Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Alex M Dickens"'
Autor:
Federico Torta, Nils Hoffmann, Bo Burla, Irina Alecu, Makoto Arita, Takeshi Bamba, Steffany A. L. Bennett, Justine Bertrand-Michel, Britta Brügger, Mónica P. Cala, Dolores Camacho-Muñoz, Antonio Checa, Michael Chen, Michaela Chocholoušková, Michelle Cinel, Emeline Chu-Van, Benoit Colsch, Cristina Coman, Lisa Connell, Bebiana C. Sousa, Alex M. Dickens, Maria Fedorova, Finnur Freyr Eiríksson, Hector Gallart-Ayala, Mohan Ghorasaini, Martin Giera, Xue Li Guan, Mark Haid, Thomas Hankemeier, Amy Harms, Marcus Höring, Michal Holčapek, Thorsten Hornemann, Chunxiu Hu, Andreas J. Hülsmeier, Kevin Huynh, Christina M. Jones, Julijana Ivanisevic, Yoshihiro Izumi, Harald C. Köfeler, Sin Man Lam, Mike Lange, Jong Cheol Lee, Gerhard Liebisch, Katrice Lippa, Andrea F. Lopez-Clavijo, Malena Manzi, Manuela R. Martinefski, Raviswamy G. H. Math, Satyajit Mayor, Peter J. Meikle, María Eugenia Monge, Myeong Hee Moon, Sneha Muralidharan, Anna Nicolaou, Thao Nguyen-Tran, Valerie B. O’Donnell, Matej Orešič, Arvind Ramanathan, Fabien Riols, Daisuke Saigusa, Tracey B. Schock, Heidi Schwartz-Zimmermann, Guanghou Shui, Madhulika Singh, Masatomo Takahashi, Margrét Thorsteinsdóttir, Noriyuki Tomiyasu, Anthony Tournadre, Hiroshi Tsugawa, Victoria J. Tyrrell, Grace van der Gugten, Michael O. Wakelam, Craig E. Wheelock, Denise Wolrab, Guowang Xu, Tianrun Xu, John A. Bowden, Kim Ekroos, Robert Ahrends, Markus R. Wenk
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract In this community effort, we compare measurements between 34 laboratories from 19 countries, utilizing mixtures of labelled authentic synthetic standards, to quantify by mass spectrometry four clinically used ceramide species in the NIST (Na
Externí odkaz:
https://doaj.org/article/e8653562ef70466097f27cb7fad363e8
Autor:
Ilias Thomas, Virginia F.J. Newcombe, Alex M. Dickens, Sophie Richter, Jussi P. Posti, Andrew I.R. Maas, Olli Tenovuo, Tuulia Hyötyläinen, András Büki, David K. Menon, Matej Orešič
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110654- (2024)
Summary: Acute traumatic brain injury (TBI) is associated with substantial abnormalities in lipid biology, including changes in the structural lipids that are present in the myelin in the brain. We investigated the relationship between traumatic micr
Externí odkaz:
https://doaj.org/article/9c693a5cf0a34da68aa4dfce2e9560df
Autor:
Mikael Laaksonen, Jaakko Rinne, Melissa Rahi, Jussi P. Posti, Ruut Laitio, Juri Kivelev, Ilkka Saarenpää, Dan Laukka, Juhana Frösen, Antti Ronkainen, Stepani Bendel, Jaakko Långsjö, Marika Ala-Peijari, Jani Saunavaara, Riitta Parkkola, Mikko Nyman, Ilkka K. Martikainen, Alex M. Dickens, Juha Rinne, Mika Valtonen, Teijo I. Saari, Timo Koivisto, Paula Bendel, Timo Roine, Antti Saraste, Tero Vahlberg, Juha Tanttari, Timo Laitio
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Aneurysmal subarachnoid hemorrhage (aSAH) is a neurological emergency, affecting a younger population than individuals experiencing an ischemic stroke; aSAH is associated with a high risk of mortality and permanent disability. The
Externí odkaz:
https://doaj.org/article/9d946299390741bfa6d617d14bb790b5
Autor:
Alex M. Dickens, Tory P. Johnson, Santosh Lamichhane, Anupama Kumar, Carlos A. Pardo, Erie G. Gutierrez, Norman Haughey, Mackenzie C. Cervenka
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: This study aims to test the hypothesis that increased ketone body production resulting from a ketogenic diet (KD) will correlate with reductions in pro-inflammatory cytokines and lipid subspecies and improved clinical outcomes in adults
Externí odkaz:
https://doaj.org/article/32b26ad926d34d81b35d2df2791b6aab
