Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexa J. Roeder"'
Autor:
Douglas F. Lake, Alexa J. Roeder, Maria J. Gonzalez-Moa, Megan Koehler, Erin Kaleta, Paniz Jasbi, John Vanderhoof, Davis McKechnie, Jack Forman, Baylee A. Edwards, Alim Seit-Nebi, Sergei Svarovsky
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-7 (2022)
Lake, Roeder et al. measured neutralizing antibody responses after 2 and 3 doses of mRNA COVID vaccination. Recipients who did not generate strong neutralizing antibody responses after 2 vaccine doses were found to have high levels of neutralizing an
Externí odkaz:
https://doaj.org/article/5dfdb853e5ec457a8c7ccae226e62f7d
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103898- (2022)
Externí odkaz:
https://doaj.org/article/195e307abe2c4cc3b96d943247e49030
Autor:
Alexa J. Roeder, Megan A. Koehler, Paniz Jasbi, Davis McKechnie, John Vanderhoof, Baylee A. Edwards, Maria J. Gonzalez-Moa, Alim Seit-Nebi, Sergei A. Svarovsky, Douglas F. Lake
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1459 (2022)
COVID-19 mRNA vaccines protect against severe disease and hospitalization. Neutralizing antibodies (NAbs) are a first-line defense mechanism, but protective NAb responses are variable. Currently, NAb testing is not widely available. This study employ
Externí odkaz:
https://doaj.org/article/250f3e4aa4a045b59775bab5d2bed4d3
Autor:
Karen V. Kibler, Mateusz Szczerba, Douglas Lake, Alexa J. Roeder, Masmudur Rahman, Brenda G. Hogue, Lok-Yin Roy Wong, Stanley Perlman, Yize Li, Bertram L. Jacobs
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1172 (2022)
The Omicron SARS-CoV-2 variant has been designated as a variant of concern because its spike protein is heavily mutated. In particular, the Omicron spike is mutated at five positions (K417, N440, E484, Q493, and N501) that have been associated with e
Externí odkaz:
https://doaj.org/article/9b8ece6e86844cca8f4922d870287460
Autor:
Alexa J. Roeder, Megan A. Koehler, Sergei Svarovsky, Paniz Jasbi, Alim Seit-Nebi, Maria J. Gonzalez-Moa, John Vanderhoof, Davis McKechnie, Baylee A. Edwards, Douglas F. Lake
BackgroundVaccination with COVID-19 mRNA vaccines prevent hospitalization and severe disease caused by wildtype SARS-CoV-2 and several variants, and likely prevented infection when serum neutralizing antibody (NAb) titers were >1:160. Preventing infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c84e19d32fd1fa64896942d6a2fcb5
https://doi.org/10.1101/2022.03.03.22270812
https://doi.org/10.1101/2022.03.03.22270812
Autor:
Douglas F. Lake, Alexa J. Roeder, Maria J. Gonzalez-Moa, Megan Koehler, Erin Kaleta, Paniz Jasbi, John Vanderhoof, Davis McKechnie, Jack Forman, Baylee A. Edwards, Alim Seit-Nebi, Sergei Svarovsky
Background While evaluating COVID-19 vaccine responses using a rapid neutralizing antibody (NAb) test, we observed that 25% of mRNA vaccine recipients did not neutralize >50%. We termed this group “vaccine poor responders” (VPRs). The objective o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957f2715862ebb9083bccd8280e10e1c
https://doi.org/10.21203/rs.3.rs-1168060/v1
https://doi.org/10.21203/rs.3.rs-1168060/v1
Autor:
Karen V. Kibler, Mateusz Szczerba, Douglas Lake, Alexa J. Roeder, Masmudur Rahman, Brenda G. Hogue, Lok-Yin Roy Wong, Stanley Perlman, Yize Li, Bertram L. Jacobs
The Omicron SARS-CoV-2 variant has been designated a variant of concern because its spike protein is heavily mutated. In particular, Omicron spike is mutated at 5 positions (K417, N440, E484, Q493 and N501) that have been associated with escape from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8baaf671c08c8e46fcac9965442c69b4
https://doi.org/10.1101/2021.12.06.471483
https://doi.org/10.1101/2021.12.06.471483
Autor:
Paniz Jasbi, Megan Koehler, Alim Seit-Nebi, Douglas F. Lake, Alexa J. Roeder, Jack Forman, Sergei A. Svarovsky, Maria J. Gonzalez-Moa, Davis Mckechnie, Baylee Edwards, John Vanderhoof, Erin J. Kaleta
ObjectiveTo determine if poor responders to COVID-19 RNA vaccines (DesignClinical follow-up studySettingAcademic and medical institutions in USAParticipants269 healthy individuals ranging in age from 19 to 80 (Average age = 51; 165 females and 104 ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::087b992d3ec5e0f9349269a880abf88e
https://doi.org/10.1101/2021.11.30.21266716
https://doi.org/10.1101/2021.11.30.21266716
Development of a quantitative antigen assay to detect coccidioidal chitinase-1 (CTS1) in human serum
Autor:
Marie F. Grill, Douglas F. Lake, Francisca J. Grill, Thomas E. Grys, Janis E. Blair, Alexa J. Roeder
Publikováno v:
Open Forum Infectious Diseases
Background Coccidioidomycosis is often diagnosed with a collection of tests that rely on the patient’s ability to mount an immune response to the fungus (antibody-based diagnostics), making diagnosis of this infection challenging. Here we present a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528c6a09609aa3a4ff3e06e5fe6e66c6
https://doi.org/10.1101/2021.05.14.21257226
https://doi.org/10.1101/2021.05.14.21257226
Autor:
John Mills, Alexa J. Roeder, Erin J. Kaleta, Natalia Kuzmina, Maria J. Gonzalez-Moa, Kirsten Pfeffer, Paniz Jasbi, Douglas F. Lake, Kathrine McAulay, Sivakumar Periasamy, Alexander Bukreyev, Sergei A. Svarovsky, Alim Seit-Nebi, Calvin Koelbela, Liang Wu, Thomas E. Grys
Publikováno v:
Journal of Clinical Virology
BackgroundAfter receiving a COVID-19 vaccine, most recipients want to know if they are protected from infection and for how long. Since neutralizing antibodies are a correlate of protection, we developed a lateral flow assay (LFA) that measures level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29755e8e7dc5ce20d2d0e7c4b254138c
http://europepmc.org/articles/PMC8567411
http://europepmc.org/articles/PMC8567411