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Autor:
Nien-Du Yang, Richard Kanyo, Lu Zhao, Jingru Li, Po Wei Kang, Alex Kelly Dou, Kelli McFarland White, Jingyi Shi, Jeanne M. Nerbonne, Harley T. Kurata, Jianmin Cui
Publikováno v:
Science Advances. 8
KCNQ2 and KCNQ3 form the M-channels that are important in regulating neuronal excitability. Inherited mutations that alter voltage-dependent gating of M-channels are associated with neonatal epilepsy. In the homolog KCNQ1 channel, two steps of voltag