Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexa Diiorio"'
Autor:
Ben Umiker, Yasmin Hashambhoy-Ramsay, Jeff Smith, Tanzila Rahman, Amy Mueller, Rachel Davidson, Christina Meyer, Gayatri Patankar, Mohammad Murshid Alam, Sarah Jaffe, Kristin Krukenberg, Allison Goodman, Vikki Spaulding, Michelle Priess, Abha Dhaneshwar, Masie Wong, Alexa Diiorio, Kristin O'Malley, Lara McGrath, Margaret Willer, Lauren Pepper, Monica Gostissa, Katalin Kis-Toth, Dmitri Wiederschain, Heather Cohen, Donald R. Shaffer
Publikováno v:
Molecular Cancer Therapeutics. 22:471-484
Tumor-associated macrophages (TAM) play an important role in maintaining the immunosuppressive state of the tumor microenvironment (TME). High levels of CD163+ TAMs specifically are associated with poor prognosis in many solid tumor types. Targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdc9ed87146b6d569a16703ed901dc0f
https://doi.org/10.1158/1535-7163.mct-22-0351
https://doi.org/10.1158/1535-7163.mct-22-0351
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Sensitivity of LILRB2 as a predictive biomarker for pharmacodynamic response as measured by the macrophage polarization score in histoculture explant cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7300803b6c2959ff55929ff818f38977
https://doi.org/10.1158/1535-7163.22551994.v1
https://doi.org/10.1158/1535-7163.22551994.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Pembrolizumab pharmacodynamic response in histoculture as measured by IFN gamma signature score
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c74996ad1fba63a3aa3c631a0fb2347
https://doi.org/10.1158/1535-7163.22552018
https://doi.org/10.1158/1535-7163.22552018
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Example gating strategy in vitro differentiated M-CSF macrophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7e8c031172fd40cfd9356797944b94
https://doi.org/10.1158/1535-7163.22552009.v1
https://doi.org/10.1158/1535-7163.22552009.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Example gating strategy for tumor samples in order to acquire CD163 and LILRB2 + cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82f29bfc6af14aa9ec7f2d743013250
https://doi.org/10.1158/1535-7163.22552015
https://doi.org/10.1158/1535-7163.22552015
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Example gating strategy in vitro differentiated GM-CSF and IL-4 Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97713a64de1cf9f1c190a1e169a26bea
https://doi.org/10.1158/1535-7163.22552006.v1
https://doi.org/10.1158/1535-7163.22552006.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Changes in gene expression by JTX-8064 in both macrophages and dendritic cells 6 days on treatment during differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81939721f1cd08b9a9a94653e436c78
https://doi.org/10.1158/1535-7163.22495258
https://doi.org/10.1158/1535-7163.22495258
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
A Neutrophil activation assay which measures the frequency CD11b high expression by flow on neutrophils isolated from whole blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78588e9ac62b086e9c5b140ba24c0eb8
https://doi.org/10.1158/1535-7163.22495264.v1
https://doi.org/10.1158/1535-7163.22495264.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Tumor samples used in flow cytometry analysis, in this table the tumor type, the pathology, the total events and the number of CD11b+ cells are shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe768ca41813139a5308f4c9559a726
https://doi.org/10.1158/1535-7163.22495285.v1
https://doi.org/10.1158/1535-7163.22495285.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
A set of 23 anti-LILRB2 antibodies were tested for their ability to block HLA-G tetramer binding to LILRB2 and induce TNF alpha in a macrophage activation assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef93c8c358103617e7447aca7abf108
https://doi.org/10.1158/1535-7163.22495261.v1
https://doi.org/10.1158/1535-7163.22495261.v1