Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexa K Dowdell"'
Autor:
Gwen Kramer, Tiffany Blair, Shelly Bambina, Aanchal Preet Kaur, Alejandro Alice, Jason Baird, David Friedman, Alexa K. Dowdell, Michio Tomura, Clemens Grassberger, Brian D. Piening, Marka R. Crittenden, Michael J. Gough
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract T cells recirculate through tissues and lymphatic organs to scan for their cognate antigen. Radiation therapy provides site-specific cytotoxicity to kill cancer cells but also has the potential to eliminate the tumor-specific T cells in fiel
Externí odkaz:
https://doaj.org/article/921a05abf75b46bca345c3b931ab641e
Autor:
Raed M. Alsulaiman, Abdulaziz A. Al-Quorain, Fahad A. Al-Muhanna, Stanley Piotrowski, Ezzeddin A. Kurdi, Chittibabu Vatte, Ahmed A. Alquorain, Noorah H. Alfaraj, Abdulaziz M. Alrezuk, Fred Robinson, Alexa K. Dowdell, Turki A. Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla, Brendan J. Keating, Ryan Meng, Brian Piening, Amein K. Al-Ali
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Crohn’s diseases and ulcerative colitis, both of which are chronic immune-mediated disorders of the gastrointestinal tract are major contributors to the overarching Inflammatory bowel diseases. It has become increasingly evident
Externí odkaz:
https://doaj.org/article/32fc2a65bec745edb3b8c9007db92ce6
Autor:
Terry R. Medler, Tiffany C. Blair, Alejandro F. Alice, Alexa K. Dowdell, Brian D. Piening, Marka R. Crittenden, Michael J. Gough
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Radiation therapy induces immunogenic cell death in cancer cells, whereby released endogenous adjuvants are sensed by immune cells to direct adaptive immune responses. TLRs expressed on several immune subtypes recognize innate adjuvants to d
Externí odkaz:
https://doaj.org/article/749dcd8729de41a6a451e3c2da813f94
Autor:
Fahad A. Al-Muhanna, Alexa K. Dowdell, Abdulmohsen H. Al Eleq, Waleed I. Albaker, Andrew W. Brooks, Ali I. Al-Sultan, Abdullah M. Al-Rubaish, Khaled R. Alkharsah, Raed M. Sulaiman, Abdulaziz A. Al-Quorain, Cyril Cyrus, Rudaynah A. Alali, Chittibabu Vatte, Fred L. Robinson, Xin Zhou, Michael P. Snyder, Afnan F. Almuhanna, Brendan J. Keating, Brian D. Piening, Amein K. Al-Ali
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Large-scale gut microbiome sequencing has revealed key links between microbiome dysfunction and metabolic diseases such as type 2 diabetes (T2D). To date, these efforts have largely focused on Western populations, with few studies
Externí odkaz:
https://doaj.org/article/c8190e3aa79d4cf3b11d0c5dd6c1129f
Autor:
Brian D. Piening, Alexa K. Dowdell, Mengqi Zhang, Bao-Li Loza, David Walls, Hui Gao, Maede Mohebnasab, Yun Rose Li, Eric Elftmann, Eric Wei, Divya Gandla, Hetal Lad, Hassan Chaib, Nancy K. Sweitzer, Mario Deng, Alexandre C. Pereira, Martin Cadeiras, Abraham Shaked, Michael P. Snyder, Brendan J. Keating
Publikováno v:
J Heart Lung Transplant
BACKGROUND: Heart transplantation provides a significant improvement in survival and quality of life for patients with end-stage heart disease, however many recipients experience different levels of graft rejection that can be associated with signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b12a3f287639ff47937c954016969a
https://doi.org/10.1016/j.healun.2022.01.1377
https://doi.org/10.1016/j.healun.2022.01.1377
Autor:
Aanchal Preet Kaur, Terry R. Medler, Tiffany C. Blair, Alejandro F. Alice, Megan R. Ball, Alexa K. Dowdell, Brian D. Piening, Marka R. Crittenden, Michael J. Gough
Publikováno v:
Cancer Research. 83:6410-6410
The balance of innate signaling through adaptor proteins such as MyD88 and TRIF is critical in directing the pattern of inflammatory responses following exposure to endogenous adjuvants. While innate stimuli can cause inflammation that supports adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2443e0cbd65b3f37ddc2b581fb02b213
https://doi.org/10.1158/1538-7445.am2023-6410
https://doi.org/10.1158/1538-7445.am2023-6410
Autor:
Tawaun A. Lucas, Marion S. Buckwalter, Michael Snyder, Eric X Wei, Kendra J. Lechtenberg, Brian D. Piening, Todd C. Peterson, Alexa K Dowdell, Hassan Chaib
Publikováno v:
Translational Stroke Research. 12:331-346
Obesity is associated with chronic peripheral inflammation, is a risk factor for stroke, and causes increased infarct sizes. To characterize how obesity increases infarct size, we fed a high-fat diet to wild-type C57BL/6J mice for either 6 weeks or 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b160ded21cb5637982f6c0088881cf69
https://doi.org/10.1007/s12975-020-00826-9
https://doi.org/10.1007/s12975-020-00826-9
Publikováno v:
Natural Products in Obesity and Diabetes ISBN: 9783030921958
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c026a83eedd6abfd9c3c5c4c2723be0f
https://doi.org/10.1007/978-3-030-92196-5_2
https://doi.org/10.1007/978-3-030-92196-5_2
Autor:
Tiffany C Blair, Shelly Bambina, Gwen F Kramer, Alexa K Dowdell, Alejandro F Alice, Jason R Baird, Amanda W Lund, Brian D Piening, Marka R Crittenden, Michael J Gough
Publikováno v:
Life science alliance. 5(9)
Radiation therapy generates extensive cancer cell death capable of promoting tumor-specific immunity. Within the tumor, conventional dendritic cells (cDCs) are known to carry tumor-associated antigens to the draining lymph node (TdLN) where they init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486eac7ebe82fa2e1d51cd14271d0118
https://pubmed.ncbi.nlm.nih.gov/35487695
https://pubmed.ncbi.nlm.nih.gov/35487695
Autor:
Brian Piening, Alexa K. Dowdell, Ryan Meng, Ann Vita, Roshanthi K. Weerasinghe, Alisha Stein, Bela Bapat, Brock Schroeder, Shu-Ching Chang, Lauren Harold, Mark Schmidt, Thomas Ward, Josiah Wagner, Stanley Piotrowski, Phillip G. Febbo, Carlo Bruno Bifulco
Publikováno v:
Journal of Clinical Oncology. 40:3078-3078
3078 Background: Gene fusions caused by chromosomal rearrangements comprise a key category of oncogenic driver mutations. However, given the diverse array of potentially novel loci where each proto-oncogene can translocate, many assays including DNA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1544b457868f95f4fb18f52ed1577efb
https://doi.org/10.1200/jco.2022.40.16_suppl.3078
https://doi.org/10.1200/jco.2022.40.16_suppl.3078