Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Alex de Mendoza"'
Autor:
Ya Gao, Daisylyn Senna Tan, Mathias Girbig, Haoqing Hu, Xiaomin Zhou, Qianwen Xie, Shi Wing Yeung, Kin Shing Lee, Sik Yin Ho, Vlad Cojocaru, Jian Yan, Georg K. A. Hochberg, Alex de Mendoza, Ralf Jauch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stem cells are a hallmark of animal multicellularity. Sox and POU transcription factors are associated with stemness and were believed to be animal innovations, reported absent in their unicellular relatives. Here we describe unicellular Sox
Externí odkaz:
https://doaj.org/article/49ecad2e0c904009b9fb295d79784ea9
Autor:
Kero Guynes, Luke A. Sarre, Allan M. Carrillo-Baltodano, Billie E. Davies, Lan Xu, Yan Liang, Francisco M. Martín-Zamora, Paul J. Hurd, Alex de Mendoza, José M. Martín-Durán
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background DNA methylation in the form of 5-methylcytosine (5mC) is the most abundant base modification in animals. However, 5mC levels vary widely across taxa. While vertebrate genomes are hypermethylated, in most invertebrates, 5mC concent
Externí odkaz:
https://doaj.org/article/20a431888cef488aa839a5075a92be08
Autor:
Leonie Dossmann, Max Emperle, Michael Dukatz, Alex de Mendoza, Pavel Bashtrykov, Albert Jeltsch
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The DNA methyltransferase DNMT3C appeared as a duplication of the DNMT3B gene in muroids and is required for silencing of young retrotransposons in the male germline. Using specialized assay systems, we investigate the flanking sequence pref
Externí odkaz:
https://doaj.org/article/926964ba06e8461bbcb0aa1dd8e6a35e
Autor:
Alex de Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Sam Buckberry, Jahnvi Pflueger, Matthew R. Grimmer, Sabine Stolzenburg, Ozren Bogdanovic, Alicia Oshlack, Peggy J. Farnham, Pilar Blancafort, Ryan Lister
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome engineering techniques enable direct testing of the effect of induced DNA methylation on endogenou
Externí odkaz:
https://doaj.org/article/b7e0ceb7c87f42b496fd72cdb8d5a2de
Autor:
Nathan J. Kenny, Warren R. Francis, Ramón E. Rivera-Vicéns, Ksenia Juravel, Alex de Mendoza, Cristina Díez-Vives, Ryan Lister, Luis A. Bezares-Calderón, Lauren Grombacher, Maša Roller, Lael D. Barlow, Sara Camilli, Joseph F. Ryan, Gert Wörheide, April L. Hill, Ana Riesgo, Sally P. Leys
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Reconstructing the early molecular evolution of animals requires genomic resources for non-bilaterian animals. Here, the authors present the chromosome-level genome of a freshwater sponge together with analyses of its genome architecture, methylation
Externí odkaz:
https://doaj.org/article/8d419b3de9c44cb5aff1f089896aba4c
Autor:
Isabel Almudi, Joel Vizueta, Christopher D. R. Wyatt, Alex de Mendoza, Ferdinand Marlétaz, Panos N. Firbas, Roberto Feuda, Giulio Masiero, Patricia Medina, Ana Alcaina-Caro, Fernando Cruz, Jessica Gómez-Garrido, Marta Gut, Tyler S. Alioto, Carlos Vargas-Chavez, Kristofer Davie, Bernhard Misof, Josefa González, Stein Aerts, Ryan Lister, Jordi Paps, Julio Rozas, Alejandro Sánchez-Gracia, Manuel Irimia, Ignacio Maeso, Fernando Casares
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Genomic studies of paleopteran insects, such as mayflies, are needed to reconstruct early insect evolution. Here, Almudi and colleagues present the genome of the mayfly Cloeon dipterum and use transcriptomics to characterize its adaptations to distin
Externí odkaz:
https://doaj.org/article/c1ed19c7d3394dea8a552561ecaa07b7
Autor:
Alex de Mendoza, Amandine Bonnet, Dulce B. Vargas-Landin, Nanjing Ji, Hongfei Li, Feng Yang, Ling Li, Koichi Hori, Jahnvi Pflueger, Sam Buckberry, Hiroyuki Ohta, Nedeljka Rosic, Pascale Lesage, Senjie Lin, Ryan Lister
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Cytosine methyltransferases (DNMTs) often silence transposons in eukaryotic genomes. Here the authors describe the recurrent acquisition of DNMTs by transposons from two distantly-related eukaryotes and suggest that methylation of CG dinucleotides by
Externí odkaz:
https://doaj.org/article/3297be576e064a6fa4a2ceb931910d37
Autor:
Alex de Mendoza, Amandine Bonnet, Dulce B. Vargas-Landin, Nanjing Ji, Hongfei Li, Feng Yang, Ling Li, Koichi Hori, Jahnvi Pflueger, Sam Buckberry, Hiroyuki Ohta, Nedeljka Rosic, Pascale Lesage, Senjie Lin, Ryan Lister
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Hongfei Li, which was incorrectly given as Fei Hong. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3a722731f3ed42feba32bfacd97d6c88
Publikováno v:
eLife, Vol 4 (2015)
Cell-type specification through differential genome regulation is a hallmark of complex multicellularity. However, it remains unclear how this process evolved during the transition from unicellular to multicellular organisms. To address this question
Externí odkaz:
https://doaj.org/article/f72615d029664681837ea62a0e23d8a5
Autor:
Alex de Mendoza, Iñaki Ruiz-Trillo
Publikováno v:
eLife, Vol 3 (2014)
A genetic screen has revealed one of the molecules that allow choanoflagellates, the closest unicellular relative of animals, to form colonies, which could help researchers to answer questions about the earliest days of animal evolution.
Externí odkaz:
https://doaj.org/article/6431e801df66405d89dd047bc10e192a