Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alex M. Babcock"'
Autor:
Richard A Bessen, Cameron J Robinson, Davis M Seelig, Christopher P Watschke, Diana Lowe, Harold Shearin, Scott Martinka, Alex M Babcock
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28026 (2011)
Chronic wasting disease (CWD) is an emerging prion disease of free-ranging and captive cervids in North America. In this study we established a rodent model for CWD in Syrian golden hamsters that resemble key features of the disease in cervids includ
Externí odkaz:
https://doaj.org/article/a09f4fba922d4fb2921a4bc8608d1b0f
Autor:
D. Standing, David J. Poulsen, K. Bullshields, Charles M. Paden, Alex M. Babcock, Ernst Schwartz
Publikováno v:
Molecular Therapy. 11(6):899-905
Hippocampal alpha-Ca2+/calmodulin-dependent protein kinase II (alpha-CaMKII) has been implicated in spatial learning, neuronal plasticity, epilepsy, and cerebral ischemia. In the present study, an adeno-associated virus (AAV) vector was designed to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b137a4fe28b18ac427800c58835f15
Publikováno v:
Journal of Neuroscience Research. 67:804-811
Excessive release of glutamate during transient cerebral ischemia initiates a cascade of events that leads to the delayed and selective death of neurons located in the hippocampus. Activity of calcium calmodulin kinase II (CaM kinase), a protein kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930a3422a22179c9711d8a9776db0f69
https://doi.org/10.1002/jnr.10169
https://doi.org/10.1002/jnr.10169
Publikováno v:
Journal of Neuroscience Research. 56:36-43
Calcium/calmodulin-dependent protein kinase II (CaM kinase) activity is inhibited in cultured hippocampal cells following direct application of glutamate. The goal of the present study was to determine if hippocampal regions that undergo delayed cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ec62f552a992318dcbaed837ec8604
https://doi.org/10.1002/(sici)1097-4547(19990401)56:1<36::aid-jnr5>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19990401)56:1<36::aid-jnr5>3.0.co
Autor:
Heidi Graham-Goodwin, Alex M. Babcock
Publikováno v:
Brain Research Bulletin. 42:415-419
A series of experiments was conducted to evaluate the effects of preoperative training on three variations of a spatial working memory task following ischemic damage to the hippocampus. A discrete trial, pair-run procedure in a standard T-maze appara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4cc9610d4304f20f78c5ab5e5146f3
https://doi.org/10.1016/s0361-9230(96)00330-9
https://doi.org/10.1016/s0361-9230(96)00330-9
Publikováno v:
Brain Research. 625:351-354
Previous studies have shown that within 24 h after ischemic insult, gerbils exhibit an increase in locomotor activity. Because activity gradually diminishes to normal levels with repeated testing, it has been argued that this behavior represents a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4354eda5d81fd6e0aa48eaa9b5c27868
https://doi.org/10.1016/0006-8993(93)91081-3
https://doi.org/10.1016/0006-8993(93)91081-3
Publikováno v:
Journal of neuroscience research. 85(4)
Hippocampal alpha-calcium/calmodulin-dependent protein kinase II (alphaCaMKII) has been implicated in neuronal plasticity and spatial learning. In the present experiment, an adeno-associated virus (AAV) vector was designed to express alphaCaMKII driv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2513ce6291d2708d564e129d9d2db5c8
https://pubmed.ncbi.nlm.nih.gov/17171706
https://pubmed.ncbi.nlm.nih.gov/17171706
Autor:
Alex M. Babcock, Chris Barton
Publikováno v:
Brain Research Bulletin. 25:775-777
The tetradecapeptide bombesin is a potent agent in producing hypothermia when injected centrally. Bombesin-induced hypothermia at normal ambient temperature occurs under conditions of food deprivation or insulin-induced hypoglycemia. This experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f86643cf52e1e3f358e912374362b9b
https://doi.org/10.1016/0361-9230(90)90057-7
https://doi.org/10.1016/0361-9230(90)90057-7
Publikováno v:
Brain research. 705(1-2)
During transient cerebral ischemia, intracellular calcium increases initiating a cascade of events which leads to the delayed death of neurons located in the hippocampus. Coupled to this calcium disturbance is the rapid decrease of calcium/calmodulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cd75ab2671fa2bfef76cc4f3228d5c
https://pubmed.ncbi.nlm.nih.gov/8821762
https://pubmed.ncbi.nlm.nih.gov/8821762
Publikováno v:
Brain research. 636(1)
Centrally injected neuropeptide Y (NPY) is a potent stimulant of ingestive behavior capable of augmenting both food and fluid intake in fully satiated animals. To gain further insight into NPY's mechanism of action, we recorded patterns of licking be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416498d19441d5a534415026663d079c
https://pubmed.ncbi.nlm.nih.gov/8156407
https://pubmed.ncbi.nlm.nih.gov/8156407