Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Alex Nechiporuk"'
Autor:
Timothy Erickson, Clive P Morgan, Jennifer Olt, Katherine Hardy, Elisabeth Busch-Nentwich, Reo Maeda, Rachel Clemens, Jocelyn F Krey, Alex Nechiporuk, Peter G Barr-Gillespie, Walter Marcotti, Teresa Nicolson
Publikováno v:
eLife, Vol 6 (2017)
Transmembrane O-methyltransferase (TOMT/LRTOMT) is responsible for non-syndromic deafness DFNB63. However, the specific defects that lead to hearing loss have not been described. Using a zebrafish model of DFNB63, we show that the auditory and vestib
Externí odkaz:
https://doaj.org/article/8c67b3aa4fc342c1bcf127fb9e97b312
Autor:
Hannah M. Olson, Alex Nechiporuk
Publikováno v:
Dev Biol
Collective cell migration is a process where cohorts of cells exhibit coordinated migratory behavior. During individual and collective cellular migration, cells must extend protrusions to interact with the extracellular environment, sense chemotactic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8131bd1bb394490604dd22b60b44ed5
https://doi.org/10.1016/j.ydbio.2020.10.007
https://doi.org/10.1016/j.ydbio.2020.10.007
Peripheral somatosensory neurons innervate the skin and sense the environment. Loss of skin innervation, often caused by the “dying back” of distal somatosensory axons, is a common side effect of drug-induced peripheral neuropathies (DIPNs) and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fe364551dcb9903109ab153355fe0dd
https://doi.org/10.1101/2021.09.13.460106
https://doi.org/10.1101/2021.09.13.460106
Autor:
Hannah M. Olson, Alex Nechiporuk
Publikováno v:
Developmental Cell. 46:674-676
The extracellular matrix plays both positive and negative roles in growth factor diffusion, a process critical for organ formation. In this issue of Developmental Cell, Wang et al. (2018) identify the extracellular matrix protein Anosmin1 as a key re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec3d51632c5acad4fc0e9ec28de034c
https://doi.org/10.1016/j.devcel.2018.09.004
https://doi.org/10.1016/j.devcel.2018.09.004
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The trafficking mechanisms and transcriptional targets downstream of long-range neurotrophic factor ligand/receptor signaling that promote axon growth are incompletely understood. Zebrafish carrying a null mutation in a neurotrophic factor receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8fe33d06f85e683b198a9f1b02e560
https://elifesciences.org/articles/46092
https://elifesciences.org/articles/46092
Autor:
Rebecca A.S. Palu, H. Joseph Yost, Xiaoying Bai, Kazuyuki Hoshijima, Haley Jackson, Yi Chu Su, Brent W. Bisgrove, David Grunwald, Alex Nechiporuk, Leonard I. Zon, Hannah A. Grunwald, Michael J. Jurynec
Publikováno v:
Development
Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the Polymerase Associated Factor 1 Complex (Paf1C) is required to maintain multipotent progenitors of the neural crest (NC) lineage in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b5c40986fce48d1b91fe2b6d6e4f5a
https://doi.org/10.1242/dev.180133
https://doi.org/10.1242/dev.180133
In many cases, axon growth and guidance are driven by pioneer axons, the first axons to grow in a particular region. Despite their dynamic pathfinding capabilities and developmental importance, there are very few pioneer neuron specific markers and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e8b1cb20802b32705ace5d1946589c
Autor:
Sarah D. Ackerman, Breanne L. Harty, Ben A. Barres, Alex Nechiporuk, Thomas O'Reilly-Pol, Catherine M. Drerup, Ryan S. Gray, Stephen L. Johnson, Amy L. Herbert, Kelly R. Monk, Meng-meng Fu
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Oligodendrocytes in the central nervous system produce myelin, a lipid-rich, multilamellar sheath that surrounds axons and promotes the rapid propagation of action potentials. A critical component of myelin is myelin basic protein (MBP), expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf48de6c26ecd8991bb74096b0439ba5
https://doi.org/10.1073/pnas.1711088114
https://doi.org/10.1073/pnas.1711088114
Autor:
Jocelyn F. Krey, Katherine Hardy, Peter G. Barr-Gillespie, Clive P Morgan, Teresa Nicolson, Walter Marcotti, Reo Maeda, Rachel Clemens, Timothy B. Erickson, Jennifer Olt, Alex Nechiporuk, Elisabeth M. Busch-Nentwich
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Transmembrane O-methyltransferase (TOMT/LRTOMT) is responsible for non-syndromic deafness DFNB63. However, the specific defects that lead to hearing loss have not been described. Using a zebrafish model of DFNB63, we show that the auditory and vestib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62517a4a3e48fed184a58bb26b30ec3
https://www.repository.cam.ac.uk/handle/1810/277291
https://www.repository.cam.ac.uk/handle/1810/277291