Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alex P. McLatchie"'
Autor:
Joanna C. Dawes, Philip Webster, Barbara Iadarola, Claudia Garcia-Diaz, Marian Dore, Bruce J. Bolt, Hamlata Dewchand, Gopuraja Dharmalingam, Alex P. McLatchie, Jakub Kaczor, Juan J. Caceres, Alberto Paccanaro, Laurence Game, Simona Parrinello, Anthony G. Uren
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Ligation-mediated PCR protocols have diverse uses including the identification of integration sites of insertional mutagens, integrating vectors and naturally occurring mobile genetic elements. For approaches that employ NGS seque
Externí odkaz:
https://doaj.org/article/cdb46adc21fd43509b19e5cc6b2b40e7
Autor:
Alex P McLatchie, Hollie Burrell-Saward, Elmarie Myburgh, Michael D Lewis, Theresa H Ward, Jeremy C Mottram, Simon L Croft, John M Kelly, Martin C Taylor
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2571 (2013)
Human African trypanosomiasis is caused by infection with parasites of the Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan Africa. Development of new drugs is hampered by the limitations of current rodent model
Externí odkaz:
https://doaj.org/article/89956e7587f44366b48ce7e39be94ae3
Autor:
Elmarie Myburgh, Jonathan A Coles, Ryan Ritchie, Peter G E Kennedy, Alex P McLatchie, Jean Rodgers, Martin C Taylor, Michael P Barrett, James M Brewer, Jeremy C Mottram
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2384 (2013)
HUMAN AFRICAN TRYPANOSOMIASIS (HAT) MANIFESTS IN TWO STAGES OF DISEASE: firstly, haemolymphatic, and secondly, an encephalitic phase involving the central nervous system (CNS). New drugs to treat the second-stage disease are urgently needed, yet test
Externí odkaz:
https://doaj.org/article/d8f63ebc485e4ac5958df2b230b0fd99
Autor:
Michael D, Lewis, Amanda, Fortes Francisco, Martin C, Taylor, Hollie, Burrell-Saward, Alex P, McLatchie, Michael A, Miles, John M, Kelly
Publikováno v:
Cellular Microbiology
Summary Chronic Trypanosoma cruzi infections lead to cardiomyopathy in 20–30% of cases. A causal link between cardiac infection and pathology has been difficult to establish because of a lack of robust methods to detect scarce, focally distributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1a25bf7e49c6c85bcc91f4ee47acd00
https://pubmed.ncbi.nlm.nih.gov/24712539
https://pubmed.ncbi.nlm.nih.gov/24712539
Autor:
Martin C. Taylor, Michael P. Barrett, Jonathan A. Coles, James M. Brewer, Jeremy C. Mottram, Ryan Ritchie, Alex P. McLatchie, Jean Rodgers, Elmarie Myburgh, Peter G. E. Kennedy
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2384 (2013)
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2384 (2013)
Human African trypanosomiasis (HAT) manifests in two stages of disease: firstly, haemolymphatic, and secondly, an encephalitic phase involving the central nervous system (CNS). New drugs to treat the second-stage disease are urgently needed, yet test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2957ebe7e9f31a02d7debbebd07cd22d
https://researchonline.lshtm.ac.uk/id/eprint/1366954/1/info_doi%2F10.1371%2Fjournal.pntd.0002384
https://researchonline.lshtm.ac.uk/id/eprint/1366954/1/info_doi%2F10.1371%2Fjournal.pntd.0002384
Publikováno v:
Molecular Microbiology
Bloodstream-form Trypanosoma brucei acquire iron by receptor-mediated endocytosis of host transferrin. However, the mechanism(s) by which iron is then transferred from the lysosome to the cytosol are unresolved. Here, we provide evidence for the invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aee55ab53b85c87d21d982002fc87af
https://researchonline.lshtm.ac.uk/id/eprint/967533/1/mmi12285.pdf
https://researchonline.lshtm.ac.uk/id/eprint/967533/1/mmi12285.pdf