Zobrazeno 1 - 10
of 9 595
pro vyhledávání: '"Alexa C."'
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is a genetic disease resulting in progressive muscle weakness, loss of ambulation, and cardiorespiratory complications. Direct estimation of health-related quality of life for patients with DMD is
Externí odkaz:
https://doaj.org/article/dc090ed88a654c9989faa8c6a9321700
Autor:
Heather I. Greenwood, Cristian K. Maldonado Rodas, Rita I. Freimanis, Alexa C. Glencer, Phoebe N. Miller, Rita A. Mukhtar, Case Brabham, Christina Yau, Jennifer M. Rosenbluth, Gillian L. Hirst, Michael J. Campbell, Alexander Borowsky, Nola Hylton, Laura J. Esserman, Amrita Basu
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract New approaches are needed to determine which ductal carcinoma in situ (DCIS) is at high risk for progression to invasive ductal carcinoma (IDC). We retrospectively studied DCIS patients who declined surgery (2002–2019), and received endocr
Externí odkaz:
https://doaj.org/article/1470ee587e164affa1e41c9b96a0b37b
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background To enhance the utility of functional hemodynamic monitoring, the variables systolic slope (dP/dt) and dynamic arterial elastance (Eadyn) are calculated by the Hypotension Prediction Index (HPI) Acumen® Software. This study was de
Externí odkaz:
https://doaj.org/article/f9983968cb8744e29362712a706aa2ec
Autor:
Sandrine Juillard, Annie Karakeussian-Rimbaud, Marie-Hélène Normand, Julie Turgeon, Charlotte Veilleux-Trinh, Alexa C. Robitaille, Joyce Rauch, Andrzej Chruscinski, Nathalie Grandvaux, Éric Boilard, Marie-Josée Hébert, Mélanie Dieudé
Publikováno v:
Journal of Translational Autoimmunity, Vol 9, Iss , Pp 100250- (2024)
According to a central tenet of classical immune theory, a healthy immune system must avoid self-reactive lymphocyte clones but we now know that B cells repertoire exhibit some level of autoreactivity. These autoreactive B cells are thought to rely o
Externí odkaz:
https://doaj.org/article/3f413fb29e1b49bb99f06fa8ba30c686
Autor:
Miranda Crawford, Alexa C. Alexander
Publikováno v:
Frontiers in Sustainable Food Systems, Vol 8 (2024)
Global pesticide use has resulted in widespread environmental degradation, persistent contamination of surface and ground waters, bioaccumulation of these contaminants in food webs, and unintended impacts on non-target species (e.g., fish kills). Mix
Externí odkaz:
https://doaj.org/article/4fe76f19e14f4d08a7f94322d4049a23
Autor:
Damon Asher, Daisy Dai, Alexa C. Klimchak, Lauren E. Sedita, Katherine L. Gooch, Louise Rodino-Klapac
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 474-483 (2023)
Gene therapies have potential to improve outcomes of severe diseases after only a single administration. Novel therapies are continually being developed using knowledge gained from prior successes, a concept known as scientific spillover. Gene therap
Externí odkaz:
https://doaj.org/article/69bf28089f5a4ed6a5b08d33b57c34b7
Autor:
Daniel G. Diniz, Jhonnathan H. P. de Oliveira, Luma C. F. Guerreiro, Gabriel C. de Menezes, Alexa C. L. de Assis, Tainá Q. Duarte, Izabelly B. D. dos Santos, Flávia D. Maciel, Gabrielly L. da S. Soares, Sanderson C. Araújo, Felipe T. de C. Franco, Ediclei L. do Carmo, Rafaela dos A. B. Morais, Camila M. de Lima, Dora Brites, Daniel C. Anthony, José A. P. Diniz, Cristovam W. P. Diniz
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1420 (2024)
Our study investigated the innate immune response to Toxoplasma gondii infection by assessing microglial phenotypic changes and sickness behavior as inflammatory response markers post-ocular tachyzoite instillation. Disease progression in Swiss albin
Externí odkaz:
https://doaj.org/article/f9723f9eb31f4c3f958a61359f49c3de
Autor:
Alexa C. Gordon, Wen-fai Fong, Sunil Simha, Yuxin Dong, Charles D. Kilpatrick, Adam T. Deller, Stuart D. Ryder, Tarraneh Eftekhari, Marcin Glowacki, Lachlan Marnoch, August R. Muller, Anya E. Nugent, Antonella Palmese, J. Xavier Prochaska, Marc Rafelski, Ryan M. Shannon, Nicolas Tejos
Publikováno v:
The Astrophysical Journal Letters, Vol 963, Iss 2, p L34 (2024)
FRB 20220610A is a high-redshift fast radio burst (FRB) that has not been observed to repeat. Here, we present rest-frame UV and optical Hubble Space Telescope observations of the field of FRB 20220610A. The imaging reveals seven extended sources, on
Externí odkaz:
https://doaj.org/article/3a709f0fabe54adb8a8bc336275fb42b
Autor:
Alexa C. Klimchak, Lauren E. Sedita, Louise R. Rodino-Klapac, Jerry R. Mendell, Craig M. McDonald, Katherine L. Gooch, Daniel C. Malone
Publikováno v:
Journal of Market Access & Health Policy, Vol 11, Iss 1 (2023)
ABSTRACTBackground: Delandistrogene moxeparvovec (SRP-9001) is an investigational gene therapy that may delay progression of Duchenne muscular dystrophy (DMD), a severe, rare neuromuscular disease caused by DMD gene mutations. Early cost-effectivenes
Externí odkaz:
https://doaj.org/article/fc618fecb3e6429197793da05d4a6521
Autor:
Ilya S. Khrykin, Metin Ata, Khee-Gan Lee, Sunil Simha, Yuxin Huang, J. Xavier Prochaska, Nicolas Tejos, Keith W. Bannister, Jeff Cooke, Cherie K. Day, Adam Deller, Marcin Glowacki, Alexa C. Gordon, Clancy W. James, Lachlan Marnoch, Ryan. M. Shannon, Jielai Zhang, Lucas Bernales-Cortes
Publikováno v:
The Astrophysical Journal, Vol 973, Iss 2, p 151 (2024)
The dispersion measure of fast radio bursts (FRBs), arising from the interactions with free electrons along the propagation path, constitutes a unique probe of the cosmic baryon distribution. Their constraining power is further enhanced in combinatio
Externí odkaz:
https://doaj.org/article/6f8966a67c6b42b59b25481872b79dca