Chromosome level assembly and comparative genome analysis confirm lager-brewing yeasts originated from a single hybridization

Autor: Alex N. Salazar, Arthur R. Gorter de Vries, Marcel van den Broek, Nick Brouwers, Pilar de la Torre Cortès, Niels G. A. Kuijpers, Jean-Marc G. Daran, Thomas Abeel

Publikováno v: BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)

Abstract Background The lager brewing yeast, S. pastorianus, is a hybrid between S. cerevisiae and S. eubayanus with extensive chromosome aneuploidy. S. pastorianus is subdivided into Group 1 and Group 2 strains, where Group 2 strains have higher cop

Externí odkaz: https://doaj.org/article/5a4849056bb0414d9769fccd997cbca5

An educational guide for nanopore sequencing in the classroom

Autor: Thomas Abeel, Cristian Aparicio-Maldonado, Anwar Hiralal, Ana Rita Costa, Anna C. Haagsma, Stan J. J. Brouns, Ahmed Mahfouz, Teunke van Rossum, Alex N. Salazar, Christine Anyansi, Franklin L. Nobrega, Rebecca E. McKenzie

Publikováno v: PLOS Computational Biology
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 1, p e1007314 (2020)
PLoS Computational Biology (Print), 16(1)

The last decade has witnessed a remarkable increase in our ability to measure genetic information. Advancements of sequencing technologies are challenging the existing methods of data storage and analysis. While methods to cope with the data deluge a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1b730789165a1e3b60ae0182cfe4c5

Laboratory Evolution of a Saccharomyces cerevisiae × S. eubayanus Hybrid Under Simulated Lager-Brewing Conditions

Autor: Alex N. Salazar, Line H. Kristensen, Nick Brouwers, Liset Jansen, Jack T. Pronk, Arthur R. Gorter de Vries, Maaike A. Voskamp, Marcel van den Broek, Jean-Marc Daran, Aafke C. A. van Aalst, Thomas Abeel

Publikováno v: Frontiers in Genetics, 10
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)

Saccharomyces pastorianus lager-brewing yeasts are domesticated hybrids of S. cerevisiae x S. eubayanus that display extensive inter-strain chromosome copy number variation and chromosomal recombinations. It is unclear to what extent such genome rear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a4469494305443439babd20f11bb35

Chromosome level assembly and comparative genome analysis confirm lager-brewing yeasts originated from a single hybridization

Autor: Pilar de la Torre Cortés, Niels G. A. Kuijpers, Marcel van den Broek, Alex N. Salazar, Thomas Abeel, Nick Brouwers, Jean-Marc Daran, Arthur R. Gorter de Vries

Publikováno v: BMC Genomics, 20(1)
BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)
BMC Genomics

BackgroundThe lager brewing yeast,S. pastorianus, is a hybrid betweenS. cerevisiaeandS. eubayanuswith extensive chromosome aneuploidy.S. pastorianusis subdivided into Group 1 and Group 2 strains, where Group 2 strains have higher copy number and a la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0220ca7ec4fe412fe622e60c46976600
http://resolver.tudelft.nl/uuid:87d4da33-fe2e-43ce-bc8a-ba08ee512b45

Laboratory evolution of aSaccharomyces cerevisiaexS. eubayanushybrid under simulated lager-brewing conditions: genetic diversity and phenotypic convergence

Autor: de Vries Arg, Jansen L, Daran Jg, Alex N. Salazar, Thomas Abeel, van den Broek M, Voskamp Ma, Jack T. Pronk, van Aalst Aca, Nick Brouwers, Kristensen Lh

Saccharomyces pastorianuslager-brewing yeasts are domesticated hybrids ofS. cerevisiaexS. eubayanusthat display extensive inter-strain chromosome copy number variation and chromosomal recombinations. It is unclear to what extent such genome rearrange

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9116d36c5dbfe122d0cbf181bd98273
https://doi.org/10.1101/476929