Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alex Quan"'
Autor:
Nan Li, Alex Quan, Dan Li, Jiajia Pan, Hua Ren, Gerard Hoeltzel, Natalia de Val, Dana Ashworth, Weiming Ni, Jing Zhou, Sean Mackay, Stephen M. Hewitt, Raul Cachau, Mitchell Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Glypican-1 (GPC1) expression is elevated in pancreatic cancer and has been exploited as a therapeutic target. Here the authors report the development of VHH nanobody-based CAR-T cells targeting GPC1, showing anti-tumor activity in pancreatic cancer p
Externí odkaz:
https://doaj.org/article/a61d87f106544eda8b190f53207ab475
Autor:
PHAM, ALEX-QUAN
Publikováno v:
Poetry, 2015 Jul 01. 206(4), 377-381.
Externí odkaz:
https://www.jstor.org/stable/43592773
Publikováno v:
Cancer Research. 83:4103-4103
Heterogeneous antigen expression is a key barrier influencing the activity of chimeric antigen receptor (CAR) T cells in solid tumors. Here, we developed CAR T cells targeting glypican-1 (GPC1), an oncofetal antigen expressed in pancreatic cancer. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96ce56301cf49c62ff23e001e7f048c
https://doi.org/10.1158/1538-7445.am2023-4103
https://doi.org/10.1158/1538-7445.am2023-4103
Autor:
Vitaly Vodyanoy, Srikumar Sinnarajah, Ben A. Bahr, Randy A. Hall, Vishnu Suppiramaniam, Markus Kessler, Alex Quan
Publikováno v:
Neuroscience Letters. 217:179-183
Heparin was found to bind to alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and to alter their functional properties. AMPA receptors solubilized in 0.4% Triton X-100 bound to a heparin-agarose column and were eluted by 0.4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09c38e292ffcfcd5640f9763b6229af
https://doi.org/10.1016/0304-3940(96)12984-0
https://doi.org/10.1016/0304-3940(96)12984-0
Publikováno v:
Neurochemical Research. 21:963-968
The binding properties of membrane-bound or solubilized AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid)-type glutamate receptors from rat brain were tested following exposure to ultraviolet (UV) radiation or incubation with the thiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d542678f650550aa044bff50599d9af5
https://doi.org/10.1007/bf02532347
https://doi.org/10.1007/bf02532347
Akademický článek
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Publikováno v:
Scopus-Elsevier
The effects of cyclothiazide, a drug which blocks AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor desensitization, were tested on binding of [3HAMPA to rat brain membranes. Cyclothiazide reduced [3HAMPA binding by lowering the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524a665e2dd17a045935baa6a57d24a6
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027332679&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027332679&partnerID=MN8TOARS
Akademický článek
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