Targeting of Aberrant alpha v beta 6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells

Autor: Ana C. Parente-Pereira, Jose A. Costa-Guerra, Sadaf Ghaem-Maghami, Shobhit Saxena, David M. Davies, Sabari Vallath, Lynsey M. Whilding, John Maher, Y. Vincent Kao, Tomasz Zabinski, Shelia M. Violette, Alex Romain, Hiroaki Itamochi, Roseanna Maria Petrovic, John Marshall

Publikováno v: Whilding, L M, Parente Pereira, A C, Zabinski, T, Davies, D M, Petrovic, R, Kao, V, Saxena, S A, Romain, A, Costa-Guerra, J A, Violette, S, Itamochi, H, Ghaem-Maghami, S, Vallath, S, Marshall, J F & Maher, J 2017, ' Targeting of aberrant αvβ6 integrin expression in solid tumors using chimeric antigen receptor-engineered T-cells ', Molecular Therapy, vol. 25, no. 1, pp. 259-273 . https://doi.org/10.1016/j.ymthe.2016.10.012

Expression of the αvβ6 integrin is upregulated in several solid tumors. By contrast, physiologic expression of this epithelial-specific integrin is restricted to development and epithelial re-modeling. Here, we describe for the first time the devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdad42c103c127ac3618e7d1c969fcd
http://hdl.handle.net/10044/1/49361

Freak shows?

Autor: Alex Romain

Publikováno v: BMJ. :c6787

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96edf6668c3cb4a4e8194467c214bea9
https://doi.org/10.1136/sbmj.c6787

Medicine in science fiction

Autor: Alex Romain

Publikováno v: BMJ. :c5057

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66cbd4bf7a0321946ff27f3f9f31af00
https://doi.org/10.1136/sbmj.c5057