Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Alex Paterson"'
Autor:
David C. Emery, Maria Davies, Tanya L. Cerajewska, Jelena Taylor, Mae Hazell, Alex Paterson, Shelley J. Allen-Birt, Nicola X. West
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionAlzheimer’s (AD) and Parkinson’s disease (PD) are neurodegenerative conditions characterized by incremental deposition of β-amyloid (Aβ) and α-synuclein in AD and PD brain, respectively, in relatively conserved patterns. Both are a
Externí odkaz:
https://doaj.org/article/a7cd303dce9c44d7a90d409cec47a004
Autor:
Mingkwan Greenwood, Benjamin T. Gillard, Rizwan Farrukh, Alex Paterson, Ferdinand Althammer, Valery Grinevich, David Murphy, Michael P. Greenwood
Publikováno v:
Molecular Metabolism, Vol 63, Iss , Pp 101542- (2022)
Objectives: Dynamic changes to neuropeptide hormone synthesis and secretion by hypothalamic neuroendocrine cells is essential to ensure metabolic homeostasis. The specialised molecular mechanisms that allow neuroendocrine cells to synthesise and secr
Externí odkaz:
https://doaj.org/article/643d551f0e874f83a8efb9ddbc1bffd1
Autor:
Fernando Alvira-Iraizoz, Benjamin T. Gillard, Panjiao Lin, Alex Paterson, Audrys G. Pauža, Mahmoud A. Ali, Ammar H. Alabsi, Pamela A. Burger, Naserddine Hamadi, Abdu Adem, David Murphy, Michael P. Greenwood
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-21 (2021)
Fernando Alvira-Iraizoz and Benjamin T. Gillard et al. comprehensively catalogue the kidney transcriptome and proteome of dromedary camels in response to chronic dehydration stress and subsequent acute rehydration. Their results suggest that the supp
Externí odkaz:
https://doaj.org/article/d8616ab913bc4af5a29d5f269a823c7b
Autor:
Andrew Martin, Andre S. Mecawi, Vagner R. Antunes, Song T. Yao, Jose Antunes-Rodrigues, Julian F. R. Paton, Alex Paterson, Michael Greenwood, Olivera Šarenac, Bojana Savić, Nina Japundžić-Žigon, David Murphy, Charles C. T. Hindmarch
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
The chronically increased blood pressure characteristic of essential hypertension represents an insidious and cumulative risk for cardiovascular disease. Essential hypertension is a multifactorial condition, with no known specific aetiology but a str
Externí odkaz:
https://doaj.org/article/b19027e0b37e45ec9c6f9a93660e4bcb
Autor:
David C. Emery, Tanya L. Cerajewska, Joon Seong, Maria Davies, Alex Paterson, Shelley J. Allen-Birt, Nicola X. West
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
The use of Next Generation Sequencing (NGS) techniques has generated a wide variety of blood microbiome data. Due to the large variation in bacterial DNA profiles between studies and the likely high concentrations of cell-free bacterial DNA in the bl
Externí odkaz:
https://doaj.org/article/cd36da9fdd564fbf89183bc9ef81423f
Autor:
Ghadir Elsamad, Andre Mecawi, Audrys Pauža, Benjamin Gillard, Alex Paterson, Victor Duque, Olivera Šarenac, Nina Žigon, Mingkwan Greenwood, Michael Greenwood, David Murphy
Ageing is associated with altered neuroendocrine function. In the context of the hypothalamic supraoptic nucleus, which makes the antidiuretic hormone vasopressin, ageing alters acute responses to hyperosmotic cues, rendering the elderly more suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd624989262ac0788c06129d1e758b1a
https://doi.org/10.21203/rs.3.rs-2463463/v1
https://doi.org/10.21203/rs.3.rs-2463463/v1
Autor:
Matthew T. Birnie, Alex Paterson, Diana A. Stavreva, YM Kershaw, Becky L. Conway-Campbell, Audrys G Pauza, Songjoon Baek, David Murphy, Mark F. Rogers, Benjamin P. Flynn, Sohyoung Kim, Gordon L. Hager, Stafford L. Lightman
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009737 (2021)
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynam
Autor:
Mingkwan Greenwood, Michael P Greenwood, Alex Paterson, Audrys G. Pauža, André S. Mecawi, David Murphy, Charles C.T. Hindmarch
Publikováno v:
Journal of Neuroendocrinology. 33
The hypothalamic supraoptic nucleus (SON) is a core osmoregulatory control centre that deciphers information about the metabolic state of the organism and orchestrates appropriate homeostatic (endocrine) and allostatic (behavioural) responses. We hav
Autor:
Panjiao Lin, Benjamin Thomas Gillard, Michael P Greenwood, Naserddine Hamadi, Alex Paterson, Ammar H. Alabsi, Mahmoud A. Ali, David Murphy, Audrys G. Pauža, Abdu Adem, Fernando Alvira-Iraizoz, Pamela A. Burger
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-21 (2021)
Communications Biology
Communications Biology
The Arabian camel (Camelus dromedarius) is the most important livestock animal in arid and semi-arid regions and provides basic necessities to millions of people. In the current context of climate change, there is renewed interest in the mechanisms t
Autor:
Christopher R. Neal, Judith Mantell, Janine McCaughey, Alex Paterson, David J. Stephens, Kate J. Heesom, Nicola L. Stevenson
Complex machinery is required to drive secretory cargo export from the endoplasmic reticulum, an essential process in eukaryotic cells. In vertebrates, the Mia3 gene encodes two major forms of Transport ANd Golgi Organization Protein 1 (TANGO1S and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37794b4b51d48eb287582852d8e3ef86
https://doi.org/10.1101/2021.02.24.432632
https://doi.org/10.1101/2021.02.24.432632