Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alex Joun"'
Autor:
J. Milburn Jessup, Mohamed Kabbout, Nikolay Korokhov, Alex Joun, Ann E. Tollefson, William S. M. Wold, Abid R. Mattoo
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 3, Pp 636-644 (2020)
Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of tumor. We postulate that combining two ICD inducers may cause durable regression in immunocom
Externí odkaz:
https://doaj.org/article/7622a97b8b444b8e842a4c3dfe239e59
S1. Immuno-staining of Clone A for MCL-1 S2. Autophagy is not involved in enhanced killing of Clone A and SF-539 cell lines by combination treatments S3. Combination treatment of Everolimus or AZD2014 and Olaparib fails to increase PARP cleavage in C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826423386c666a4a60c6e066c7684302
https://doi.org/10.1158/1541-7786.22515315
https://doi.org/10.1158/1541-7786.22515315
MCL-1, a member of the antiapoptotic BCL-2 family, is a prosurvival protein with an essential DNA repair function. This study aims to test whether inhibition of protein synthesis by mTOR complex (mTORC) inhibitors depletes MCL-1, suppresses homologou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2239dc2ce5bf7fac93050271b284e979
https://doi.org/10.1158/1541-7786.c.6541038
https://doi.org/10.1158/1541-7786.c.6541038
Autor:
Nikolay Korokhov, Alex Joun, William S. M. Wold, Ann E. Tollefson, J. Milburn Jessup, Abid R. Mattoo, Mohamed Kabbout
Publikováno v:
Human Vaccines & Immunotherapeutics
Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of tumor. We postulate that combining two ICD inducers may cause durable regression in immunocom
Publikováno v:
Molecular cancer research : MCR. 17(1)
MCL-1, a member of the antiapoptotic BCL-2 family, is a prosurvival protein with an essential DNA repair function. This study aims to test whether inhibition of protein synthesis by mTOR complex (mTORC) inhibitors depletes MCL-1, suppresses homologou