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pro vyhledávání: '"Alex M. Hellawell"'
Autor:
Marilyn Harding, Alex M. Hellawell, Jonathan J. Ruprecht, Airlie J. McCoy, Paul G. Crichton, Edmund R.S. Kunji
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 111
'Proceedings of the National Academy of Sciences of the USA ', vol: 111, pages: E426-E434 (2014)
'Proceedings of the National Academy of Sciences of the USA ', vol: 111, pages: E426-E434 (2014)
The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix. The carrier cycles by an unresolved mechanism between the cytoplasmic state, in which the carrier accepts ADP from the cytoplasm, and the ma
Autor:
Daniel J. Müller, Adam Klosin, Alexej Kedrov, Alex M. Hellawell, R. Bill Broadhurst, Edmund R.S. Kunji
Publikováno v:
Structure. 18:39-46
Mitochondrial ADP/ATP carriers are inhibited by two natural compounds, atractyloside (ATR) or carboxy-atractyloside (CATR), which differ by one carboxylate group. The interactions of the inhibitors with the carrier were investigated by single-molecul