Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alex Vira"'
Autor:
Branca I. Pereira, Oliver P. Devine, Milica Vukmanovic-Stejic, Emma S. Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J. Sebire, Veronica Kinsler, Alexis Valdovinos, Claude Jourdan LeSaux, João F. Passos, Antony Antoniou, Malcom H. A. Rustin, Judith Campisi, Arne N. Akbar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Senescent cells increase with ageing and may cause inflammatory conditions, but how this accumulation is mediated is still unclear. Here the authors show that senescent cells express HLA-E to suppress NKG2A-mediated natural killer and CD8 T cell acti
Externí odkaz:
https://doaj.org/article/a849def66981451db25ae5092d6b7804
Autor:
Luca Urbani, Carlotta Camilli, Demetra-Ellie Phylactopoulos, Claire Crowley, Dipa Natarajan, Federico Scottoni, Panayiotis Maghsoudlou, Conor J. McCann, Alessandro Filippo Pellegata, Anna Urciuolo, Koichi Deguchi, Sahira Khalaf, Salvatore Ferdinando Aruta, Maria Cristina Signorelli, David Kiely, Edward Hannon, Matteo Trevisan, Rui Rachel Wong, Marc Olivier Baradez, Dale Moulding, Alex Virasami, Asllan Gjinovci, Stavros Loukogeorgakis, Sara Mantero, Nikhil Thapar, Neil Sebire, Simon Eaton, Mark Lowdell, Giulio Cossu, Paola Bonfanti, Paolo De Coppi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Combining decellularised scaffolds with patient-derived cells holds promise for bioengineering of functional tissues. Here the authors develop a two-stage approach to engineer an oesophageal graft that retains the structural organisation of native oe
Externí odkaz:
https://doaj.org/article/04035db7e1a6472b9d4fc0a2bd25b51a
Autor:
Julien Baruteau, Dany P. Perocheau, Joanna Hanley, Maëlle Lorvellec, Eridan Rocha-Ferreira, Rajvinder Karda, Joanne Ng, Natalie Suff, Juan Antinao Diaz, Ahad A. Rahim, Michael P. Hughes, Blerida Banushi, Helen Prunty, Mariya Hristova, Deborah A. Ridout, Alex Virasami, Simon Heales, Stewen J. Howe, Suzanne M. K. Buckley, Philippa B. Mills, Paul Gissen, Simon N. Waddington
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Patients with mutations in the ASL gene present with argininosuccinic aciduria characterised by hyperammonaemia and cognitive impairment. Here, the authors show that cerebral disease involves neuronal nitrosative/oxidative stress that is not induced
Externí odkaz:
https://doaj.org/article/bccd48b998f7466b8b4e37f6409acdb2
Autor:
Jose Mario Gonzalez-Meljem, Scott Haston, Gabriela Carreno, John R. Apps, Sara Pozzi, Christina Stache, Grace Kaushal, Alex Virasami, Leonidas Panousopoulos, Seyedeh Neda Mousavy-Gharavy, Ana Guerrero, Mamunur Rashid, Nital Jani, Colin R. Goding, Thomas S. Jacques, David J. Adams, Jesus Gil, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Senescent cells can promote tumour progression through the activation of a senescenceassociated secretory phenotype (SASP). Here, the authors show that SASP activation is associated with non-cell autonomous cell transformation and tumour initiation i
Externí odkaz:
https://doaj.org/article/a0474958863a4634a3e1c6faf8951dc5
Autor:
John R. Apps, J. Ciaran Hutchinson, Susan Shelmerdine, Alex Virasami, Eduard Winter, Thomas S. Jacques, Juan-Pedro Martinez-Barbera, Owen Arthurs, Thomas Czech
Publikováno v:
F1000Research, Vol 8 (2019)
This manuscript describes the study of two cases of craniopharyngioma, which have been examined repeatedly over three separate centuries. This includes analysis by Josef Engel in 1839, who sought to uncover the physiological role of the pituitary gla
Externí odkaz:
https://doaj.org/article/e1f70f2e62ee42b18c173a2382433568
Publikováno v:
Environmental Science & Technology. 23:403-406