Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexa Hatcher"'
Autor:
Ryan Higgins, Marie-Helene Kabbaj, Delaney Sherwin, Lauren A. Howell, Alexa Hatcher, Robert J. Tomko, Jr., Yanchang Wang
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107898- (2020)
Summary: The accumulation of misfolded proteins is associated with multiple neurodegenerative disorders, but it remains poorly defined how this accumulation causes cytotoxicity. Here, we demonstrate that the Cdc48/p97 segregase machinery drives the c
Externí odkaz:
https://doaj.org/article/64665d8392944950b3c1f13929211b39
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191490 (2018)
The functionality of a protein depends on its correct folding, but newly synthesized proteins are susceptible to aberrant folding and aggregation. Heat shock proteins (HSPs) function as molecular chaperones that aid in protein folding and the degrada
Externí odkaz:
https://doaj.org/article/eb7c3b585edd40f1a6ca202a0e7f8f4d
Publikováno v:
Handbook on Participatory Action Research and Community Development ISBN: 9781839100970
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381b8225bea8bf18de88d427bf167705
https://doi.org/10.4337/9781839100970.00015
https://doi.org/10.4337/9781839100970.00015
Autor:
Robert J. Tomko, Ryan Higgins, Delaney Sherwin, Yanchang Wang, Alexa Hatcher, Lauren A. Howell, Marie-Helene Miquel Kabbaj
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107898-(2020)
Cell Rep
Cell Rep
Summary: The accumulation of misfolded proteins is associated with multiple neurodegenerative disorders, but it remains poorly defined how this accumulation causes cytotoxicity. Here, we demonstrate that the Cdc48/p97 segregase machinery drives the c