Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alex Wamachi"'
Autor:
Indu Malhotra, Arlene Dent, Peter Mungai, Alex Wamachi, John H Ouma, David L Narum, Eric Muchiri, Daniel J Tisch, Christopher L King
Publikováno v:
PLoS Medicine, Vol 6, Iss 7, p e1000116 (2009)
Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or their soluble products, thereby stimulating T and B cell immune responses to malaria blood stage antigens. We hypothesized that fetal immune priming, or malaria exposure in
Externí odkaz:
https://doaj.org/article/b8b043e120ef4c3487f2705b87086d64
Autor:
Ann M. Moormann, Indu Malhotra, Christopher L. King, Davy K. Koech, Eric M. Muchiri, Elton Mzungu, Peter Mungai, Alex Wamachi
Publikováno v:
The Journal of Immunology. 180:3383-3390
Cord blood T cells have been reported to respond to a variety of exogenous Ags, including environmental allergens and various viruses and parasites, as demonstrated by enhanced proliferation and cytokine secretion. This finding is evidence that Ags i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9586cdac116c2b804b8483163d64a1e
https://doi.org/10.4049/jimmunol.180.5.3383
https://doi.org/10.4049/jimmunol.180.5.3383
Autor:
Indu Malhotra, John H. Ouma, Christopher L. King, Maureen Gallagher, Peter Mungai, Eric M. Muchiri, Alex Wamachi, John Kioko
Publikováno v:
AIDS. 19:1849-1855
Objective: To investigate the effect of helminth and/or malaria infection on the risk of HIV infection in pregnant women and its transmission to their offspring. Design: A retrospective cohort study of pregnant Kenyan women and their offspring from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ae9e8712469dfb528fcbce06fdb41e
https://doi.org/10.1097/01.aids.0000189846.90946.5d
https://doi.org/10.1097/01.aids.0000189846.90946.5d
Autor:
Japhet Magambo, Peter Mungai, Phillip L. Magak, John H. Ouma, Davy K. Koech, Eric M. Muchiri, Christopher L. King, Charles H. King, Jyoti S. Mayadev, Alex Wamachi
Publikováno v:
The Journal of Infectious Diseases. 190:2020-2030
Bladder and kidney disease, which affect approximately 25%-30% of subjects infected with Schistosoma haematobium, are mediated by T cell-dependent granulomatous responses to schistosome eggs. To determine why only some infected subjects develop disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965eea2de9cd21a5e3a469ba9ef3f4c4
https://doi.org/10.1086/425579
https://doi.org/10.1086/425579
Autor:
Indu Malhotra, John Kioko, John H. Ouma, Peter Mungai, Alex Wamachi, Christopher L. King, Eric M. Muchiri
Publikováno v:
The Journal of Infectious Diseases. 184:1176-1182
This study examined the hypothesis that the nature of the host cellular immune response to schistosome ova is a risk factor for urinary tract morbidity in areas in which Schistosoma haematobium is endemic. S. haematobium-infected children and adolesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996602334c277e0afc484eb1d09138bf
https://doi.org/10.1086/323802
https://doi.org/10.1086/323802
Autor:
Peter A. Zimmerman, Aaron A.R. Tobian, Rajeev K. Mehlotra, Indu Malhotra, Davy K. Koech, John H. Ouma, Christopher L. King, Alex Wamachi, Peter Mungai
Publikováno v:
The Journal of Infectious Diseases. 182:558-563
Summary of all single-, double-, and triple-species infections detected bypolymerase chain reaction. Parasite combinationNo. of mothers infected ( n p102)No. of newborns (cord blood)infected ( n p 102)Observed Expected x 2 (1 df ) Observed Expected x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a64cad353f075c3e9050c916f089e6
https://doi.org/10.1086/315729
https://doi.org/10.1086/315729
Autor:
Indu Malhotra, Peter Mungai, Alex Wamachi, John Kioko, John H. Ouma, James W. Kazura, Christopher L. King
Publikováno v:
The Journal of Immunology. 162:6843-6848
Infants and children are routinely vaccinated with bacillus Calmette-Guérin (BCG) in areas of the world where worm infections are common. Because maternal helminth infection during pregnancy can sensitize the developing fetus, we studied whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c504e223d2d4a35eb49564a9e77c58a
https://doi.org/10.4049/jimmunol.162.11.6843
https://doi.org/10.4049/jimmunol.162.11.6843
Autor:
Christopher L. King, Indu Malhotra, Peter Mungai, Alex Wamachi, John Kioko, John H. Ouma, James W. Kazura
Publikováno v:
The Journal of Immunology. 160:3578-3584
Human neonates are generally deficient in their ability to generate humoral immunity. This deficiency is thought to reflect physiologic immaturity of T and B cell function and lack of previous exposure to exogenous Ags. To determine whether neonatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a658cc6d08bce61da4d9fa1a67227f5
https://doi.org/10.4049/jimmunol.160.7.3578
https://doi.org/10.4049/jimmunol.160.7.3578
Autor:
Adams Omollo, Davy K. Koech, John H. Ouma, John Kioko, James W. Kazura, Lynne Elson, Indu Malhotra, Christopher L. King, Alex Wamachi, Peter Mungai
Publikováno v:
Journal of Clinical Investigation. 99:1759-1766
Neonates exposed to parasite antigens (Ags) in utero may develop altered fetal immunity that could affect subsequent responses to infection. We hypothesized that cord blood lymphocytes (CBL) from offspring of mothers residing in an area highly endemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595cce2e61389209e4ccb4adf4c1f0d5
https://doi.org/10.1172/jci119340
https://doi.org/10.1172/jci119340
Autor:
Arlene E. Dent, John H. Ouma, Indu Malhotra, Alex Wamachi, David L. Narum, Peter Mungai, Daniel J. Tisch, Eric M. Muchiri, Christopher L. King
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 6, Iss 7, p e1000116 (2009)
PLoS Medicine, Vol 6, Iss 7, p e1000116 (2009)
Background Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or their soluble products, thereby stimulating T and B cell immune responses to malaria blood stage antigens. We hypothesized that fetal immune priming, or malaria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf211b0971ecff07273ddae23c09f9c
https://pubmed.ncbi.nlm.nih.gov/19636354
https://pubmed.ncbi.nlm.nih.gov/19636354