Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alex Savchenko"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Graphene, a 2D carbon allotrope, is revolutionizing many biomedical applications due to its unique mechanical, electrical, thermal, and optical properties. When bioengineers realized that these properties could dramatically enhance the performance of
Externí odkaz:
https://doaj.org/article/77dbc7c0ca9242bab5fafbb54ed177d1
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Cardiac tissue engineering requires materials that can faithfully recapitulate and support the native in vivo microenvironment while providing a seamless bioelectronic interface. Current limitations of cell scaffolds include the lack of electrical co
Externí odkaz:
https://doaj.org/article/bc09eb70ccba47efb6d8ffa2fec2ef15
Autor:
Wesley L. McKeithan, Alex Savchenko, Michael S. Yu, Fabio Cerignoli, Arne A. N. Bruyneel, Jeffery H. Price, Alexandre R. Colas, Evan W. Miller, John R. Cashman, Mark Mercola
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The ability to produce unlimited numbers of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) harboring disease and patient-specific gene variants creates a new paradigm for modeling congenital heart diseases (CHDs) and predictin
Externí odkaz:
https://doaj.org/article/dd6ff2dfd36f4a7aa83cff65a91e103a
Autor:
Sonia Albini, Paula Coutinho, Barbora Malecova, Lorenzo Giordani, Alex Savchenko, Sonia Vanina Forcales, Pier Lorenzo Puri
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 661-670 (2013)
Direct generation of a homogeneous population of skeletal myoblasts from human embryonic stem cells (hESCs) and formation of three-dimensional contractile structures for disease modeling in vitro are current challenges in regenerative medicine. Previ
Externí odkaz:
https://doaj.org/article/1a08573400e94c8bb31245094c338b91
Autor:
Abby Matt, Hongwu Liang, Matthew Fishman, Elena Gracheva, Fei Wang, Xinyuan Zhang, Alex Savchenko, Elena Molokanova, Chao Zhou
Publikováno v:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e910bfceffe71090d63813c12ccb1530
https://doi.org/10.1117/12.2652964
https://doi.org/10.1117/12.2652964
Autor:
Christopher K. Glass, Ty D. Troutman, Alysson R. Muotri, Jason P. Lerch, Yohei Abe, Sicong Wang, Bradley Voytek, Jason S. Seidman, Spencer M. Moore, Hoonkyo Suh, Alex Savchenko, Daehoon Lee, Josh Stender, Richard Gao, Jacob Ellegood
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-12 (2019)
Translational Psychiatry
Translational Psychiatry
SETD5, a gene linked to intellectual disability (ID) and autism spectrum disorder (ASD), is a member of the SET-domain family and encodes a putative histone methyltransferase (HMT). To date, the mechanism by which SETD5 haploinsufficiency causes ASD/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece683fdc25c9e07742eedf9e3a8ddb6
https://doi.org/10.1038/s41398-018-0344-y
https://doi.org/10.1038/s41398-018-0344-y
Autor:
Fang Xie, Joseph R. Delaney, Alex Savchenko, Jacqueline M. Ward, Vikram G. Shakkottai, David D. Bushart, Pawel M. Switonski, Mandheer Wadhwa, Albert R. La Spada, Chenchen Niu, Johan Auwerx, Colleen A. Stoyas, Mi bo Tang, Karim Gariani, Akshay Alaghatta, Terry Gaasterland, Haoran Huang
Publikováno v:
Neuron
Neuron, Vol. 105, No 4 (2020) pp. 630-644.e9
Neuron, Vol. 105, No 4 (2020) pp. 630-644.e9
Sirtuin 1 (Sirt1) is a NAD(+)-dependent deacetylase capable of countering age-related neurodegeneration, but the basis of Sirt1 neuroprotection remains elusive. Spinocerebellar ataxia type 7 (SCA7) is an inherited CAG-polyglutamine repeat disorder. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b251328d58337bf93c1880757bdd09
https://pubmed.ncbi.nlm.nih.gov/31859031
https://pubmed.ncbi.nlm.nih.gov/31859031
Autor:
Mark Mercola, Fabio Cerignoli, Juan C. del Álamo, Rolf Bodmer, Alex Savchenko, Ricardo Serrano, Derek Lemons
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863:1717-1727
Cardiac drug discovery is hampered by the reliance on non-human animal and cellular models with inadequate throughput and physiological fidelity to accurately identify new targets and test novel therapeutic strategies. Similarly, adverse drug effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd28b1cd0c8117690bf33b6906e299c
https://doi.org/10.1016/j.bbamcr.2016.03.003
https://doi.org/10.1016/j.bbamcr.2016.03.003
Autor:
Dries A.M. Feyen, Franck Potet, Kevin J. Sampson, Daniel A. Ryan, Wesley L. McKeithan, Alfred L. George, Michelle Vu, Jorge Gomez-Galeno, Ricardo Serrano, Arne A. N. Bruyneel, Mark Mercola, Robert S. Kass, John R. Cashman, Karl J. Okolotowicz, Alex Savchenko
Publikováno v:
Cell Stem Cell
Modelling cardiac disorders with human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes is a new paradigm for preclinical testing of candidate therapeutics. However, disease-relevant physiological assays can be complex, and the use of hiP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09cee085acf16a9f1c8839243162c43
https://doi.org/10.1016/j.stem.2020.08.003
https://doi.org/10.1016/j.stem.2020.08.003
Autor:
Volodymyr Cherkas, Gary B. Braun, Yury I. Miller, Alex Savchenko, Chao Liu, Alexander M. Kleschevnikov, Elena Molokanova
Publikováno v:
Science advances, vol 4, iss 5
Science Advances
Science Advances
This study presents a novel graphene-based optoelectronic platform for noninvasive optical stimulation of genetically intact cells
Noninvasive stimulation of cells is crucial for the accurate examination and control of their function both at the
Noninvasive stimulation of cells is crucial for the accurate examination and control of their function both at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df4865815866abc4cd3049eb0689388
https://escholarship.org/uc/item/0gj2539m
https://escholarship.org/uc/item/0gj2539m
