Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alexa Frentzen"'
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 41-61 (2017)
Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model wit
Externí odkaz:
https://doaj.org/article/edcec4d93cc046278ffd6f5ee17b6bd9
Autor:
Marion Adelfinger, Simon Bessler, Alexa Frentzen, Alexander Cecil, Johanna Langbein-Laugwitz, Ivaylo Gentschev, Aladar A. Szalay
Publikováno v:
Viruses, Vol 7, Iss 7, Pp 4075-4092 (2015)
Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a novel approach for canine cancer therapy. Here we describe, for the first time, the characterization and the use of VACV strain GLV-5b451 expressing the anti-vascular endothelia
Externí odkaz:
https://doaj.org/article/88ab6f36bf9548cb804cf9ef3e4dcab8
Autor:
Desislava Tsoneva, Jochen Stritzker, Kristina Bedenk, Qian Zhang, Alexa Frentzen, Joseph Cappello, Utz Fischer, Aladar A Szalay
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137573 (2015)
Blood tests are necessary, easy-to-perform and low-cost alternatives for monitoring of oncolytic virotherapy and other biological therapies in translational research. Here we assessed three candidate proteins with the potential to be used as biomarke
Externí odkaz:
https://doaj.org/article/39eaf199de544a3d95e81dd80153bae9
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
The tumor microenvironment plays an important role in tumor growth and progression. Here we demonstrate that vaccinia virus-mediated, constitutively expressed intratumoral antibodies against vascular endothelial growth factor (VEGF), epidermal growth
Externí odkaz:
https://doaj.org/article/54a8dec159264a21be3de58f971eda3a
Autor:
Marion Adelfinger, Ivaylo Gentschev, Julio Grimm de Guibert, Stephanie Weibel, Johanna Langbein-Laugwitz, Barbara Härtl, Hugo Murua Escobar, Ingo Nolte, Nanhai G Chen, Richard J Aguilar, Yong A Yu, Qian Zhang, Alexa Frentzen, Aladar A Szalay
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104337 (2014)
Virotherapy on the basis of oncolytic vaccinia virus (VACV) infection is a promising approach for cancer therapy. In this study we describe the establishment of a new preclinical model of feline mammary carcinoma (FMC) using a recently established ca
Externí odkaz:
https://doaj.org/article/f26da0749ac54a5c9022bbf85b8606aa
Autor:
Sandeep S Patil, Ivaylo Gentschev, Marion Adelfinger, Ulrike Donat, Michael Hess, Stephanie Weibel, Ingo Nolte, Alexa Frentzen, Aladar A Szalay
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47472 (2012)
Virotherapy using oncolytic vaccinia virus (VACV) strains is one promising new strategy for cancer therapy. We have previously reported that oncolytic vaccinia virus strains expressing an anti-VEGF (Vascular Endothelial Growth Factor) single-chain an
Externí odkaz:
https://doaj.org/article/6c87bf39880f4e64b392fa7fd68a30ea
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 41-61 (2017)
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 41-61 (2017)
Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c0b5ffc28e3517400d4b97fe64a48d
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1317
Herein we describe the use of the vaccinia virus strain GLV-1h68 as a theragnostic agent in cancer models. To date, GLV-1h68 has been used successfully in more than 50 xenograft tumor models. The recombinant vaccinia virus strain has been equipped wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::782114b61c616c94cd2b3897645fa04d
https://pubmed.ncbi.nlm.nih.gov/26072410
https://pubmed.ncbi.nlm.nih.gov/26072410
Publikováno v:
Methods in Molecular Biology ISBN: 9781493927265
Herein we describe the use of the vaccinia virus strain GLV-1h68 as a theragnostic agent in cancer models. To date, GLV-1h68 has been used successfully in more than 50 xenograft tumor models. The recombinant vaccinia virus strain has been equipped wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b717798b26af372ccc23984af5ba02cf
https://doi.org/10.1007/978-1-4939-2727-2_13
https://doi.org/10.1007/978-1-4939-2727-2_13
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss, Pp-(2015)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
The tumor microenvironment plays an important role in tumor growth and progression. Here we demonstrate that vaccinia virus-mediated, constitutively expressed intratumoral antibodies against vascular endothelial growth factor (VEGF), epidermal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4b8728ec8e62acc053e6d6a30baaf
http://www.sciencedirect.com/science/article/pii/S2372770516300067
http://www.sciencedirect.com/science/article/pii/S2372770516300067