Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexa M. Salsbury"'
Autor:
Justin A. Lemkul, Alexa M. Salsbury
Publikováno v:
Curr Opin Struct Biol
Nucleic acids play critical roles in carrying genetic information, participating in catalysis, and preserving chromosomal structure. Despite over a century of study, efforts to understand the dynamics and structure-function relationships of DNA and R
Publikováno v:
Journal of Chemical Information and Modeling. 60:6476-6488
G-quadruplexes (GQs) are topologically diverse, highly thermostable noncanonical nucleic acid structures that form in guanine-rich sequences in DNA and RNA. GQs are implicated in transcriptional and translational regulation and genome maintenance, an
Publikováno v:
J Chem Theory Comput
G-quadruplexes (GQs) are highly ordered nucleic acid structures that play fundamental roles in regulating gene expression and maintaining genomic stability. GQs are topologically diverse and enriched in promoter sequences of growth regulatory genes a
Publikováno v:
J Chem Inf Model
G-quadruplexes (GQs) are topologically diverse, highly thermostable noncanonical nucleic acid structures that form in guanine-rich sequences in DNA and RNA. GQs are implicated in transcriptional and translational regulation and genome maintenance, an
Autor:
Alexa M. Salsbury, Justin A. Lemkul
Publikováno v:
Biophysical journal. 120(11)
Nucleic acid-ion interactions are fundamentally important to the physical, energetic, and conformational properties of DNA and RNA. These interactions help fold and stabilize highly ordered secondary and tertiary structures, such as G-quadruplexes (G
Publikováno v:
Biophysical Journal. 120:222a-223a
Publikováno v:
PEARC
Research in life science domains is producing larger data sets that require the use of computational approaches to understand biological phenomena. Academic institutions, industry, and other sectors in the life sciences are creating jobs that involve
Publikováno v:
Biophysical Journal. 118:65a
Publikováno v:
Biophysical Journal. 118:224a