Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alex L, Nigg"'
Autor:
Roberto Stabile, Mario Román Cabezas, Mathijs P. Verhagen, Francesco A. Tucci, Thierry P. P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Alex L. Nigg, Meng Chen, Cristina Ivan, Masayoshi Shimizu, Senada Koljenović, Jose A. Hardillo, C. Peter Verrijzer, Robert J. Baatenburg de Jong, George A. Calin, Riccardo Fodde
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-13 (2023)
Abstract Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation and in the epigenetic control of embryonic stem ce
Externí odkaz:
https://doaj.org/article/f7824d98a84b4c1d9d47b1294a00ba7e
Autor:
Karin Legerstee, Tsion E. Abraham, Wiggert A. van Cappellen, Alex L. Nigg, Johan A. Slotman, Adriaan B. Houtsmuller
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of three layers. We used structured illumination mic
Externí odkaz:
https://doaj.org/article/04042c18fbe1426ea391cb28c528894f
Identifying Molecular Changes in Early Cervical Cancer Samples of Patients That Developed Metastasis
Autor:
Vera de Geus, Patricia C. Ewing-Graham, Willem de Koning, Maurits N. C. de Koning, Thierry P. P. van den Bosch, Alex L. Nigg, Casper H. J. van Eijck, Marta Jozwiak, Heleen J. van Beekhuizen, Dana A. M. Mustafa
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Cervical cancer is one of the most common cancers in women worldwide. Patients diagnosed with early-stage cervical cancer have a good prognosis, however, 10-20% suffer from local or distant recurrent disease after primary treatment. Treatment options
Externí odkaz:
https://doaj.org/article/83c09f01613e4e1dbc7b273099940269
Autor:
Simona V. Gornati, Carmen B. Schäfer, Oscar H.J. Eelkman Rooda, Alex L. Nigg, Chris I. De Zeeuw, Freek E. Hoebeek
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2690-2704 (2018)
The cerebellum plays a role in coordination of movements and non-motor functions. Cerebellar nuclei (CN) axons connect to various parts of the thalamo-cortical network, but detailed information on the characteristics of cerebello-thalamic connections
Externí odkaz:
https://doaj.org/article/7958ff97741b40bd9eafa8a7509b0b4a
Autor:
Marieke van der Zwan, MD, Carla C. Baan, PhD, Robert B. Colvin, MD, PhD, Rex N. Smith, MD, PhD, Rebecca A. White, Dorothy Ndishabandi, Alex L. Nigg, Thierry P.P. van den Bosch, PhD, Gretchen N. de Graav, MD, PhD, Marian C. Clahsen-van Groningen, MD, PhD, Dennis A. Hesselink, MD, PhD
Publikováno v:
Transplantation Direct, Vol 5, Iss 1, p e418 (2019)
Background. Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor–based therapy, however, with an increased risk of acute T cell-mediate
Externí odkaz:
https://doaj.org/article/932b155d9b794b31a623b1ecca59389a
Autor:
Sara Sepe, Chiara Milanese, Sylvia Gabriels, Kasper W.J. Derks, Cesar Payan-Gomez, Wilfred F.J. van IJcken, Yvonne M.A. Rijksen, Alex L. Nigg, Sandra Moreno, Silvia Cerri, Fabio Blandini, Jan H.J. Hoeijmakers, Pier G. Mastroberardino
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1866-1875 (2016)
The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accum
Externí odkaz:
https://doaj.org/article/7126e1c82c7a4a0aa0b46f30f13acd3f
Autor:
Johan A. Slotman, Tsion E Abraham, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Karin Legerstee, Alex L. Nigg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, 11(1):2315. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, 11(1):2315. Nature Publishing Group
Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of three layers. We used structured illumination microscopy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac43cdbfbb43afec40c1519698e6a86
https://doi.org/10.1038/s41598-021-81898-x
https://doi.org/10.1038/s41598-021-81898-x
Autor:
Freek E. Hoebeek, Oscar H J Eelkman Rooda, Alex L. Nigg, Simona V. Gornati, Chris I. De Zeeuw, Carmen B. Schäfer
Publikováno v:
Cell Reports [E], 23(9), 2690. Cell Press
Cell Reports, Vol 23, Iss 9, Pp 2690-2704 (2018)
Cell Reports, 23(9), 2690-2704. Cell Press
Cell Reports
Cell Reports, Vol 23, Iss 9, Pp 2690-2704 (2018)
Cell Reports, 23(9), 2690-2704. Cell Press
Cell Reports
Summary The cerebellum plays a role in coordination of movements and non-motor functions. Cerebellar nuclei (CN) axons connect to various parts of the thalamo-cortical network, but detailed information on the characteristics of cerebello-thalamic con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2d5fe9fb1c02e17dc6be615b1e7a6d
https://doi.org/10.1016/j.celrep.2018.04.098
https://doi.org/10.1016/j.celrep.2018.04.098
Autor:
Bettina E. Hansen, Guoying Zhou, Marco J. Bruno, Kostandinos Sideras, Boris Galjart, Cornelis Verhoef, Katharina Biermann, Stefan Sleijfer, Shanta Mancham, Dave Sprengers, H. Stoop, Angela Vasaturo, Jaap Kwekkeboom, Alexander Pedroza-Gonzalez, Alex L. Nigg
Publikováno v:
Journal of Surgical Oncology, 118(1), 68-76. Wiley-Liss Inc.
Background and objectives Patients with isolated colorectal-cancer-liver-metastases (CRCLM) frequently undergo metastatectomy. Tumor-infiltrating-lymphocytes (TILs) have prognostic potential in the setting of primary colorectal cancer, however, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624c9f01aab6027015772b7339b00f09
https://doi.org/10.1002/jso.25091
https://doi.org/10.1002/jso.25091
Autor:
Eric A.P. Steegers, Emilie M. Herzog, Paul H. C. Eilers, Anniek Reijnierse, Anton J.M. Roks, Martina A.M. Kerkhof, Ronald R. de Krijger, Alex J. Eggink, Irwin K.M. Reiss, Régine P.M. Steegers-Theunissen, Alex L. Nigg
Publikováno v:
Placenta, 49, 72-79. W.B. Saunders
Placenta, 49, 72. W.B. Saunders Ltd
Placenta, 49, 72. W.B. Saunders Ltd
Introduction Offspring exposed to preeclampsia (PE) show an increased risk of cardiovascular disease in adulthood. We hypothesize that this is mediated by a disturbed vascular development of the placenta, umbilical cord and fetus. Therefore, we inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0835681281f611b814c690c7268db15
https://hdl.handle.net/1765/108253
https://hdl.handle.net/1765/108253