Autor:
Santosh Lamichhane, Partho Sen, Alex M. Dickens, Matilda Kråkström, Jorma Ilonen, Johanna Lempainen, Heikki Hyöty, Riitta Lahesmaa, Riitta Veijola, Jorma Toppari, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Aims/hypothesisAppearance of multiple islet cell autoantibodies in early life is indicative of future progression to overt type 1 diabetes, however, at varying rates. Here, we aimed to study whether distinct metabolic patterns could be identified in
Externí odkaz:
https://doaj.org/article/3580584f61c242bda4a93b24851cb332
Autor:
Ilias Thomas, Alex M. Dickens, Jussi P. Posti, Endre Czeiter, Daniel Duberg, Tim Sinioja, Matilda Kråkström, Isabel R. A. Retel Helmrich, Kevin K. W. Wang, Andrew I. R. Maas, Ewout W. Steyerberg, David K. Menon, Olli Tenovuo, Tuulia Hyötyläinen, András Büki, Matej Orešič, CENTER-TBI Participants and Investigators
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Traumatic brain injury is associated with changes to the metabolome. Here the authors show that acute traumatic brain injury has distinctive serum metabolic patterns which may suggest protective changes of systemic lipid metabolism aiming to maintain
Externí odkaz:
https://doaj.org/article/5647d4f3026c469abc78664e5c748a91
Autor:
Matilda Kråkström, Alex M. Dickens, Marina Amaral Alves, Sofia D. Forssten, Arthur C. Ouwehand, Tuulia Hyötyläinen, Matej Orešič, Santosh Lamichhane
Publikováno v:
Metabolites, Vol 13, Iss 3, p 355 (2023)
Current evidence suggests that gut microbiome-derived lipids play a crucial role in the regulation of host lipid metabolism. However, not much is known about the dynamics of gut microbial lipids within the distinct gut biogeographic. Here we applied
Externí odkaz:
https://doaj.org/article/b9072a4beacc4cd2bb0377f6183427e2
Autor:
Aidan McGlinchey, Tim Sinioja, Santosh Lamichhane, Partho Sen, Johanna Bodin, Heli Siljander, Alex M. Dickens, Dawei Geng, Cecilia Carlsson, Daniel Duberg, Jorma Ilonen, Suvi M. Virtanen, Hubert Dirven, Hanne Friis Berntsen, Karin Zimmer, Unni C. Nygaard, Matej Orešič, Mikael Knip, Tuulia Hyötyläinen
Publikováno v:
Environment International, Vol 143, Iss , Pp 105935- (2020)
In the last decade, increasing incidence of type 1 diabetes (T1D) stabilized in Finland, a phenomenon that coincides with tighter regulation of perfluoroalkyl substances (PFAS). Here, we quantified PFAS to examine their effects, during pregnancy, on
Externí odkaz:
https://doaj.org/article/a57c59559b8749bc97a4d90ab4a1fb89
Autor:
Alex M. Dickens, Seung Wan Yoo, Alfred C. Chin, Jiadi Xu, Tory P. Johnson, Amanda L. Trout, Kurt F. Hauser, Norman J. Haughey
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The widespread use of combinational antiretroviral therapies (cART) in developed countries has changed the course of Human Immunodeficiency Virus (HIV) infection from an almost universally fatal disease to a chronic infection for the majorit
Externí odkaz:
https://doaj.org/article/a9afe25e6dc247338322f014d0f67320
Autor:
Anna-Katariina Aatsinki, Santosh Lamichhane, Heidi Isokaanta, Partho Sen, Matilda Krakstrom, Marina Amaral Aves, Anniina Johanna Keskitalo, Eveliina Munukka, Hasse Karlsson, Laura E Perasto, Minna Lukkarinen, Matej Oresic, Henna-Maria Kailanto, Linnea Karlsson, Leo Lahti, Alex M Dickens
Early-life gut microbiome-metabolome crosstalk has a pivotal role in the maintenance of host physiology. However, our understanding on early-life gut microbiome-metabolome maturation trajectories in humans remains limited. This study aims to explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d4ace9c4ce0cf1314e01072b282c1a
https://doi.org/10.1101/2023.05.29.23290441
https://doi.org/10.1101/2023.05.29.23290441
