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pro vyhledávání: '"Alex Veith"'
Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome
Autor:
Krithika Lingappan, Suman Maity, Weiwu Jiang, Lihua Wang, Xanthi Couroucli, Alex Veith, Guodong Zhou, Cristian Coarfa, Bhagavatula Moorthy
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Hyperoxia contributes to lung injury in experimental animals and diseases such as acute respiratory distress syndrome in humans. Cytochrome P450 (CYP)1A enzymes are protective against hyperoxic lung injury (HLI). The molecular pathways and d
Externí odkaz:
https://doaj.org/article/be3f02f52efc4a6089bd1e5a396ef06d
Autor:
Xanthi I. Couroucli, Boura'a Bou Aram, Lihua Wang, Weiwu Jiang, Alex Veith, Krithika Lingappan, Guodong Zhou, Colin R. Jefcoate, Bhagavatula Moorthy
Publikováno v:
Toxicological Sciences. 165:462-474
Supplemental oxygen is a life-saving intervention administered to individuals suffering from respiratory distress, including adults with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Despite the clinical benefit, supplementa
Analysis of Hyperoxic Lung Injury in Mice Deficient in Gene for Cytochrome P450 (CYP)1b1, 1a1 or 1a2
Publikováno v:
D32. ACUTE LUNG INJURY AND ARDS: CLINICAL AND MECHANISTIC STUDIES.
Publikováno v:
The FASEB Journal. 33
Publikováno v:
The FASEB Journal. 32
Autor:
Alex Veith, Bhagavatula Moorthy
Publikováno v:
Current opinion in toxicology. 7
The cytochrome P450 (CYP) enzymes are a diverse group of heme monooxygenases that, through the course of their reaction cycle, contribute to cellular reactive oxygen species (ROS). CYP enzymes play a crucial role in human physiology and are involved
Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome
Autor:
Xanthi I. Couroucli, Alex Veith, Weiwu Jiang, Cristian Coarfa, Bhagavatula Moorthy, Suman Maity, Krithika Lingappan, Lihua Wang, Guodong Zhou
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Hyperoxia contributes to lung injury in experimental animals and diseases such as acute respiratory distress syndrome in humans. Cytochrome P450 (CYP)1A enzymes are protective against hyperoxic lung injury (HLI). The molecular pathways and difference
Publikováno v:
Journal of Biological Chemistry. 289:3703-3712
Insufficient expression of the survival motor neuron (SMN) protein causes spinal muscular atrophy, a neurodegenerative disease characterized by loss of motor neurons. Despite the importance of maintaining adequate SMN levels, little is known about fa
Autor:
Xanthi I. Couroucli, Daniela Dinu, Chun Chu, Colin R. Jefcoate, Alex Veith, Krithika Lingappan, Bhagavatula Moorthy, Nader Sheibani
Supplemental oxygen, which is routinely administered to preterm infants with pulmonary insufficiency, contributes to bronchopulmonary dysplasia (BPD) in these infants. Hyperoxia also contributes to the development of acute lung injury (ALI) and acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53f1301bc5dad286ceea3e5457a2c37
https://europepmc.org/articles/PMC4935552/
https://europepmc.org/articles/PMC4935552/
Autor:
Christophe Verbeurgt, Alex Veithen, Sébastien Carlot, Maxime Tarabichi, Jacques E Dumont, Sergio Hassid, Pierre Chatelain
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0181302 (2017)
T2R38 has been shown to be a specific bacterial detector implicated in innate immune defense mechanism of human upper airway. Several clinical studies have demonstrated that this receptor is associated with the development of chronic rhinosinusitis (
Externí odkaz:
https://doaj.org/article/ed08c05c466b4d7781f3b0b8940f609d