Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alex L, Nguyen"'
Autor:
David A. Colby, James R. Woods, Cassidy S. Baldwin, Frank R. Fronczek, Hari Khatri, Alex L. Nguyen
Publikováno v:
J Org Chem
Although there are many synthetic methods to produce fluorinated and trifluoromethylated organic structures, the construction of difluoromethylated compounds remains a synthetic challenge. We have discovered that using magnesium salts and organic bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8b08b0b9e2b719128705738e6ead9f
https://doi.org/10.1021/acs.joc.7b03014
https://doi.org/10.1021/acs.joc.7b03014
Autor:
Kaitlin E. Griffin, Alex L. Nguyen, Kevin M. Smith, M. Graça H. Vicente, Frank R. Fronczek, Zehua Zhou
Publikováno v:
New Journal of Chemistry. 42:8241-8246
A series of BODIPYs bearing one (4b,c), two (6a) or three (3b) glucose units attached to the meso(8) and the boron atom positions were synthesized using a Cu(I)-catalyzed Huisgen cycloaddition reaction. The resulting 1,2,3-triazole-BODIPYs were chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3fe5e3629435d1dce2e0815d07a2a14
https://doi.org/10.1039/c8nj00041g
https://doi.org/10.1039/c8nj00041g
Autor:
Stewart W. Humble, Hui Chen, Alex L. Nguyen, M. Graça H. Vicente, Kevin M. Smith, Zehua Zhou, R. G. Waruna Jinadasa
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 21:354-363
Syntheses of three new chlorin e6 conjugates for PDT of tumors are reported. One of the new compounds 17 is conjugated with lysine at the 131-position, but the others are mono-conjugated 14 or diconjugated 15 with the non-amino acid species ethanolam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b99053b22314212162e7c3e48620761
https://doi.org/10.1142/s1088424617500262
https://doi.org/10.1142/s1088424617500262
Autor:
M. Graça H. Vicente, Maodie Wang, Frank R. Fronczek, Quynh Do, Petia Bobadova-Parvanova, Alex L. Nguyen, Zehua Zhou, Kevin M. Smith
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 20:1409-1419
A series of boron-functionalized BODIPY dyes with cyano groups were prepared from their corresponding BF2derivatives using SnCl4/TMSCN at room temperature for 10 min. Replacement of the fluorines by cyano groups reduces the B–N bond lengths, decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501043de81743664ac756095c1284108
https://doi.org/10.1142/s108842461650125x
https://doi.org/10.1142/s108842461650125x
Publikováno v:
Tetrahedron Letters. 56:6348-6351
A series of 14 symmetric ( 1a – g ) and asymmetric ( 2a – g ) BODIPYs bearing two different substituents at the boron center were synthesized in a one-pot reaction from dipyrrins 1 and 2 , respectively, in 14–63% isolated yields. The reaction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a8fbb0ffb68eeb6d28b9b839278b98
https://doi.org/10.1016/j.tetlet.2015.09.119
https://doi.org/10.1016/j.tetlet.2015.09.119
Autor:
Hui, Chen, Stewart W, Humble, R G, Waruna Jinadasa, Zehua, Zhou, Alex L, Nguyen, M Graça H, Vicente, Kevin M, Smith
Publikováno v:
Journal of porphyrins and phthalocyanines. 21(4-6)
Syntheses of three new chlorin e6 conjugates for PDT of tumors are reported. One of the new compounds 17 is conjugated with lysine at the 131-position, but the others are mono-conjugated 14 or diconjugated 15 with the non-amino acid species ethanolam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e7609663bfb939c3aa5476dec6f3c1a
https://pubmed.ncbi.nlm.nih.gov/29056848
https://pubmed.ncbi.nlm.nih.gov/29056848
Publikováno v:
Organic Letters. 14:3676-3679
Activation of primary aliphatic alcohols with triphosgene and triethylamine mixtures afforded either alkyl chloride or diethylcarbamate products, and the switch in selectivity appeared to be driven by sterics. The reaction conditions to achieve this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b01cc828bc67625763123820028911d
https://doi.org/10.1021/ol301520d
https://doi.org/10.1021/ol301520d
Autor:
Alex L. Nguyen, Frank R. Fronczek, Lijuan Jiao, Kevin M. Smith, Hui Chen, R. G. Waruna Jinadasa
Since the patent for the photodynamic therapy agent Talaporfin (mono-L-aspartylchlorin e6) was issued in 1987, confusion has existed regarding which of the three carboxylic acid groups in the chlorophyll degradation product, chlorin e6 (1), is modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b9c2d018585fc99bdc0569421e11a8
https://europepmc.org/articles/PMC4525479/
https://europepmc.org/articles/PMC4525479/
Autor:
Petia Bobadova-Parvanova, Kevin M. Smith, M. Graça H. Vicente, Alex L. Nguyen, Frank R. Fronczek, Melissa Hopfinger
Publikováno v:
Inorganic chemistry. 54(7)
A series of boron-disubstituted O-BODIPYs were synthesized, and their structures and spectroscopic properties were investigated using both computational and experimental methods. Three methods were investigated for the preparation of 4,4-dimethoxy-BO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbddf5c7bc0f6cf52a2bd5fc2477806
https://pubmed.ncbi.nlm.nih.gov/25797597
https://pubmed.ncbi.nlm.nih.gov/25797597
Publikováno v:
ChemInform. 43
Diols bearing a primary and a tertiary hydroxyl group such as (Ia) and (Ib) are selectively chlorinated at the primary function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48acf8a3162948964ff6054465b8bcf
https://doi.org/10.1002/chin.201246036
https://doi.org/10.1002/chin.201246036