Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Alex R Rinehart"'
Autor:
Raphael J Landovitz, Sue Li, Beatriz Grinsztejn, Halima Dawood, Albert Y Liu, Manya Magnus, Mina C Hosseinipour, Ravindre Panchia, Leslie Cottle, Gordon Chau, Paul Richardson, Mark A Marzinke, Craig W Hendrix, Susan H Eshleman, Yinfeng Zhang, Elizabeth Tolley, Jeremy Sugarman, Ryan Kofron, Adeola Adeyeye, David Burns, Alex R Rinehart, David Margolis, William R Spreen, Myron S Cohen, Marybeth McCauley, Joseph J Eron
Publikováno v:
PLoS Medicine, Vol 15, Iss 11, p e1002690 (2018)
BACKGROUND:Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed for HIV treatment and prevention. CAB is formulated both as an immediate-release oral tablet for daily administration and as a long-acting injectable suspens
Externí odkaz:
https://doaj.org/article/830d37bc7c0d4f32b2594bc89a7448f5
Autor:
Jessica M. Fogel, Estelle Piwowar-Manning, Amber Moser, Tinia Hill, Shahnaz Ahmed, Vanessa Cummings, Heba H. Mostafa, Zhe Wang, Andrea Jennings, Jorge A. Gallardo-Cartagena, María Inés Figueroa, Marty St Clair, Alex R. Rinehart, Adeola Adeyeye, James F. Rooney, Myron S. Cohen, Beatriz Grinsztejn, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Detection of HIV infection may be challenging in persons using long-acting cabotegravir (CAB-LA) pre-exposure prophylaxis (PrEP) due to viral suppression and reduced/delayed antibody production. We evaluated two point-of-care tests for detec
Externí odkaz:
https://doaj.org/article/0ec30651f1934244afc8909a571ed9c4
Autor:
Christina Psaros, Georgia R. Goodman, Jasper S. Lee, Whitney Rice, Colleen F. Kelley, Temitope Oyedele, Lara E. Coelho, Nittaya Phanuphak, Yashna Singh, Keren Middelkoop, Sam Griffith, Marybeth McCauley, James Rooney, Alex R. Rinehart, Jesse Clark, Vivian Go, Jeremy Sugarman, Sheldon D. Fields, Adeola Adeyeye, Beatriz Grinsztejn, Raphael J. Landovitz, Steven A. Safren, the HPTN 083‐02 Study Team
Publikováno v:
Journal of the International AIDS Society, Vol 27, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction HPTN 083 demonstrated the superiority of long‐acting cabotegravir (CAB‐LA) versus daily oral emtricitabine/tenofovir disoproxil fumarate (TDF/FTC) as pre‐exposure prophylaxis (PrEP) among cisgender men and transgender wome
Externí odkaz:
https://doaj.org/article/98512b389e2b4527adca150c40933567
Autor:
Mark A. Marzinke, Jessica M. Fogel, Zhe Wang, Estelle Piwowar-Manning, Ryan Kofron, Amber Moser, Pradip Bhandari, Ryann Gollings, Lane R. Bushman, Lei Weng, Elias K. Halvas, John Mellors, Peter L. Anderson, Deborah Persaud, Craig W. Hendrix, Marybeth McCauley, Alex R. Rinehart, Marty St Clair, Susan L. Ford, James F. Rooney, Adeola Adeyeye, Suwat Chariyalertsak, Kenneth Mayer, Roberto C. Arduino, Myron S. Cohen, Beatriz Grinsztejn, Brett Hanscom, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d8df327421cf8163825ff7dce97986
https://doi.org/10.1128/aac.00053-23
https://doi.org/10.1128/aac.00053-23
Autor:
Tonia Poteat, Supriya Sarkar, Leigh Ragone, Keith Rawlings, Alex R Rinehart, Jennifer N Hill, Kyli Gallington, Karin S Coyne, Vani Vannappagari
Publikováno v:
Open Forum Infectious Diseases. 9
Background Use of daily oral HIV pre-exposure prophylaxis (DO PrEP) has increased steadily in the past several years, but patterns of racial disparities have emerged in PrEP uptake. Although Black and Hispanic people are disproportionately affected b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82cf4d089f7f890226e2da29dd47fd7d
https://doi.org/10.1093/ofid/ofac492.1707
https://doi.org/10.1093/ofid/ofac492.1707
Autor:
Tonia Poteat, Supriya Sarkar, Leigh Ragone, Keith Rawlings, Alex R Rinehart, Jennifer N Hill, Kyli Gallington, Karin S Coyne, Vani Vannappagari
Publikováno v:
Open Forum Infectious Diseases. 9
