Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alex M. Spence"'
Autor:
Robert C. Rostomily, Martin Bland, Duc Duong, Alex M. Spence, Mitchel S. Berger, Karen McCormick
Publikováno v:
Neurosurgery. 35:378-388
Fifty-one adult patients with recurrent malignant gliomas were treated in a Phase II trial of multidrug chemotherapy (6-thioguanine, dibromodulcitol, procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, 5-fluorouracil, and hydroxyurea). Thirty
Autor:
G. Evren Keles, Michael D. Prados, Alex M. Spence, Michael W. McDermott, James Fick, Susan M. Chang, Charles B. Wilson, Kenneth W. Culver, Mitchel S. Berger, John Van Gilder
Publikováno v:
Journal of neuro-oncology. 65(3)
To determine the safety and evaluate the efficacy of repeated administration of virus-producing cells (GLI 328) containing the herpes simplex virus thymidine-kinase gene followed by ganciclovir treatment in adults with recurrent glioblastoma multifor
Autor:
Abhineet Chowdhary, Daniel L. Silbergeld, L.R. Sales, Jason K. Rockhill, Alex M. Spence, Robert C. Rostomily
Publikováno v:
Surgical Neurology International
Background: A serious, albeit rare, sequel of therapeutic ionizing radiotherapy is delayed development of a new, histologically distinct neoplasm within the radiation field. Methods: We identified 27 cases, from a 10-year period, of intracranial tumo
Autor:
Robert C. Rostomily, Alex M. Spence, Duc Duong, Karen McCormick, Martin Bland, Mitchel S. Berger
Publikováno v:
Neurosurgery. 35:378
Autor:
Alex M. Spence, Gregory V. Priestley
Publikováno v:
Neuropathology and Applied Neurobiology. 7:63-75
Transplanted lines of seven F-344 (Fischer) rat malignant gliomas induced transplacentally with ethylnitrosourea (ENU) were surveyed by in vivo immunoprotection assays for the presence of tumour rejection antigens. These gliomas were representative o
Publikováno v:
Current Problems in Cancer. 8:1-43
Autor:
Alex M. Spence, Mary M. Herman
Publikováno v:
Mechanisms of Ageing and Development. 2:211-227
While premature aging is traditionally considered the underlying process in progeria, previous studies of post-mortem material have failed to provide compelling support for this concept. Lipofuscin accumulation, a marker of aging in certain tissues,
Publikováno v:
Neuropathology and applied neurobiology. 11(3)
F-344 rats were treated with whole-brain fractionated or unfractionated 137Cs at several time intervals up to 6 weeks before they received intracerebral grafts of an ethylnitrosourea-induced rat astrocytoma (36B-10). Rats treated with a single dose o
Publikováno v:
International journal of radiation oncology, biology, physics. 12(7)
Binding of 3H-misonidazole in hypoxic nonmalignant tissue was investigated in the gerbil stroke model. Cerebral infarcts were produced in male Mongolian gerbils by ligating the right common carotid artery and the severity of the lesions was quantifie
Publikováno v:
Radiation Research. 102:130
3-Amino-2-hydroxypropyl phosphorothioate (WR77913), a less toxic phosphorothioate radioprotector than WR2721, has been labeled with 35S. The biodistribution of a radioprotective dose of 800 mg/kg was determined in C3H mice bearing RIF-1 tumors as a f