Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alex Muntendam"'
Autor:
Frans G. Zitman, Frans L A Willekens, Kees Ensing, Guus Essink, Pieternel C. M. Pasker-de Jong, Alex Muntendam, Bas Verwey
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 29:47-53
The relationship between anterograde amnesia, sedation and plasma levels of benzodiazepines was studied prospectively in a group of 24 patients who took an overdose of benzodiazepines. Patients were tested on two sequential days after having taken an
The sheep as a model of preclinical safety and pharmacokinetic evaluations of candidate microbicides
Autor:
Jeremy Nuttall, Nicola Dias, Jonathon D. S. Holt, Lisa C. Rohan, Alex Muntendam, J D Holding, David Cameron, Peter Dreier, Freddy Oostebring
Publikováno v:
Antimicrobial agents and chemotherapy. 59(7)
When developing novel microbicide products for the prevention of HIV infection, the preclinical safety program must evaluate not only the active pharmaceutical ingredient but also the product itself. To that end, we applied several relatively standar
Publikováno v:
Journal of Analytical Toxicology, 28(7), 587-592. Oxford University Press
Impairments in memory and psychomotor function appear to be induced by benzodiazepines not only after long-term use, but also after administration of a single dose. Because it is known on which neurotransmitter system the benzodiazepines exert their
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 34(3), 671-679. ELSEVIER SCIENCE BV
This article describes the development and validation of two fluorescent receptor assays for the hRec-estrogen receptor subtypes alpha and beta. As a labelled ligand an autofluorescent phyto-estrogen (coumestrol) has been used. The estrogen receptor