Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Alex Vo"'
Autor:
Md Fashiar Rahman, Tzu-Liang (Bill) Tseng, Michael Pokojovy, Peter McCaffrey, Eric Walser, Scott Moen, Alex Vo, Johnny C. Ho
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1699 (2024)
The class activation map (CAM) represents the neural-network-derived region of interest, which can help clarify the mechanism of the convolutional neural network’s determination of any class of interest. In medical imaging, it can help medical prac
Externí odkaz:
https://doaj.org/article/478dda27636042f9a84eb847defb046d
Autor:
Kenneth Gilbert, Raphael Joseph, Alex Vo, Trusha Patel, Samiya Chaudhry, Uyen Nguyen, Amy Trevor, Erica Robinson, Margaret Campbell, John McLennan, Farielle Houran, Tristan Wong, Kendra Flann, Melissa Wages, Elizabeth A. Palmer, John Peterson, John Engle, Tom Maier, Curtis A. Machida
Publikováno v:
Journal of Oral Microbiology, Vol 6, Iss 0, Pp 1-11 (2014)
Background and objectives: Mutans streptococci (MS) are one of the major microbiological determinants of dental caries. The objectives of this study are to identify distinct MS and non-MS streptococci strains that are located at carious sites and non
Externí odkaz:
https://doaj.org/article/658ef73e38c24a338f54d2b723b36251
Autor:
Elizabeth A. Palmer, Alex Vo, Shelby B. Hiles, Patricia Peirano, Samyia Chaudhry, Amy Trevor, Iraj Kasimi, Jill Pollard, Christopher Kyles, Michael Leo, Beth Wilmot, John Engle, John Peterson, Tom Maier, Curtis A. Machida
Publikováno v:
Journal of Oral Microbiology, Vol 4, Iss 0, Pp 1-11 (2012)
Background: Genotypic strains of cariogenic mutans streptococci (MS) may vary in important virulence properties. In previous published studies, we identified 39 MS strains from pediatric patients undergoing full-mouth dental rehabilitation, including
Externí odkaz:
https://doaj.org/article/a011740cb07541908f39c20da8b3723b
Autor:
Agata N. Makar, Alina Boraman, Peter Mosen, Joanne E. Simpson, Jair Marques, Tim Michelberger, Stuart Aitken, Ann P. Wheeler, Dominic Winter, Alex von Kriegsheim, Noor Gammoh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen,
Externí odkaz:
https://doaj.org/article/6883251db50c4cf790616ebe8bd9529f
Autor:
Giovana Carrasco, Ifigeneia Stavrou, Mairi Treanor-Taylor, Henry Beetham, Martin Lee, Roza Masalmeh, Artur Carreras-Soldevila, David Hardman, Miguel O. Bernabeu, Alex von Kriegsheim, Gareth J. Inman, Adam Byron, Valerie G. Brunton
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-12 (2024)
Abstract Kindler syndrome (KS) is a rare genodermatosis resulting from loss-of-function mutations in FERMT1, the gene that encodes Kindlin-1. KS patients have a high propensity to develop aggressive and metastatic cutaneous squamous cell carcinoma (c
Externí odkaz:
https://doaj.org/article/8cc9d5b92cf442b7a04bdf1f0c5b321a
Autor:
Laura Téblick, Marijana Lipovac, Margo Bell, Annemie De Smet, Ingrid De Meester, Peter Delputte, Alex Vorsters
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract First-void urine (FVU) samples, containing human papillomavirus (HPV)-specific IgG from female genital tract secretions, provide a non-invasive option for disease monitoring and vaccine impact assessment. This study explores the utility of F
Externí odkaz:
https://doaj.org/article/3eed7e019866404eb77f8ff00d2395a0
Autor:
Hao Sun, Kristen A. Cardinal, Larry Wienkers, Alice Chin, Vineet Kumar, Calvin Neace, Clark Henderson, Christopher J. Endres, Ariel Topletz-Erickson, Kelly Regal, Alex Vo, Stephen C. Alley, Anthony J. Lee
Publikováno v:
Cancer chemotherapy and pharmacology. 89(6)
Tucatinib, a small molecule for the treatment of metastatic HER2-positive breast cancer, was extensively metabolized in humans to multiple oxidative metabolites. To fully understand the elimination and biotransformation pathways of tucatinib, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ec46a252316d2348fe244993f0977
https://pubmed.ncbi.nlm.nih.gov/35435471
https://pubmed.ncbi.nlm.nih.gov/35435471
Autor:
Roly Megaw, Abigail Moye, Zhixian Zhang, Fay Newton, Fraser McPhie, Laura C. Murphy, Lisa McKie, Feng He, Melissa K. Jungnickel, Alex von Kriegsheim, Peter A. Tennant, Chloe Brotherton, Christine Gurniak, Alecia K. Gross, Laura M. Machesky, Theodore G. Wensel, Pleasantine Mill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract As signalling organelles, cilia regulate their G protein-coupled receptor content by ectocytosis, a process requiring localised actin dynamics to alter membrane shape. Photoreceptor outer segments comprise an expanse of folded membranes (dis
Externí odkaz:
https://doaj.org/article/162f25833a9b438992ccafbff79b3556
Autor:
Laura Téblick, Marijana Lipovac, Freya Molenberghs, Peter Delputte, Winnok H. De Vos, Alex Vorsters
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTHuman papillomavirus (HPV) vaccines, primarily relying on neutralizing antibodies, have proven highly effective. Recently, HPV-specific antibodies have been detected in the female genital tract secretions captured by first-void urine (FVU), o
Externí odkaz:
https://doaj.org/article/6124eafab9954e1093d1587a1d45969f
Autor:
Vita W. Jongen, Ceranza Daans, Ard van Sighem, Maarten Schim van der Loeff, Kris Hage, Camiel Welling, Alex von Vaupel‐Klein, Martin den Heijer, Edgar J. G. Peters, Marc van der Valk, Peter Reiss, Maria Prins, Elske Hoornenborg, the ATHENA observational HIV cohort
Publikováno v:
Journal of the International AIDS Society, Vol 27, Iss 8, Pp n/a-n/a (2024)
Abstract Introduction Transgender women are at increased risk of acquiring HIV. Earlier studies reported lower retention in HIV care, antiretroviral therapy uptake, adherence and viral suppression. We assessed the stages of the HIV care continuum of
Externí odkaz:
https://doaj.org/article/997d688cef1b47b78eaef88a11a95747