Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alex Shimozono"'
Autor:
Alex Shimozono, Matt Mahoney, Scott Yeudall, Elizabeth Jaekle, Micah Newton, Rene P.F. Kanters, James A. Sikorski, Kristen Elofson, Evan Crawford, Evan Clark, John T. Gupton, Veronica Moore-Stoll, Will Curry, Wen Juekun, Annie Lane
Publikováno v:
Tetrahedron. 74:7408-7420
Pyrroles and quinolones represent core structures, which are routinely found in both natural and synthetic bioactive substances. Consequently, the development of efficient and regiospecific methods for the preparation of such heterocycles with unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577c67c137ae7b5216e411e8adae8cd2
https://doi.org/10.1016/j.tet.2018.10.078
https://doi.org/10.1016/j.tet.2018.10.078
Autor:
Matt Mahoney, Alex Shimozono, Evan Crawford, Rene P.F. Kanters, James A. Sikorski, Raymond N. Dominey, Jeffrey Noble, Campbell Heese, John T. Gupton, Evan Clark, Daniel C. Fisher, Emma W. Goldman, Carlos Perez Mandry, Joe Ortolani
Publikováno v:
Tetrahedron. 74:2650-2663
Highly functionalized pyrroles with appropriate regiochemical functionality represent an important class of marine natural products and potential drug candidates. We describe herein a detailed study of the reaction of α-aminoacid esters with vinylog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f987d929dbcbe8a737edb9dc6ebe279a
https://doi.org/10.1016/j.tet.2018.04.017
https://doi.org/10.1016/j.tet.2018.04.017
Autor:
Jon Patteson, Ellis Huff, Ahmad J. Obaidullah, James A. Sikorski, Alex Shimozono, John T. Gupton, Evan Crawford, Scott Yeudall, Nakul Telang, Wen Juekun, Cristina C. Rohena, Joe Ortolani, Andrew Harrison, Michael Kimmel, Kristin Lescalleet, Susan L. Mooberry, William Curry, Megan E. Hoerrner, Veronica Moore-Stoll, Katie Lounsbury, Glen E. Kellogg
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:3206-3214
New microtubule depolymerizing agents with potent cytotoxic activities have been prepared with a 5-cyano or 5-oximino group attached to a pyrrole core. The utilization of ortho activation of a bromopyrrole ester to facilitate successful Suzuki-Miyaur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c746da3d09d873926805178613f0d2d1
https://doi.org/10.1016/j.bmc.2017.04.012
https://doi.org/10.1016/j.bmc.2017.04.012
Publikováno v:
Angew Chem Int Ed Engl
A Ni‐catalyzed halogenation of enol triflates was developed and it enables the synthesis of a broad range of alkenyl iodides, bromides, and chlorides under mild reaction conditions. The reaction utilizes inexpensive, bench‐stable Ni(OAc)_2⋅4 H_
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c9b837aeedcdc8e6ee7d401fa56bd5
https://pubmed.ncbi.nlm.nih.gov/31410936
https://pubmed.ncbi.nlm.nih.gov/31410936