Background Cisgender women continue to have low pre-exposure prophylaxis (PrEP) uptake in the US, despite making up almost 20% of new HIV infections. The gap between the number of women who would benefit from PrEP and those who use PrEP highlights th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f099143d8b9471a8f38e4607de11c222
https://doi.org/10.1093/ofid/ofac492.055
https://doi.org/10.1093/ofid/ofac492.055
Autor:
Travis Sanchez, S Wilson Beckham, Marissa J Hannah, O Winslow Edwards, Keith Rawlings, Alex R Rinehart, Supriya Sarkar, Patrick S Sullivan, Vani Vannappagari
Publikováno v:
Open Forum Infectious Diseases. 9
Background Daily oral (DO) HIV pre-exposure prophylaxis (PrEP) effectively prevents HIV acquisition, but few men who have sex with men (MSM) currently use it. Newer options, such as on-demand (OD) oral and long-acting injectable (LA) PrEP may improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8343a645734c2e28b6676a16ee54b03
https://doi.org/10.1093/ofid/ofac492.1711
https://doi.org/10.1093/ofid/ofac492.1711
Autor:
Adeola Adeyeye, Myron S. Cohen, Namandjé N. Bumpus, Sue Li, Halima Dawood, Craig W. Hendrix, Alex R. Rinehart, Irene Kuo, Mina C. Hosseinipour, Joseph S Eron, Albert Y. Liu, Gordon Chau, Ravindre Panchia, Raphael J. Landovitz, Herana Kamal Seneviratne, Allyson N. Hamlin, Marybeth McCauley, Leslie Cottle, Beatriz Grinsztejn
Publikováno v:
ACS Pharmacology & Translational Science
ACS pharmacology & translational science, vol 4, iss 1
ACS pharmacology & translational science, vol 4, iss 1
Cabotegravir (CAB) is an integrase strand-transfer inhibitor of HIV that has proven effective for HIV treatment and prevention in a long-acting injectable formulation, typically preceded by an oral formulation lead-in phase. Previous in vitro studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb41c03a688603118f1afe88b214ddc9
http://europepmc.org/articles/PMC7888308
http://europepmc.org/articles/PMC7888308
Autor:
Sue Li, Craig W. Hendrix, Joseph J. Eron, Albert Y. Liu, Mark A. Marzinke, Paul G. Richardson, Alex R. Rinehart, Marybeth McCauley, Adeola Adeyeye, Susan H. Eshleman, Gordon Chau, Manya Magnus, Beatriz Grinsztejn, Ravindre Panchia, Raphael J. Landovitz, David N. Burns, Halima Dawood, Ryan Kofron, Myron S. Cohen, Leslie Cottle, David Margolis, Mina C. Hosseinipour
Publikováno v:
The Lancet HIV. 7:e472-e481
Summary Background Long-acting injectable cabotegravir is a novel integrase inhibitor currently in advanced clinical development for HIV prevention and treatment. We aimed to assess the terminal phase pharmacokinetics and safety of long-acting inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13b481030cc247184efe99a76a79f30
https://doi.org/10.1016/s2352-3018(20)30106-5
https://doi.org/10.1016/s2352-3018(20)30106-5
Autor:
Sinead Delany-Moretlwe, James P. Hughes, Peter Bock, Samuel Gurrion Ouma, Portia Hunidzarira, Dishiki Kalonji, Noel Kayange, Joseph Makhema, Patricia Mandima, Carrie Mathew, Elizabeth Spooner, Juliet Mpendo, Pamela Mukwekwerere, Nyaradzo M. Mgodi, Patricia Nahirya Ntege, Gonasagrie Nair, Clemensia Nakabiito, Harriet Nuwagaba-Biribonwoha, Ravindre Panchia, Nishanta Singh, Bekezela Siziba, Jennifer Farrior, Scott Rose, Rebecca Berhanu, Peter L Anderson, Yaw Agyei, Susan H. Eshleman, Mark A. Marzinke, Estelle Piwowar-Manning, Craig W. Hendrix, Aida Asmelash, Francesca Conradie, Michelle Moorhouse, Paul Richardson, Stephanie Beigel-Orme, Lynda Emel, Kevin Bokoch, Rhonda White, Sybil Hosek, Elizabeth Tolley, Nirupama Sista, Katherine Shin, Adeola Adeyeye, James Rooney, Alex R. Rinehart, William R Spreen, Kimberly Smith, Brett Hanscom, Myron S. Cohen, Mina C. Hosseinipour
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e631c6ed136a4d12a8ae559223b5e62d
https://doi.org/10.2139/ssrn.4066619
https://doi.org/10.2139/ssrn.4066619