Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alex M. Downs"'
Autor:
Alex M. Downs, Julian Gerson, Kaylyn K. Leung, Kevin M. Honeywell, Tod Kippin, Kevin W. Plaxco
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Electrochemical aptamer-based (EAB) sensors support the real-time, high frequency measurement of pharmaceuticals and metabolites in-situ in the living body, rendering them a potentially powerful technology for both research and clinical appl
Externí odkaz:
https://doaj.org/article/1f5dd011f9334c69a5b0be1adec67bf7
Autor:
Mark J Carroll, Nicholas Brown, Craig Goodall, Alex M Downs, Timothy H Sheenan, Kirk E Anderson
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249458 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0175933.].
Externí odkaz:
https://doaj.org/article/36b058df00154a4690bf29886fee0d33
Autor:
Alex M. Downs, Kevin W. Plaxco
Publikováno v:
ACS sensors, vol 7, iss 10
ACS Sens
ACS Sens
The continuous, real-time measurement of specific molecules in situ in the body would greatly improve our ability to understand, diagnose, and treat disease. The vast majority of continuous molecular sensing technologies, however, either (1) rely on
Autor:
Alex M. Downs, Adam Bolotsky, Bryan M. Weaver, Haley Bennett, Nathan Wolff, Ronen Polsky, Philip R. Miller
Publikováno v:
Biosensors and Bioelectronics. 236:115408
Publikováno v:
ELECTROPHORESIS. 40:792-798
Spatial confinement, within cells or micro- and nanofabricated devices, impacts the conformation and binding kinetics of biomolecules. Understanding the role of spatial confinement on molecular behavior is important for comprehending diverse biologic
Autor:
Tod E. Kippin, Julian Gerson, Heinz-Bernhard Kraatz, Alex M. Downs, Kyle L. Ploense, Michael Pham, M. Nur Hossain, Kevin W. Plaxco
Publikováno v:
ACS sensors. 6(6)
Electrochemical aptamer-based sensors enable real-time molecular measurements in the living body. The spatial resolution of these measurements and ability to perform measurements in targeted locations, however, is limited by the length and width of t
Publikováno v:
Analytical chemistry. 92(20)
Recent years have seen the development of a number of biosensor architectures that rely on target binding-induced changes in the rate of electron transfer from an electrode-bound receptor. Most often, the interrogation of these sensors has relied on
Autor:
Timothy H. Sheenan, Craig Goodall, Nick Brown, Alex M. Downs, Kirk E. Anderson, Mark J. Carroll
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249458 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0175933.].
Autor:
Timothy H. Sheenan, Alex M. Downs, Mark J. Carroll, Craig Goodall, Nicholas Brown, Kirk E. Anderson
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175933 (2017)
PLoS ONE
PLoS ONE
Honey bees (Apis mellifera) collect and store both honey and pollen in preserved forms. Pollen storage involves the addition of honey or nectar and oral secretions to pollen granules. It is controversial whether the duration of pollen storage alters