Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alex N. Tinega"'
Autor:
Cormac J. Lucas, Bennett J. Davenport, Kathryn S. Carpentier, Alex N. Tinega, Thomas E. Morrison
Publikováno v:
J Virol
Alphaviruses infect cells by a low pH-dependent fusion reaction between viral and host cell membranes that is mediated by the viral E1 glycoprotein. Most reported alphavirus E1 sequences include two phenylalanines (F87 and F95) in the fusion loop, ye
Autor:
Angela M. Mitchell, Shaodong Dai, Michael T. Falta, Lisa A. Maier, Shaikh M. Atif, Lan Chen, Andrew P. Fontenot, Alex N. Tinega, Sarah A. Greaves, Johan Grunewald, Clemencia Pinilla, Yang Wang, Radleigh Santos, Douglas G. Mack, Avinash Ravindran
Publikováno v:
The Journal of experimental medicine. 218(10)
Löfgren’s syndrome (LS) is an acute form of sarcoidosis characterized by a genetic association with HLA-DRB1*03 (HLA-DR3) and an accumulation of CD4+ T cells of unknown specificity in the bronchoalveolar lavage (BAL). Here, we screened related LS-
Autor:
Alex N. Tinega, Allison K. Martin, John W. Kappler, Douglas G. Mack, Lisa A. Maier, Michael T. Falta, Clemencia Pinilla, Frances Crawford, Jeremy Chase Crawford, Li Li, Paul G. Thomas, Shaikh M. Atif, Radleigh Santos, Laurie G. Landry, Maki Nakayama, Andrew P. Fontenot
Publikováno v:
J Clin Invest
Discovering dominant epitopes for T cells, particularly CD4+ T cells, in human immune-mediated diseases remains a significant challenge. Here, we used bronchoalveolar lavage (BAL) cells from HLA-DP2-expressing patients with chronic beryllium disease
Autor:
Ellen L. Burnham, Fabian Wehrmann, Joshua M. Thurman, James C. Lavelle, Colm B. Collins, Alex N. Tinega, Philip L. Simonian
Publikováno v:
Journal of Leukocyte Biology. 99:373-386
γδ T lymphocytes are a unique T cell population with important anti-inflammatory capabilities. Their role in acute lung injury, however, is poorly understood but may provide significant insight into lung-protective mechanisms occurring after injury
Autor:
Roger Pelle, Vishvanath Nene, Simon P. Graham, Michael M. Gicheru, Simon Kang’a, Alex N. Tinega, Evans L. N. Taracha
Publikováno v:
Veterinary Immunology and Immunopathology. 130:107-113
Immunity to the bovine apicomplexan parasite Theileria parva is associated with MHC-I restricted CD8 + T cell responses directed against the intralymphocytic schizont stage of the parasite. A number of schizont-stage antigens that are targets of CD8
Autor:
Alex N. Tinega, Michael T. Falta, Frances Crawford, Clemencia Pinilla, Andrew P. Fontenot, Douglas G. Mack, John W. Kappler, Natalie A. Bowerman
Publikováno v:
Mucosal immunology
Chronic beryllium disease (CBD) is a granulomatous lung disorder that is associated with the accumulation of beryllium (Be)-specific CD4(+) T cells into the lung. Genetic susceptibility is linked to HLA-DPB1 alleles that possess a glutamic acid at po
Autor:
Philippa Marrack, John W. Kappler, Andrew P. Fontenot, Radleigh G. Santos, Alex N. Tinega, Frances Crawford, Michael T. Falta, Gina M. Clayton, Yuxiao Wang, Xuewu Zhang, Marc A. Giulianotti, Lisa A. Maier, Clemencia Pinilla, Douglas G. Mack
Publikováno v:
The Journal of Experimental Medicine
Identification of peptides that form complexes with beryllium and class II HLA molecules and are recognized by CD4+ T cells from patients with chronic beryllium disease.
Chronic beryllium disease (CBD) is a granulomatous disorder characterized b
Chronic beryllium disease (CBD) is a granulomatous disorder characterized b
Autor:
Angela M Mitchell, Michael T Falta, Alex N Tinega, Johan Grunewald, Clemencia Pinilla, Andrew P Fontenot
Publikováno v:
The Journal of Immunology. 196:54.20-54.20
Sarcoidosis is a multisystem disorder which most commonly affects the lungs and involves the accumulation of CD4+ T cells at the sites of disease. The etiology of the disease is unknown, and the lack of a known antigen has hindered the study of disea