Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alex Zizzo"'
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
To date, few FDA-approved medical countermeasures are available for addressing hematopoietic acute radiation syndrome (H-ARS). In this study, we present our latest research findings focusing on the evaluation of a novel radiation mitigator known as t
Externí odkaz:
https://doaj.org/article/e99022922d0d454cabb77f2ba0923e28
Publikováno v:
Animal Microbiome, Vol 5, Iss 1, Pp 1-13 (2023)
Abstract Background Recent studies have shown that gut microbiome plays important roles in response to radiation exposure. IL-18, an inflammatory cytokine, is highly elevated in mice, mini-pigs and nonhuman primates after radiation exposure. Blocking
Externí odkaz:
https://doaj.org/article/16232d5c931a48c0a7c626f5dcbb4a8b
Publikováno v:
Toxics, Vol 12, Iss 1, p 5 (2023)
IL-18 has been shown to play important roles in response to total body irradiation. However, homogenous total body irradiation is not a realistic model to reflect the radiation exposure in a real nuclear event. To further study the roles of IL-18 in
Externí odkaz:
https://doaj.org/article/6f5c0c31749c44c1a581b98a874e1da0
Autor:
Mang Xiao, Xianghong Li, Li Wang, Bin Lin, Min Zhai, Lisa Hull, Alex Zizzo, Wanchang Cui, Juliann G. Kiang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10701 (2023)
Radiation injury- and radiation combined with skin injury-induced inflammatory responses in the mouse brain were evaluated in this study. Female B6D2F1/J mice were subjected to a sham, a skin wound (SW), 9.5 Gy 60Co total-body gamma irradiation (RI),
Externí odkaz:
https://doaj.org/article/ee38a05dd27443b98a1d0fb987b6ec6b
Autor:
Li Wang, Bin Lin, Min Zhai, Wanchang Cui, Lisa Hull, Alex Zizzo, Xianghong Li, Juliann G. Kiang, Mang Xiao
Publikováno v:
Toxics, Vol 10, Iss 12, p 785 (2022)
Radiation-combined injury (RCI) augments the risk of morbidity and mortality when compared to radiation injury (RI) alone. No FDA-approved medical countermeasures (MCMs) are available for treating RCI. Previous studies implied that RI and RCI elicit
Externí odkaz:
https://doaj.org/article/f2176aeda7ac4e22beee88d7e0c63024
Publikováno v:
Toxics, Vol 11, Iss 1, p 35 (2022)
Administration of recombinant human IL-18 binding protein (rhIL-18BP), a natural antagonist of IL-18, significantly increased mouse survival after lethal doses of irradiation. To further understand the roles of IL-18BP in radiation mitigation, we stu
Externí odkaz:
https://doaj.org/article/2a93094498094adfabcb8901b90e620b
Autor:
Kiang, Mang Xiao, Xianghong Li, Li Wang, Bin Lin, Min Zhai, Lisa Hull, Alex Zizzo, Wanchang Cui, Juliann G.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10701
Radiation injury- and radiation combined with skin injury-induced inflammatory responses in the mouse brain were evaluated in this study. Female B6D2F1/J mice were subjected to a sham, a skin wound (SW), 9.5 Gy 60Co total-body gamma irradiation (RI),