Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alex Siu-Wing Chan"'
Autor:
Jane Siu-Fan Li, Philip Chiu-Tsun Tang, Chun Kit K. Choi, Alex Siu-Wing Chan, Calvin Sze-Hang Ng, Ka-Fai To, Patrick Ming-Kuen Tang
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102823- (2024)
Summary: Immunodynamics in the tumor microenvironment can be precisely examined by using multiple antigen identification approaches. Here, we present a protocol for capturing expression levels of multiple target proteins in the same specimen at singl
Externí odkaz:
https://doaj.org/article/cd4afc4f3ab7487fb859f4714d8f1397
Autor:
Philip Chiu‐Tsun Tang, Max Kam‐Kwan Chan, Jeff Yat‐Fai Chung, Alex Siu‐Wing Chan, Dongmei Zhang, Chunjie Li, Kam‐Tong Leung, Calvin Sze‐Hang Ng, Yi Wu, Ka‐Fai To, Hui‐Yao Lan, Patrick Ming‐Kuen Tang
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract Macrophage‐myofibroblast transition (MMT) is a newly discovered pathway for mass production of pro‐tumoral cancer‐associated fibroblasts (CAFs) in non‐small cell lung carcinoma (NSCLC) in a TGF‐β1/Smad3 dependent manner. Better un
Externí odkaz:
https://doaj.org/article/87ee915054aa49ad8d44d285ae662e18
Autor:
Max Kam-Kwan Chan, Emily Lok-Yiu Chan, Zoey Zeyuan Ji, Alex Siu-Wing Chan, Chunjie Li, Kam-Tong Leung, Ka-Fai To, Patrick Ming-Kuen Tang
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 2, Pp 316-343 (2023)
Transforming growth factor-β (TGF-β) signaling is an important pathway for promoting the pathogenesis of inflammatory diseases, including cancer. The roles of TGF-β signaling are heterogeneous and versatile in cancer development and progression, b
Externí odkaz:
https://doaj.org/article/f66b695eb39a44d683eec8cd54acc160
Autor:
Leona Yuen-Ling Leung, Hon-Lon Tam, Isaac Sze-Him Leung, Alex Siu-Wing Chan, Yueheng Yin, Xiubin Zhang, Aimei Mao, Pak-Leng Cheong
Publikováno v:
Healthcare, Vol 12, Iss 8, p 844 (2024)
Perceived health and distresses are associated with the practice of lifestyle modifications, which increases the risk of diabetes and hypertension-related complications. This study aimed to define the characteristics and distribution of perceived hea
Externí odkaz:
https://doaj.org/article/6cf560e70e474d57bbf6c177aea24f25
Autor:
Zoey Zeyuan Ji, Max Kam-Kwan Chan, Alex Siu-Wing Chan, Kam-Tong Leung, Xiaohua Jiang, Ka-Fai To, Yi Wu, Patrick Ming-Kuen Tang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and anti-cancer activities are reported, including not only angiogenesis, extra
Externí odkaz:
https://doaj.org/article/a52ec436a9d74b35b7278bb97071615b
Autor:
Vivian Weiwen Xue, Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Alex Siu-Wing Chan, Travis Hoi-Wai To, Justin Shing-Yin Chung, Francis Mussal, Eric W.-F. Lam, Chunjie Li, Ka-Fai To, Kam-Tong Leung, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 26-37 (2021)
Mincle is essential for tumor-associated macrophage (TAM)-driven cancer progression and represents a potential immunotherapeutic target for cancer. Nevertheless, the lack of a specific inhibitor has largely limited its clinical translation. Here, we
Externí odkaz:
https://doaj.org/article/1ce12fdf1f614834a957f8ffa6de827e
Autor:
Philip Chiu‐Tsun Tang, Jeff Yat‐Fai Chung, Vivian Wei‐wen Xue, Jun Xiao, Xiao‐Ming Meng, Xiao‐Ru Huang, Shuang Zhou, Alex Siu‐Wing Chan, Anna Chi‐Man Tsang, Alfred Sze‐Lok Cheng, Tin‐Lap Lee, Kam‐Tong Leung, Eric W.‐F. Lam, Ka‐Fai To, Patrick Ming‐Kuen Tang, Hui‐Yao Lan
Publikováno v:
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Cancer‐associated fibroblasts (CAFs) are important in tumor microenvironment (TME) driven cancer progression. However, CAFs are heterogeneous and still largely underdefined, better understanding their origins will identify new therapeutic
Externí odkaz:
https://doaj.org/article/88a2b3b2105e4c93a1fe6c6dfeb41b23
Autor:
Jacqueline Mei-Chi Ho, Arnold Yu-Lok Wong, Veronika Schoeb, Alex Siu-Wing Chan, Patrick Ming-Kuen Tang, Frances Kam-Yuet Wong
Publikováno v:
Frontiers in Public Health, Vol 9 (2022)
Traditional discipline-specific training has limitations in facilitating inter-professional communication and collaboration. To address this issue, two local universities in Hong Kong launched an interprofessional team-based learning program to allow
Externí odkaz:
https://doaj.org/article/65e7ca8222b84ca09ac839aa4780f65d
Autor:
Philip Chiu-Tsun Tang, Alex Siu-Wing Chan, Cai-Bin Zhang, Cristina Alexandra García Córdoba, Ying-Ying Zhang, Ka-Fai To, Kam-Tong Leung, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Chronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide, imposing a great burden on the healthcare system. Regrettably, effective CKD therapeutic strategies are yet available due to their elusive pathogenic mechanisms. CKD
Externí odkaz:
https://doaj.org/article/8fec8298e69449439ed9f77520c40e9c
Autor:
Jeff Yat-Fai Chung, Max Kam-Kwan Chan, Jane Siu-Fan Li, Alex Siu-Wing Chan, Philip Chiu-Tsun Tang, Kam-Tong Leung, Ka-Fai To, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7575 (2021)
Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting immunoregulation via controlling the activation, proliferation, and
Externí odkaz:
https://doaj.org/article/5a214bc6c5c24e0e8b28bd92dcd1f763