Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexa, Torelli"'
Publikováno v:
Angewandte Chemie. 133:20393-20398
An enantioselective consecutive cyclization/coupling process, catalyzed by palladium is reported. Stereoinduction arises from an enantioselective carbopalladation, generating an intermediate which promotes a nucleopalladation step. The dual cyclizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5e36a9120d03d6918a1cb213167472
https://doi.org/10.1002/ange.202106518
https://doi.org/10.1002/ange.202106518
Publikováno v:
ACS Catalysis. 10:11578-11622
Organoboronates represent a cornerstone functional group in modern synthesis owing to their unique reactivity and divergent synthetic capability. Copper catalysis has become one of the most powerfu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b92776ab2abdd9a54248441ec5b009
https://doi.org/10.1021/acscatal.0c02758
https://doi.org/10.1021/acscatal.0c02758
Publikováno v:
Journal of the American Chemical Society. 142:9510-9517
An asymmetric hydroarylative cyclization of enynes involving a C-H bond cleavage is reported. The cobalt-catalyzed cascade generates three new bonds in an atom-economical fashion. The products were obtained in excellent yields and excellent enantiose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc0864a9097761a1cda9161873f9a3c
https://doi.org/10.1021/jacs.0c03246
https://doi.org/10.1021/jacs.0c03246
Autor:
Mark Lautens, Nicolas Zeidan, Alexa Torelli, Bijan Mirabi, Matthew Zambri, Sven Unger, Christian Dank
Publikováno v:
Organic Letters
A dearomative electrophilic fluorination of 2-methylindoles is reported, delivering 3,3-difluoroindolines bearing an exomethylidene. The model substrate was synthesized on up to a 20 mmol scale and was purified by a practical recrystallization as a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3551aa92fc63ef9036d80affa85a8870
https://doi.org/10.1021/acs.orglett.0c01175
https://doi.org/10.1021/acs.orglett.0c01175
Publikováno v:
ACS Catalysis. 9:9253-9258
A diastereo- and enantioselective synthesis of boron-containing cyclobutanols is reported. We exploit an enantioselective borylcupration to generate a chiral benzylic copper intermediate that is in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0896955167a7190b17d080a03adccd03
https://doi.org/10.1021/acscatal.9b03216
https://doi.org/10.1021/acscatal.9b03216
Publikováno v:
Angewandte Chemie (International ed. in English). 60(37)
An enantioselective consecutive cyclization/coupling process, catalyzed by palladium is reported. Stereoinduction arises from an enantioselective carbopalladation, generating an intermediate which promotes a nucleopalladation step. The dual cyclizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b74fa9fbbe4aae8b8a8766824254e3fd
https://pubmed.ncbi.nlm.nih.gov/34240542
https://pubmed.ncbi.nlm.nih.gov/34240542
Publikováno v:
Organic letters. 23(7)
The utilization of the Bpin group as a pronucleophile to facilitate the assembly of cyclic carbamates has been achieved. This one-pot process involves an initial copper-catalyzed borylation, a subsequent C-B bond oxidation to generate the reactive al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e8eb1c0ff3ff997d3e0f35507bd6a8
https://pubmed.ncbi.nlm.nih.gov/33689389
https://pubmed.ncbi.nlm.nih.gov/33689389
Publikováno v:
Angewandte Chemie.
We report a cobalt-catalyzed hydroacylation of 1,6-enynes with exogenous aldehydes in a domino sequence to construct enantioenriched ketones. The products were obtained in good yields with excellent regio-, diastereo-, and enantioselectivity. Further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4579d15f0ce4ae332cf726e2159d4367
https://doi.org/10.1002/ange.202006716
https://doi.org/10.1002/ange.202006716
Autor:
Alexa Torelli, Mark Lautens
Publikováno v:
Synfacts. 17:1232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef15808771cf09b7017d87d9bcb83fde
https://doi.org/10.1055/s-0040-1720671
https://doi.org/10.1055/s-0040-1720671
Autor:
Alexa Torelli, Mark Lautens
Publikováno v:
Synfacts. 17:1233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c54f457b8503481653b493c13822f6
https://doi.org/10.1055/s-0040-1720669
https://doi.org/10.1055/s-0040-1720669