sheppard, Alan R. Smyth, Melanie A. Spero, Bruce A. Stanton, Paul E. Turner, Chris van der Gast, Fiona J. Whelan, Rachel Whitaker, Katrine Whiteson
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
A recent workshop titled “Developing Models to Study Polymicrobial Infections,” sponsored by the Dartmouth Cystic Fibrosis Center (DartCF), explored the development of new models to study the polymicrobial infections associated with the airways o
Externí odkaz:
https://doaj.org/article/1ed07d7593e74bbf8897df772ce78eb2
Autor:
Konstanze T. Schiessl, Fanghao Hu, Jeanyoung Jo, Sakila Z. Nazia, Bryan Wang, Alexa Price-Whelan, Wei Min, Lars E. P. Dietrich
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Pseudomonas aeruginosa releases redox-active metabolites called phenazines. Here, the authors use metabolic imaging by stimulated Raman scattering microscopy to show that phenazines antagonize the effects of antibiotics on P. aeruginosa biofilms by m
Externí odkaz:
https://doaj.org/article/391da8e46f344a68bdd44bdb1155726c
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Pseudomonas aeruginosa is the most common cause of chronic, biofilm-based lung infections in patients with cystic fibrosis (CF). Sputum from patients with CF has been shown to contain oxic and hypoxic subzones as well as millimolar concentra
Externí odkaz:
https://doaj.org/article/c2647300575847f4a1529a39cec518a7
Autor:
Daniel L. Bellin, Hassan Sakhtah, Yihan Zhang, Alexa Price-Whelan, Lars E. P. Dietrich, Kenneth L. Shepard
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Much remains to be understood about the biochemical basis of microbial community behaviour in biofilms. Here the authors describe a novel electrochemical camera chip that allows simultaneous spatial imaging of multiple metabolites that are crucial to
Externí odkaz:
https://doaj.org/article/35c7f97a5c614c5ca129302d97ef7b03