Výsledky vyhledávání - "Alex W. Chen"

Protein Geometry and Placement in the Cardiac Dyad Influence Macroscopic Properties of Calcium-Induced Calcium Release

Autor: Raimond L. Winslow, Alex W. Chen, Antti J. Tanskanen, Joseph L. Greenstein, Sean X. Sun

Publikováno v: Biophysical Journal. 92(10):3379-3396

In cardiac ventricular myocytes, events crucial to excitation-contraction coupling take place in spatially restricted microdomains known as dyads. The movement and dynamics of calcium (Ca2+) ions in the dyad have often been described by assigning con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c53f4d27913adeeee76cde3f1505569

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Functional Consequences of Directed Mutations in Human Papillomavirus E6 Proteins: Abrogation of p53-Mediated Cell Cycle Arrest Correlates with p53 Binding and Degradation in Vitro

Autor: Lora Hedrick, Theodore D. Kessis, Sung M. Han, Kathleen R. Cho, Alex W. Chen, Robbert J. C. Slebos

Publikováno v: Virology. 208:111-120

Clinical and epidemiological studies have implicated the involvement of human papillomavirus (HPV) infection in cervical tumorigenesis. We have previously shown that expression of high-risk (HPV16) E6 can abrogate an important cell cycle checkpoint m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60450a920d10cdf3a1affff18833ba3
https://doi.org/10.1006/viro.1995.1134

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